Table 1. A tabulated summary of the Cochrane risk of bias tool.

Cochrane criteria (Yes, No, Uncertain)	Cefalo et al. 2018 [20]	Lerchbaum et al. 2019 [19]	Safapour et al. 2020 [21]	Raed et al. 2017 [15]	McMullan et al. 2017 [16]	Karefykalis et al. 2018 [26]	Angellotti et al. 2019 [24]
Adequate sequence generation?	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Allocation concealment used?	Uncertain	Uncertain	Uncertain	Uncertain	Uncertain	Uncertain	Uncertain
Blinding?	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Are concurrent therapies similar?	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Incomplete outcome data addressed?	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Uniform and explicit outcome definitions?	Yes	Yes	Uncertain	Yes	Yes	Uncertain	Yes
Free of selective outcome reporting?	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Free of other bias?	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Overall risk of bias?	Yes	Yes	Yes	Yes	Yes	Yes	Yes
Our Evaluation	8/9 (High quality)	8/9 (High quality)	7/9 Medium quality)	8/9 (High quality)	8/9 (High quality)	7/9 (Medium quality)	8/9 (High quality)