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. 2021 Feb 17;27(4):410–411. doi: 10.1016/j.molmed.2021.01.004

Epstein–Barr Virus in Multiple Sclerosis: Theory and Emerging Immunotherapies

(Trends in Molecular Medicine, 26:3 p:296-310, 2020)

Amit Bar-Or, Michael P Pender, Rajiv Khanna, Lawrence Steinman, Hans-Peter Hartung, Tap Maniar, Ed Croze , Blake T Aftab, Gavin Giovannoni, Manher A Joshi
PMCID: PMC8445335  PMID: 33608230

In our above review there is an error at the bottom of Figure 1 on the left: the text insert “Co-stimulatory survival signals (CD28-B7) inhibit T cell apoptosis allowing interaction with antigen-presenting cells (astrocytes/microglia)” should be replaced with “Co-stimulatory survival signals (B7) produced by EBV-infected B cells inhibit T cell apoptosis, allowing survival of autoreactive T cells”.

Original Figure 1

Unlabelled Image

The text insert “Co-stimulatory survival signals (CD28-B7) inhibit T cell apoptosis allowing interaction with antigen-presenting cells (astrocytes/microglia)” should be replaced with “Co-stimulatory survival signals (B7) produced by EBV-infected B cells inhibit T cell apoptosis, allowing survival of autoreactive T cells”


Articles from Trends in Molecular Medicine are provided here courtesy of Elsevier

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