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. 2021 Jul 20;6(4):e00383-21. doi: 10.1128/mSystems.00383-21

TABLE 1.

Correlation analysis of transporter family with both genome size and CDS numbera

Genome content TC no. Family Correlation coefficient P value
Genome size 2.A.1 Major facilitator superfamily (MFS) 0.73 0
CDS no. 2.A.1 0.66 0
Genome size 2.A.1.3 Drug:H+ antiporter-2 (14-spanner) (DHA2) family 0.73 0
CDS no. 2.A.1.3 0.66 0
Genome size 2.A.1.76 Uncharacterized major facilitator 24 family 0.69 0
CDS no. 2.A.1.76 0.61 4.44E−16
Genome size 2.A.1.32 Putative aromatic compound/drug exporter (ACDE) family 0.68 0
CDS no. 2.A.1.32 0.60 8.88E−16
Genome size 2.A.1.6 Metabolite:H+ symporter (MHS) family 0.66 0
CDS no. 2.A.1.6 0.67 0
Genome size 2.A.3 Amino acid-polyamine-organocation (APC) superfamily 0.67 0
CDS no. 2.A.3 0.61 2.22E−16
Genome size 2.A.3.1 Amino acid transporter (AAT) family 0.71 0
CDS no. 2.A.3.1 0.66 0
Genome size 2.A.3.3 Cationic amino acid transporter (CAT) family 0.68 0
CDS no. 2.A.3.3 0.60 8.88E−16
Genome size 3.A.1 ATP-binding cassette (ABC) superfamily 0.75 0
CDS no. 3.A.1 0.69 0
Genome size 3.A.1.5 Peptide/opine/nickel uptake transporter (PepT) family 0.72 0
CDS no. 3.A.1.5 0.68 0
Genome size 3.A.1.3 Polar amino acid uptake transporter (PAAT) family 0.73 0
CDS no. 3.A.1.3 0.66 0
Genome size 3.A.1.155 Phage infection protein (PIP) family 0.72 0
CDS no. 3.A.1.155 0.63 0
Genome size 3.A.1.104 Teichoic acid exporter (TAE) family 0.68 0
CDS no. 3.A.1.104 0.60 1.33E−15
Genome size 1.A.112 Cyclin M Mg2+ exporter (CNNM) family 0.72 0
CDS no. 1.A.112 0.70 0
Genome size 1.A.8 Major intrinsic protein (MIP) family 0.70 0
CDS no. 1.A.8 0.61 2.22E−16
Genome size 1.A.35 CorA metal ion transporter (MIT) family 0.68 0
CDS no. 1.A.35 0.60 8.88E−16
Genome size 1.I.3 Bacterial (Planctomycetes) nuclear pore-like complex (B-NPC) family  0.63 0
CDS no. 1.I.3 0.62 2.22E−16
Genome size 2.A.23 Dicarboxylate/amino acid:cation (Na+ or H+) symporter (DAACS) family 0.71 0
CDS no. 2.A.23 0.65 0
Genome size 2.A.26 Branched-chain amino acid:cation symporter (LIVCS) family 0.61 4.44E−16
CDS no. 2.A.26 0.61 2.22E−16
Genome size 2.A.45 Arsenite-antimonite (ArsB) efflux family 0.60 1.11E−15
CDS no. 2.A.45 0.62 0
Genome size 2.A.118 Basic amino acid antiporter (ArcD) family 0.68 0
CDS no. 2.A.118 0.60 8.88E−16
Genome size 2.A.20 Inorganic phosphate transporter (PiT) family 0.68 0
CDS no. 2.A.20 0.60 8.88E−16
Genome size 2.A.108 Iron/lead transporter (ILT) family 0.69 0
CDS no. 2.A.108 0.61 4.44E−16
Genome size 2.A.76 Resistance to homoserine/threonine (RhtB) family 0.61 8.88E−16
CDS no. 2.A.76 0.61 4.44E−16
Genome size 3.A.6 Type III (virulence-related) secretory pathway (IIISP) family 0.62 0
CDS no. 3.A.6 0.62 0
Genome size 5.B.1 gp91phox phagocyte NADPH oxidase-associated cytochrome b558 (Phox) family 0.73 0
CDS no. 5.B.1 0.67 0
Genome size 9.B.34 Kinase/phosphatase/cyclic GMP synthase/cyclic di-GMP hydrolase (KPSH) family 0.75 0
CDS no. 9.B.34 0.76 0
Genome size 9.B.72 4 TMS GlpM (GlpM) family 0.63 0
CDS no. 9.B.72 0.63 0
a

TC, transporter classification. Boldface indicates superfamily.