Skip to main content
PLOS ONE logoLink to PLOS ONE
. 2021 Sep 24;16(9):e0257897. doi: 10.1371/journal.pone.0257897

Community risk perception and barriers for the practice of COVID-19 prevention measures in Northwest Ethiopia: A qualitative study

Aragaw Tesfaw 1,*, Getachew Arage 2, Fentaw Teshome 1, Wubet Taklual 1, Tigist Seid 3, Emaway Belay 1, Gashaw Mehiret 4
Editor: Johnson Chun-Sing Cheung5
PMCID: PMC8462701  PMID: 34559858

Abstract

Background

According to the World Health Organization, viral diseases continue to emerge and represent a serious issue for public health. The elderly and those with underlying chronic diseases are more likely to become severe cases. Our study sets out to present in-depth exploration and analyses of the community’s risk perception and barriers to the practice of COVID-19 prevention measures in South Gondar Zone, Northwest Ethiopia.

Methods

A qualitative study was done in three districts of South Gondar Zone. Community key informants and health extension workers were selected purposely for in-depth interviews and focus group discussion. The interviews were conducted by maintaining WHO recommendations for social distancing and use of appropriate personal protective equipment. The sample size for the study depended on the theoretical saturation of the data at the time of data collection. The qualitative data generated from in-depth interviews and focus group discussions was transcribed verbatim and translated into English language and thematically analyzed using open code software version 4.02.

Results

Three main themes and five categories emerged from the narrations of the participants regarding the perceived barriers for the practice of COVID-19 prevention measures. A total of 9 community key informants (5 women development armies (HDA), 2 health extension workers (HEW), and 2 religious leaders participated in the in-depth interview, while two focus group discussions (7 participants in each round) were conducted among purposely selected community members. The age of the participants ranged from 24 to 70 years with the median age of 48 years. The major identified barriers for practicing COVID-19 prevention measures were the presence of strong cultural and religious practices, perceiving that the disease does not affect the young, misinformation about the disease, and lack of trust in the prevention measures.

Conclusions

Socio-cultural, religious, and economic related barriers were identified from the participant’s narratives for the practice of COVID-19 prevention measures in south Gondar Zone. Our findings suggest the need to strengthen community awareness and education programs about the prevention measures of COVID-19 and increase diagnostic facilities with strong community-based surveillance to control the transmission of the pandemic.

Background

The world is closely watching the outbreak of respiratory illness associated with the novel beta coronavirus SARS-CoV-2 [1]. Initially termed 2019-nCoV, sequencing showed that the now officially named SARS-CoV-2 is 80–89% similar to bat severe acute respiratory syndrome-related coronaviruses found in Chinese horseshoe bats [2]. Prior to the global outbreak of SARS-CoV in 2003, HCoV-229E and HCoV-OC43 were the only coronaviruses known to infect humans. Following the SARS outbreak, 5 additional coronaviruses have been discovered in humans, most recently the novel coronavirus COVID-19, believed to have originated in Wuhan, Hubei Province, China. SARS-CoV and MERS CoV are particularly pathogenic in humans and are associated with high mortality [2, 3].

The world is now suffering from this global pandemic which has killed millions of people worldwide [4, 5]. As evidence shows, all people in the world are susceptible to this viral respiratory tract disease, although the impact is different depending on several socio-demographic, economic, and other infrastructural differences. There are no any proven pharmacological treatments developed for the disease until now, although a number of trials are currently underway by scientists across the globe. However, COVID-19 vaccines are developed within the shortest period in the history of vaccine production and now become available. Ethiopia also received AstraZeneca vaccines manufactured by Serum Institute of India (SII) on 6 March 2021 [6, 7]. However, there are scientifically accepted and recommended prevention measures against COVID-19 infection such as social distancing, frequent hand washing, use of face mask, and proper use of alcohol-based hand rubs or sanitizers [810].

Ethiopia is at high risk for the introduction and spread of the novel coronavirus disease (COVID-19) and the effect might be devastating because of the multiple health challenges the country already faces: rapid population growth and increased movement of people; existing endemic diseases, such as human immunodeficiency virus, tuberculosis, malaria and increasing incidence of non-communicable diseases [11]. Although some parts of the world are returning to pre COVID levels of engagement, the risk of the pandemic is continued and becomes a global challenge [12]. According to the September 2, 2021 Worldometer report, currently India and South Africa became the number one affected countries from Asian and African countries respectively [13]. Prevention practices are critical to combat the spread of Coronaviruses (CoVs) [9]. Poor prevention practices can lead to economic, social, and political crisis, and increased risk of death. The benefits of COVID-19 prevention, particularly in the developing setting like Ethiopia are invaluable because of the deprived health system [11, 14, 15].

