Figure 4.

Blood brain barrier integrity poststroke. Representative staining immunopositive to Fibrinogen in the peri-infact area of Wt,WT^bmt, Wt,SCD^bmt, IL1R^-/-,SCD^bmt and IL6^-/-,SCD^bmt mouse brains, and quantification (mean ± standard deviation). A Nikon SE upright microscope and a Nikon DS-Fi3 camera was used to capture 10x and 20x images of ipsilateral brain and 10x images of contralateral brain. Dotted line denotes transition between infarcted area and heathy tissue. *P<0.05, **P<0.01, ***P<0.005 as determined by ANOVA.