Comparative genomic analysis reveals multiple independent acquisitions of fab1 and rfab1 across B. fragilis strains. B. fragilis strains (numbered 1 to 92; Table S2) that carry a fab1 homolog are in red, and strains with no identified fab1 homolog are in black. (Bottom) Whole-genome phylogeny; (top) presence of fpn (purple, light blue, dark blue, orange, or yellow), fab1 (red), rfab1 (green), or bft (gray). Empty boxes indicate that no homolog was identified.