In this article, Figures 2A, 2B, 3B and 4B are not accurate, they are replaced with the attached Figures 2, 3 and 4, respectively. The authors express regrets for this mistake.
Figure 2.
Decrease in CD133+ CSCs population by UAC in vitro. A. Western blotting for CD133 in PLC/PRF/5 cells on treatment with different doses of UAC. B. UAC induces decrease in CD133 protein in a time-dependent manner. C. Effect of different concentrations of UAC on PLC/PRF/5 cell prolifera-tion (BrdUrd ELISA assay). D. Reduction in percent-age of CD133+ cells after UAC treatment (Flow cytometric analysis). *P<0.05.
Figure 3.
Induction of differentiation in HCC CSCs by UAC. A. The stem-ness-related gene expression of in CD133+ and CD133- cells, cultured as spheres in CDM or in a monolayer with UAC treatment. B. Western blotting shows that UAC enhances CK8/18 expression and decreases CK19 expression in a time dependent manner. *P<0.05.
Figure 4.
Inhibition of self-renewal and tumorigenic capacities of CD133+ CSCs by UAC. A. CD133+ and CD133- PLC/PRF/5 cells were pretreated with UAC for 10 days. Each group of cells was suspended in growth media containing 0.3% soft agar and seeded in 24-well plates to evaluate colony formation efficiency (CFE; n=3). B. Inhibition of capacity for CD133+ PLC/PRF/5 cell sphere formation by UAC. *P<0.05.