Skip to main content
Scientific Reports logoLink to Scientific Reports
. 2021 Sep 9;11:18377. doi: 10.1038/s41598-021-97918-9

Author Correction: Comparative profiling of cortical gene expression in Alzheimer’s disease patients and mouse models demonstrates a link between amyloidosis and neuroinflammation

Erika Castillo 1, Julio Leon 1,8, Guianfranco Mazzei 1, Nona Abolhassani 1, Naoki Haruyama 1, Takashi Saito 2, Takaomi Saido 2, Masaaki Hokama 1,9,✉, Toru Iwaki 3, Tomoyuki Ohara 4, Toshiharu Ninomiya 5, Yutaka Kiyohara 6, Kunihiko Sakumi 1, Frank M LaFerla 7, Yusaku Nakabeppu 1,✉
PMCID: PMC8429626  PMID: 34504282

Correction to: Scientific Reports 10.1038/s41598-017-17999-3, published online 19 December 2017

This article contains errors in the Introduction, where

“AppNL-G-F/NL-G-F mice carrying the homozygous mutant App gene encoding the humanised Aβ sequence (G601R, F606Y, and R609H) with three pathogenic mutations, namely Swedish (KM595/596NL), Beyreuther/Iberian (I641F), and Arctic (E618G)10, progressively exhibit Aβ accumulation starting at 4 to 6 months of age, dense distributions of microglia and astrocytes from 9 months of age, and behavioural symptoms from 8 to 12 months of age10,11.”

should read:

“AppNL-G-F/NL-G-F mice carrying the homozygous mutant App gene encoding the humanised Aβ sequence (G676R, F681Y, and R684H) with three pathogenic mutations, namely Swedish (KM670/671NL), Beyreuther/Iberian (I716F), and Arctic (E693G)10, progressively exhibit Aβ accumulation starting at 4 to 6 months of age, dense distributions of microglia and astrocytes from 9 months of age, and behavioural symptoms from 8 to 12 months of age10,11.”

In addition, in the Methods section, under the subheading ‘Animals’,

“Heterozygous App+/NL-G-F mice carrying humanised Aβ sequence (G601R, F606Y, R609H), Swedish (ML595/596NL), Beyreuther/Iberian (I641F), and Arctic (E618G) mutations, were previously established10.”

should read:

“Heterozygous App+/NL-G-F mice carrying humanised Aβ sequence (G676R, F681Y, R684H), Swedish (KM670/671NL), Beyreuther/Iberian (I716F), and Arctic (E693G) mutations, were previously established10.”


Articles from Scientific Reports are provided here courtesy of Nature Publishing Group

RESOURCES