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Journal of Extracellular Vesicles logoLink to Journal of Extracellular Vesicles
. 2021 Sep 20;10(11):e12149. doi: 10.1002/jev2.12149

Erratum: Exogenous loading of miRNAs into small extracellular vesicles

PMCID: PMC8452511  PMID: 34545682

de Abreu, R. C., Ramos, C. V., Becher, C., Lino, M., Jesus, C., da CostaMartins, P.A., Martins, P. A. T., Moreno, M. J., Fernandes, H., & Ferreira, L. (2021). Exogenous loading of miRNAs into small extracellular vesicles. Journal of Extracellular Vesicle, 10(10), e12111. https://doi.org/10.1002/jev2.12111

Reference citations are inadvertently placed in the caption of Figure 1, whereas there should not be any reference citation.

The correct caption for Figure 1 is:

Figure 1 Schematic representation of the different methods used to modulate sEVs with a Cy3‐labelled miRNA mimic and the follow‐up assays performed to validate the modulation and assess the bioactivity of the modulated sEVs. Five different methodologies have been used to load miRNAs into sEVs: transfection by Exo‐Fect or cholesterol‐modified miRNA and membrane permeabilization by a detergent (saponin), electroporation or heat shock (1). The modified sEVs were then characterized regarding their loading efficiency by fluorescence and qRT‐PCR analyses (2), bioactivity in the HEK‐293T reporter cell line (3), cell toxicity using a cell viability assay (4) and capacity to transfect cells (5).


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