In the original article, there was a mistake in Table 1 as published. The values of d and klow were swapped between the Control and 4-AP settings in this table, but correct in the associated code. The corrected Table 1 appears below.
Table 1.
Parameters used in neuron models.
Parameter | Value (Control) | Value (4-AP) | Rationale |
---|---|---|---|
Cm | 73 pF | 49 pF | Unpublished in-house experiment |
vr | −60.6 mV | −60.6 mV | Ferguson et al. (2013) |
vt | −43.1 mV | −43.1 mV | Ferguson et al. (2013) |
vpeak | 2.5 mV | 2.5 mV | Ferguson et al. (2013) |
a | 0.01 ms−1 | 0.01 ms−1 | Parameter influences rheobase and adaptation exhibited by model* |
b | −0.2 nS | −0.4 nS | Parameter influences rheobase and adaptation exhibited by model* |
c | −67 mV | −67 mV | Ferguson et al. (2013) |
d | 0.75 pA | 1.25 pA | Parameter influences rheobase and adaptation exhibited by model* |
klow | 0.6 nS/mV | 0.4 nS/mV | Parameter influences rheobase and adaptation exhibited by model* |
khigh | 2 nS/mV | 2 nS/mV | Parameter influences rheobase and adaptation exhibited by model* |
Differences in rheobase and adaptation in control and 4-AP neurons are features shown by Williams and Hablitz (2015) as well as observed in our un-published in-house experiment.
The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated.
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References
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