Correction: Targeting focal adhesion kinase overcomes erlotinib resistance in smoke induced lung cancer by altering phosphorylation of epidermal growth factor receptor

Original article: Oncoscience. 2018; 5:21–38. . https://doi.org/10.18632/oncoscience.395

This article has been corrected: Due to errors during figure assembly, the image for panel 3, column 1 in Figure 4B is an accidental duplicate of the image in panel 3, column 1 of Figure 4A. The corrected Figure 4 is shown below. The authors declare that these corrections do not change the results or conclusions of this paper.

Figure 4. Inhibition of FAK decreases the invasive property of lung cancer cells.

Invasion assays were carried out in a transwell system using Matrigel-coated filters and the number of cells that migrated to the lower chamber was counted. Cells that migrated are visualized following methylene blue staining in H358-S and NSCLC cell lines, H1299 and H1650 as indicated. (A) Cells were treated with either DMSO (vehicle control) or PF-562271 and invaded cells were photographed. Representative images were photographed at a magnification 10x. Invaded cells were counted and relative changes in invasive ability of H358-S and NSCLC cells upon inhibition with PF-562271 was calculated and represented graphically (^*p < 0.05). (B) Cells were transfected with either scrambled siRNA or FAK siRNA and invaded cells were photographed. Invaded cells were counted and relative changes in invasive ability of H358-S and NSCLC cells upon FAK silencing was calculated and represented graphically (^*p < 0.05). Representative images were photographed at a magnification 10x.

Original article: Oncoscience. 2018 Feb 23;5(1-2):21–38

PMCID: PMC5854290 PMID: 29556515

DOI: 10.18632/oncoscience.395