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Frontiers in Neural Circuits logoLink to Frontiers in Neural Circuits
. 2021 Sep 6;15:727442. doi: 10.3389/fncir.2021.727442

Corrigendum: Inhibitory Network Bistability Explains Increased Interneuronal Activity Prior to Seizure Onset

Scott Rich 1,*, Homeira Moradi Chameh 1, Marjan Rafiee 1, Katie Ferguson 1,, Frances K Skinner 1,2,, Taufik A Valiante 1,3,4,5,6,
PMCID: PMC8450574  PMID: 34552473

In the original article, there was a mistake in Table 1 as published. The values of d and klow were swapped between the Control and 4-AP settings in this table, but correct in the associated code. The corrected Table 1 appears below.

Table 1.

Parameters used in neuron models.

Parameter Value (Control) Value (4-AP) Rationale
Cm 73 pF 49 pF Unpublished in-house experiment
vr −60.6 mV −60.6 mV Ferguson et al. (2013)
vt −43.1 mV −43.1 mV Ferguson et al. (2013)
vpeak 2.5 mV 2.5 mV Ferguson et al. (2013)
a 0.01 ms−1 0.01 ms−1 Parameter influences rheobase and adaptation exhibited by model*
b −0.2 nS −0.4 nS Parameter influences rheobase and adaptation exhibited by model*
c −67 mV −67 mV Ferguson et al. (2013)
d 0.75 pA 1.25 pA Parameter influences rheobase and adaptation exhibited by model*
klow 0.6 nS/mV 0.4 nS/mV Parameter influences rheobase and adaptation exhibited by model*
khigh 2 nS/mV 2 nS/mV Parameter influences rheobase and adaptation exhibited by model*
*

Differences in rheobase and adaptation in control and 4-AP neurons are features shown by Williams and Hablitz (2015) as well as observed in our un-published in-house experiment.

The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.

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References

  1. Ferguson K. A., Huh C. Y., Amilhon B., Williams S., Skinner F. K. (2013). Experimentally constrained ca1 fast-firing parvalbumin-positive interneuron network models exhibit sharp transitions into coherent high frequency rhythms. Front. Comput. Neurosci. 7:144. 10.3389/fncom.2013.00144 [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Williams S. B., Hablitz J. J. (2015). Differential modulation of repetitive firing and synchronous network activity in neocortical interneurons by inhibition of A-type K+ channels and Ih. Front. Cell. Neurosci. 9:89. 10.3389/fncel.2015.00089 [DOI] [PMC free article] [PubMed] [Google Scholar]

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