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. 2021 Sep 1;7(9):e07895. doi: 10.1016/j.heliyon.2021.e07895

Figure 3.

Figure 3

α5IA increases CA1 place cell activity in adult F344s. A. Environment-dependent remapping of place fields recorded across successive sessions. Administration of α5IA (1.0 mg/kg, p.o.): B. increases MFR of CA1 place cells in a familiar environment; C. increases PFR in a familiar environment, D. increases In-field MFR in a familiar environment, E. has no effect on SIC in familiar or novel environments, F. has no effect on PFA in familiar or novel environments, and G. no significant effects treatment on place field spatial correlations upon exposure to environmental novelty. Significance: ∗p < 0.05. Data from 3 young adult F344 male rats.