Table 2.
Probability of changes in relative concentrations of metabolites that differed in culture medium between transferred embryos later diagnosed as pregnant or open at Day-40, Day-62 and birth, and between embryos that miscarried after Day-40 vs. embryos that never reached pregnancy and vs. embryos that reached pregnancy to term.
| Birth | Day-62 | Day-40 | Miscarriage | |||||
|---|---|---|---|---|---|---|---|---|
| Metabolite | p-Value | Bon | p-Value | Bon | p-Value | Bon | p-Value | Bon |
| l-Leucine | 0.0454 | 0.05 | ||||||
| l-Lysine | 0.0494 | 0.05 | 0.009 | 0.05 | 0.0143 | 0.05 | ||
| Palmitoylethanolamide | 0.0782 | 0.10 | ||||||
| l-Valine | 0.0439 | 0.05 | 0.0729 | 0.05 | ||||
| l-Glutamic acid | 0.0740 | 0.05 | 0.0844 | 0.05 | ||||
| Dimethyl adipate | 0.0774 | 0.05 | 0.0266 | 0.05 | 0.0018 | 0.05 | ||
| Lauroyl diethanolamide | 0.0112 | 0.05 | ||||||
| Phosphatidylethanolamine(18:2/20:2) | 0.0518 | 0.05 | 0.0168 | 0.05 | ||||
GLM analysis parametrized with the following factors: embryo cryopreservation, culture, bull breed, embryonic stages -0 h and 24 h-, and embryonic age. Significant p-values are stated as p < 0.05, and tendencies 0.05 > p < 0.10. Bonferroni (Bon) as a false discovery rate value at levels p < 0.05 and p < 0.10.