Table 1.

Age and sex distribution of patient cohorts used in this study.

Patient cohorts	Cystic Fibrosis (CF)			Healthy controls (HC)		Rheumatoid arthritis (RA)	Systemic Lupus Erythematosus (SLE)
Patient cohorts	CF1	CF2	CF3	HC1	HC2	Rheumatoid arthritis (RA)	Systemic Lupus Erythematosus (SLE)
Collection site	Emory			UGA	Emory	UAB	UMI
Specimen	Sputum	Serum
n =	70	32	66	23	4	20	10
Gender
% female	44.3% (n=31)	43.8% (n=14)	33.8% (n=22)	30.4% (n=7)	100% (n=4)	60.0% n=12)	90.0% (n=9)
% male	54.2% (n=39)	56.2% (n=18)	66.2% (n=44)	69.6% (n=16)	0% (n=0)	40.0% (n=8)	10.0% (n=1)
Age (yrs, mean+/−S.D.) (age range, min.–max.)	31.0+/−9.1 (19 – 61)	31.5+/−9.3 (18 – 55)	20.6+/−14.1 (1 – 61)	29.2+/−11.6 (18 – 66)	17.5+/−0.6 (17 – 18)	32.5+/−4.8 (27 – 44)	37.7+/−8.5 (21 – 50)
Age (yrs, mean+/−S.D.) (age range, min.–max.)	Adults		Adults, children	Adults	Children	Adults
FEV₁%_pred	66.4+/−23.7% (20.4–117.5%)	78.2+/−20.8% (35.4–110.8%)	-	-	-	-	-

FEV₁%_pred: forced expiratory volume in one percent predicted; CF: cystic fibrosis; HC: healthy controls; RA: rheumatoid arthritis; SLE: systemic lupus erythematosus; UGA: University of Georgia; UAB: University of Alabama; UMI: University of Michigan; S.D.: standard deviation.