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. 2021 Sep 1;162(11):bqab181. doi: 10.1210/endocr/bqab181

Table 8.

Potential bivalent genes critical for islet maturation

Gene Gene name Bivalency logFC FDR
2-week 10-week
Reg3g Regenerating islet-derived protein 3 gamma Y N 5.88 1.19E-07
Ccl5 C-C motif chemokine ligand 5 Y N 3.33 4.04E-07
Chst5 Carbohydrate sulfotransferase 5 Y N 2.75 4.19E-07
Fgf21 Fibroblast growth factor 21 Y N 2.98 1.65E-05
Tp63 Tumor protein p63 Y N 4.56 1.39E-04
Slco4c1 Solute carrier organic anion transporter family, member 4C1 Y N 2.64 2.52E-04
Zbp1 Z-DNA binding protein 1 Y N 3.49 3.75E-04
Sh2d4b SH2 domain containing 4B Y N 2.15 2.15E-03
Gzma Granzyme A Y N 2.56 1.08E-02
Cxcr2 C-X-C motif chemokine receptor 2 Y N 2.22 1.77E-02
Bpifa2f BPI fold containing family A, member 2F Y N 2.16 2.09E-02
Kmo Kynurenine 3-monooxygenase Y N 2.48 2.50E-02
Ankrd34a Ankyrin repeat domain 34A Y N 1.15 2.64E-02
Tnn Tenascin N Y N 3.00 3.95E-02
Serpina11 Serpin family A member 11 Y N 1.54 4.10E-02
Mxd3 Max dimerization protein 3 N Y -2.16 2.40E-07
Gdpd2 Glycerophosphodiester phosphodiesterase domain containing 2 N Y -3.11 2.01E-05
Camp Cathelicidin antimicrobial peptide N Y -5.50 2.71E-05
Rtkn2 Rhotekin 2 N Y -1.83 5.26E-05
Fam71f1 Family with sequence similarity 71, member F1 N Y -2.78 6.44E-05
Slc26a3 Solute carrier family 26 member 3 N Y -2.78 7.31E-04
Ebf4 EBF family member 4 N Y -1.68 8.02E-04
LOC303566 Homologous recombination factor with OB-fold N Y -1.54 1.43E-03
Dmgdh Dimethylglycine dehydrogenase N Y -3.37 1.61E-03
Tssk4 Testis-specific serine kinase 4 N Y -1.81 2.43E-03
Fabp7 Fatty acid binding protein 7 N Y -2.90 2.71E-03
Bglap Bone gamma-carboxyglutamate protein N Y -2.77 4.62E-03
Vnn3 Vanin 3 N Y -1.96 6.28E-03
Chad Chondroadherin N Y -1.59 6.29E-03
Sfta2 Surfactant associated 2 N Y -2.45 8.01E-03
Folh1 Folate hydrolase 1 N Y -1.87 9.84E-03
Hoxd10 Homeo box D10 N Y -2.22 1.41E-02
Cdh16 Cadherin 16 N Y -1.45 2.38E-02
Tsga10ip Testis-specific 10 interacting protein N Y -1.33 4.57E-02

Abbreviations: FDR, false discovery rate; N, no; Y, yes.