Table 2.
Compound | % Activity | ||
---|---|---|---|
VEGFR-2 | CDK-1/cyclin B | HER-2 | |
15a | 96 | 91 | 95 |
15b | 100 | 100 | 93 |
15c | 100 | 91 | 99 |
15d | 91 | 85 | 90 |
15e | 98 | 88 | 86 |
15f | 96 | 91 | 100 |
15g | 100 | 92 | 83 |
15h | 100 | 95 | 97 |
15i | 85 | 89 | 87 |
15j | 90 | 91 | 93 |
15k | 90 | 92 | 92 |
15l | 92 | 51 | 52 |