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. 2021 Aug 8;26(16):4803. doi: 10.3390/molecules26164803

Figure 2.

Figure 2

Inhibitory effect of TY-1 on SARS-CoV-2 infection of cells. (a,b): SARS-CoV-2 (ancestral strain)-added cells were incubated at 37 °C for 1 h in the presence of dextrin (25 μg/mL) or TY-1 (50 μg/mL); then, the cell culture media was removed. The cells were additionally incubated in 1.55% carboxymethyl cellulose sodium salt-containing virus growth medium (VGM) without dextrin or TY-1 at 37 °C for 3 d. (a) Plaques in representative wells, inoculated with 104-times diluted SARS-CoV-2 are shown. (b) The viral titer (× 105 PFU/mL) in each test group is shown. The detection limit of the viral titer was 0.00004 × 105 PFU/mL. The results are indicated as mean ± SD (n = 8 per group). Student’s t-tests were performed to evaluate the statistical significance of the differences between the dextrin and each of the TY-1 groups; ** p < 0.01.