In response to the commentary article about our recent publication in Cell Biology International (https://doi.org/10.1002/cbin.11516), which states that Hemagglutinin‐esterase protein is absent in SARS‐Cov2 as reported in Table 2 of our publication, we acknowledge the error and seek for correction. This is largely due to the uncertainties and discoveries about the SARS‐COV‐2 virus. However, the information provided in our publication was validated by Ravi et al. (2020) but upon critical consideration and extensive reviews of the viral structural proteins, the Hemagglutinin‐esterase protein is absent in the SARS‐COV‐2 viral structure (Astuti & Ysrafil, 2020; Yin, 2020). Therefore, the following correction should be made accordingly:
Table 2.
A summary of SARS‐CoV‐2 structural proteins, binding sites, and their roles (Astuti & Ysrafil, 2020)
| Protein Name | Binding mechanism | Role |
|---|---|---|
| Spike protein (S) | Utilizes an N‐terminal signal sequence to gain access to the ER (endoplasmic reticulum) | Mediates attachment to host receptors |
| Nucleocapsid protein (N) | Binds the viral genome in a beads‐on‐a‐string type conformation | Tethers the viral genome to replicase‐transcriptase complex, packages the encapsulated genome into viral particles |
| Envelope protein (E) | A transmembrane protein with ion channel activity | Facilitates assembly and release of the virus; involved in ion channel activity |
| Membrane protein (M) | Binds to nucleocapsid | Promotes membrane curvature |
Tantuoyir, M. M. , & Rezaei, N. (2021). Serological tests for COVID‐19: Potential opportunities. Cell Biol Int, 45, 2199–2200. 10.1002/cbin.11686
The article that is the subject of this Commentary is available here: https://doi.org/10.1002/cbin.11516
DATA AVAILABILITY STATEMENT
Data sharing does not apply to this article as no new data were created or analyzed in this study.
REFERENCES
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Data Availability Statement
Data sharing does not apply to this article as no new data were created or analyzed in this study.