To contain the pandemic, the country established a National Ministerial Committee and the government declared a state of emergency on April 8, 2020. On March 16, 2020, the committee released guidelines that included: 1) “A 14 days quarantine of passengers (travelers) in isolated centers; 2) Ethiopian Airlines to stop flying to 30 countries: 3) regulating the market to avoid unethical exploitation of the situation:4)stopping religious gatherings; 5)avoiding public overcrowding; 6) strictly refraining from harassing foreign nationals; 7) strict adherence to self- prevention and protection; 8) medical professional training;9) facilitating the acquisition of testing facilities; 10) temporarily closing of night clubs and bars; 11) regulating market to avoid unethical exploitation of the situation; and 12) supporting regions preparedness to contain the disease” [8, 11, 15].

In this study, healthcare workers and key informants in the community including local leaders were interviewed either individually or as part of focus groups to share their perceived barriers to COVID-19 prevention measures. This is helpful from the view of the following perspectives. Healthcare workers are the frontline in battling the spread infection as a whole [16]. Secondly, community leaders have a great role in the prevention of COVID-19 infection in the community [17].

The basic protective measures against COVID-19 including distancing, personal protective equipment, and handwashing as noted above are poorly practiced in the community of South Gondar Zone, along with the above scientific explanations, controlling the spread of infection is essential to preventing outbreaks of COVID-19 [18]. Basic protective measures against the new coronavirus include staying at home, washing hands with soap and water, frequently, using alcohol-based hand rub or washes, use of personal protective equipment, and keeping physical/social distance [9, 15, 19]. Thus, the implementation of these practices to reduce the spread of COVID-19 would be challenging in Ethiopia. Consequently, the perception of health extension workers and community leaders as a key informant are important to underpin the prevention of COVID-19 Infection [11, 20]. In response, the present qualitative study was designed to explore the community risk perception about COVID-19 and the perceived barriers to practice recommended prevention measures among community key informants and other community member’s in South Gondar Zone, North west Ethiopia.

Methods and materials

Study area and period

This study was conducted on purposely selected Woredas (the lowest administrative areas called woreda’s or districts in Ethiopia, government structure which form zone [21] of South Gondar Administrative Zone (Worata, Libokemkem (Adiszemen) and Guna Begemidir woreda (Kimirdingay) from May 15 to June 01, 2020. There are eight primary and one comprehensive specialized hospital and more than 187 health centers in the zone. According to the 2007 E.C population census report, the total population of the zone is around 2,578,906. Currently, there is one isolation center prepared at Atse Seyife Yared Health center and one quaratine center at Debre Tabour University. There is also one treatment center at the zonal level. However, COVID-19 treatment centers are not still established at the woreda level.

Study design

A qualitative study using a phenomenological approach was used to explore the perceptions, thinking, feelings, and experience of community members and health extension workers on a specific topic to explore the community risk perceptions and barriers related to the practice of COVID-19 prevention measures in the community. This study follows COREQ guidelines for reporting qualitative studies [22].

Inclusion criteria

  • ✓ People resided for at least six months in the area

  • ✓ People with age greater than 18 years

  • ✓ Community key informants (health extension workers, Women, health development armies, and religious leaders)

  • ✓ Health extension workers who have been working more than two years in the respective sites

Participants of the study and sampling procedures

The participants of this qualitative study were purposely selected community members and health extension workers. The community key informants (Health extension workers, women health development armies, and religious leaders) were selected for in-depth interviews with the assumption of having detail information about the issue in each community, while other community members were selected for focus group discussions in two rounds (7 participants in each round) at the selected woreda’s. We determined the sample size based on a theoretical saturation point in data collection time when new data no longer bring additional information to the research question. Therefore, the interview process was continued until that point was obtained. Finally, a total of 9 community key informants for in-depth interview and 14 individuals from the community were participated in focus group discussions.

Data collection tools and procedures

In-depth interviews and focus group discussions were conducted using a semistructured in-depth interview and focus group discussion guide to facilitate the interviews (see S2 and S3 Files). The guide was developed by the research team by reviewing similar literatures on the area. It was first developed in English and then translated to the local language (Amharic) to facilitate communication with participants.

The guides were focused on the community’s experiences with the practice of the recommended prevention methods of COVID-19, their risk perceptions on acquiring the disease, and the barriers to practice it in the community. All interviews and discussions were tape-recorded and written notes were also taken during the interviews. Participants of the study were selected with the help of the health local leaders. After we obtained informed consent to participate, an appropriate place and time for an interview and focus group discussion was arranged in a private setting. Two public health professionals who had a Master of public Health in health education and Epidemiology collected the data with the assistance of two note takers. Interviewers and facilitators were fluent in written and spoken Amharic and English language. All interviews were conducted within the community setting and lasted 30–60 minutes.

The transferability of the findings was established by collecting data on randomly selected woreda’s in the administrative zone with community key informants who are representatives of the community and having detail information about the people in their surroundings. This helped to get more information from different perceptions of the community with different socio-demographic and cultural experiences. To maintain the validity of the findings, the investigators developed a rapport with participants who were participated in the study. Credibility was maintained through participant checking during in-depth interviews and focus group discussions, and through feedback of findings at the end of the study from whom the data was taken. Keeping a record with information about imitation was enhanced conformability. The dependability of data was maintained by taking the depth of information until reaching the data saturation point.

