Table 3.
Response Rates: Change in Terminal Hairs from Baseline. This table shows the post hoc stratified response by treatment group with a substantial increase in response in hair growth in the ALRV5XR group over time, while the placebo group's hair loss continues to progress. The ALRV5XR group separates into a trimodal responder pattern of low, moderate, and high responders when measured by absolute changes in Terminal Hair density however, these response rates are more uniform when stratified by per cent changes in Terminal Hair density. 54·5% of the ALRV5XR group increased their TH density by 10 or more THs/cm2 by week 24 and 18·2% of the group increased density by more than 25 THs/cm2.
| Placebo |
ALRV5XR |
|||
|---|---|---|---|---|
| Week 12 | Week 24 | Week 12 | Week 24 | |
| Positive responders | 50·0% | 18·2% | 91·9% | 100% |
| Terminal hairs/cm2 | ||||
| <0 | 50·0% | 81·8% | 9·1% | – |
| 0–5 | 40·0% | 18·2% | 27·3% | 45·5% |
| 5–10 | 10·0% | – | 27·3% | – |
| 10–15 | – | – | 18·2% | 27·3% |
| 15–20 | – | – | 9·1% | 9·1% |
| 20–25 | – | – | – | – |
| >25 | – | – | 9·1% | 18·2% |
| Max regrowth | 9 | 3 | 25 | 51 |
| Min regrowth | −17 | −12 | −3 | 0 |
| Terminal hairs (%) | ||||
| <0% | 50·0% | 81·8% | 9·1% | 0·0% |
| 0–5% | 40·0% | 18·2% | 45·5% | 45·5% |
| 5–10% | 10·0% | – | 27·3% | 9·1% |
| 10–15% | – | – | – | 18·2% |
| 15–20% | – | – | – | 9·1% |
| 20–25% | – | – | 18·2% | 9·1% |
| > 25% | – | – | – | 9·1% |
| Max regrowth | 7·0% | 1·6% | 22·9% | 46·8% |
| Min regrowth | −12·1% | −12·3% | 3·4% | 0% |