Figure 7.

Study of kainate-induced epilepsy. Eleven-month-old mice were subjected to three kainate injections (8 mg/kg every 30 min), and epileptic responses were analysed for 180 min after the first injection. (A) Percentage of mice reaching seizure Stages I to VI and kainate-induced mortality. (B) Percentage of time spent in each stage during the course of the experiment. Data are expressed as average ± SEM. n = 6 mice/group. Two-way ANOVA P-values display post hoc Bonferroni differences. (C) Number of seizures experienced per animal divided by time segments after the first, second and third kainate injections. Data are expressed as average ± SEM. n = 6 animals per group. Two-way ANOVA P-values display post hoc Bonferroni differences.