Abstract
Three field strains of Mycoplasma suipneumoniae each inoculated into 3 gnotobiotic piglets produced macro- and microscopic lung lesions typical of enzootic pneumonia in 8 of the animals. Under similar conditions 3 strains of M. flocculare produced typical macroscopic lung lesions in just 1 out of 9 animals. It is therefore concluded that M. flocculare is not of primary etiologic importance in the porcine enzootic pneumonia complex.
The frequency of successful reisolation from nasal cavities, lungs, and other tissues indicated that the lungs are the sole natural habitat for M. suipneumoniae, while for M. flocculare lungs as well as nasal cavities should be regarded as the natural habitat.
None of the organisms apparently spread via the blood stream. M. flocculare, but not M. suipneumoniae, induced histologic alterations of the nasal mucosa.
Keywords: Mycoplasma sui pneumoniae, Mycoplasma flocculare, gnotobiotic piglets, porcine enzootic pneumonia, porcine rhinitis
Sammendrag
Tre nyisolerede stammer af Mykoplasma suipneumoniae hver podet på 3 gnotobiotiske grise fremkaldte i 8 af dyrene sådanne makroog mikroskopiske lungeforandringer, som er typiske for enzootisk pneumoni. I tilsvarende forsøg resulterede podning med 3 stammer af M. flocculare kun i opståen af lette, typiske makroskopiske lungeforandringer nos een af 9 grise. Derfor konkluderes, at M. flocculare er ikke af primser etiologisk betydning ved svinets enzootiske pneumoni.
Hyppigheden, med hvilken reisolationsforsøg lykkedes fra næsehuler, lunger samt andre lokaliteter, antydede, at lungerne er det eneste naturlige habitat for M. suipneumoniae; i modsætning til M. flocculare, for hvilken både lunger og næsehule må anses for at være det naturlige habitat.
Ingen af de 2 mykoplasma-arter syntes at spredes via blodbanerne. M. flocculare var i modsætning til M. suipneumoniae i stand til at fremkalde mikroskopiske forandringer i næsehulens slimhinde.
Full Text
The Full Text of this article is available as a PDF (1.4 MB).
References
- Friis N. F. Mycoplasmas cultivated from the respiratory tract of Danish pigs. Acta vet. scand. 1971;12:69–79. [PubMed] [Google Scholar]
- Friis N. F. Mycoplasma hyorhinis as a causative agent in pneumonia of pigs. Acta vet. scand. 1971;12:116–119. [PubMed] [Google Scholar]
- Friis N. F. Sensitivity of Mycoplasma suipneumoniae to penicillin-G. Acta vet. scand. 1971;12:120–121. [PubMed] [Google Scholar]
- Friis N. F. Isolation and characterization of a new porcine mycoplasma. Acta vet. scand. 1972;13:284–286. doi: 10.1186/BF03548588. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Friis N. F. The pathogenicity of Mycoplasma flocculare. Acta vet. scand. 1973;14:344–346. doi: 10.1186/BF03547455. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Goodwin R. F. W. Isolation of Mycoplasma suipneumoniae from the nasal cavities and lungs of pigs affected with enzootic pneumonia or exposed to this infection. Res. vet. Sci. 1972;13:262–267. doi: 10.1016/S0034-5288(18)34038-4. [DOI] [PubMed] [Google Scholar]
- Goodwin R. F. W., Pomeroy A. P., Whittlestone P. Production of enzootic pneumonia in pigs with a mycoplasma. Vet. Rec. 1965;77:1247–1249. doi: 10.1136/vr.77.37.1070. [DOI] [Google Scholar]
- Goodwin R. F. W., Pomeroy Annette P., Whittlestone P. Characterization of Mycoplasma suipneumoniae: a mycoplasma causing enzootic pneumonia of pigs. J. Hyg. (Lond.) 1967;65:85–96. doi: 10.1017/S0022172400045563. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Hodges R. T., Betts A. O., Jennings A. R. Production of pneumonia in gnotobiotic pigs with pure cultures of Mycoplasma hyopneumoniae. Vet. Rec. 1969;84:268–273. doi: 10.1136/vr.84.11.268. [DOI] [PubMed] [Google Scholar]
- Huhn R. G. Swine enzootic pneumonia: Age susceptibility and treatment schemata. Canad. J. comp. Med. 1971;35:77–81. [PMC free article] [PubMed] [Google Scholar]
- L’Ecuyer C. Enzootic pneumonia in pigs: Propagation of a causative mycoplasma in cell cultures and in artificial medium. Canad. J. comp. Med. 1969;33:10–19. [PMC free article] [PubMed] [Google Scholar]
- Maré C. J., Switzer W. P. New species : Mycoplasma hyopneumoniae. A causative agent of virus pig pneumonia. Vet. Med. 1965;60:841–846. [PubMed] [Google Scholar]
- Meyling A., Friis N. F. Serological identification of a new porcine mycoplasma species, M. flocculare. Acta vet. scand. 1972;13:287–289. doi: 10.1186/BF03548589. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Tauraso N. M. Effect of Diethylaminoethyl Dextran on the growth of mycoplasma in agar. J. Bact. 1967;93:1559–1564. doi: 10.1128/JB.93.5.1559-1564.1967. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Whittlestone, P.: The role of mycoplasmas in the production of pneumonia in the pig. In Pathogenic Mycoplasmas; A Ciba Foundation Symposium, pp. 263–283. Associated Scientific Publishers, Amsterdam 1972.