Data analysis procedure

The qualitative data collected from in-depth interviews and focus group discussions were transcribed verbatim and translated into English language and thematically analyzed using open code software version 4.02 by relistening the tape recorder several times and reading the field notes line by line. The transcripts were carefully read and entered in to open code software. Transcripts and translations were cross-checked for accuracy and consistency by two independent persons. First, repeated responses for each question were identified, and then similar responses and grouped into codes. The coding process was continued until the data was exhausted. Then, the codes were categorized and themes were merged.

Data quality assurance

To maintain data quality, the supervisor and data collectors were trained for two days on the basic principles of data collection, study overview, and how to do other related activities during data collection by the principal investigator. Strict daily supervision of the data collection process were maintained throughout the data collection period. One supervisor was responsible for one study site. The data collectors were debriefed each day after the data collection by the supervisors.

Ethical approval and consent to participate

Ethical approval letter was obtained from Debre Tabor University. Official letter of co-operation was written to community leaders and health extension workers to obtain their co-operation in facilitating the study. Oral informed consent was obtained from each participant prior to data collection after information on the study was explained to them (see S1 File). This is because the study is just a qualitative research which did not have any intervention /clinical trial and did not have follow-ups. In addition, some of the participants were illiterate, so taking oral consent was sufficient after giving a detail explanation on the aim of the study to the participants (see the details of the study information sheet in S1 File). The ethical committee was approved the oral consent procedure. Confidentiality of information was assured by excluding names and identification in the interviews. In-depth interviews and focus group discussions were conducted by maintaining WHO recommendations for social distancing and use of appropriate personal protective equipment’s.

Results

Socio-demographic characteristics of study participants

The table below describes the socio-demographic characteristics of focus group discussions and in-depth interview participants for this particular qualitative study. A total of 9 in-depth interviews and 2 focus group discussions were conducted. The age of the participants ranged from 24 to 70 years with the median age of 46 years. The majority 14 (60.9%) of the participants were females. Among the participants of in-depth interview, 2 were health extension workers, 5 were women health development armies, and 2 were religious leaders. About 19 (82.6%) were orthodox religion followers while the rest were Muslims. Regarding marital status, most 14 (60.9%) of the participants were married while the rest were single. The majority 17 (73.9%) of the participants were from rural areas (Table 1).

Table 1. Socio-demographic characteristics of study participants for in-depth interview and focus group discussion in South Gondar Zone, Northwest Ethiopia, 2020.

Characteristics Frequency (n = 23) Percentage
Age group
<30 3 13.0
30–39 5 21.7
40–49 4 17.4
50–59 5 21.7
≥60 6 26.1
Home residence
Rural 17 73.9
Urban 6 26.1
Educational status
Illiterate 5 21.7
Primary education completed 3 13.0
Secondary education completed 6 26.1
College and above completed 9 39.1
Religion
Orthodox 19 82.6
Muslim 4 17.4
Marital status
Married 14 60.9
Single 9 39.1
Occupational status
Farmer 9 39.1
Government employee 6  26.1
House wife 3  13.0
Merchant 5 21.7
Role in the community
  Health extension worker 2 8.7
 Women health development army 5 21.7
  Religious leader 2 8.7
  Other community member* 14 60.9

Key: * = peoples selected for focus group discussion from the community.

Risk perception and barriers for the practice of COVID-19 prevention methods

Three main themes (Personal factors, Socio-demographic & economic related factors, cultural and religious related factors) and five categories (Lack of knowledge & awareness, Socio-demographic, economic, cultural, and religious related barriers) were emerged from the narrations of the participants regarding the risk of acquiring of COVID-19 and perceived barriers for the practice of prevention measures (see S4 File).

Personal related barriers

Lack of knowledge and awareness about COVID-19 infection

As most of the participants’ described, there were various reasons mentioned for not practicing COVID-19 prevention measures in the community. One of the major reasons stressed by almost all participants for not practicing COVID-19 prevention measures was lack of knowledge and awareness about risk factors, signs, and symptoms of the disease. Most of the focus group discussion participants did not hear about the prevention measures as well as the clinical features of the disease.

“I heard this new disease from the health extension worker, however, I did not understand about the disease. I do not know, it will infect me or not….” (A 32 -years-old female FGD participant)

“I heard the name of the disease which is called “Corona’. I did not know about its characteristics. There was no such disease in our country.” (A 52 -years-old female FGD participant)

As some participants described, there is a lack of information access about COVID-19, particularly for the rural community, still some participants did not hear about the disease, while some others heard only the coming of new disease or epidemic only but they did not hear about the disease clinical features and prevention measures.

“I did not hear about this new disease which you called Corolla or Corona. I heard it know from you. As you know, my house is far from the health post. Unless the health extension worker comes to our Kebele, I could not hear anything about health.” (A 60 -years-old women health development army)

“I heard the name Corona virus disease through a telecom message in my phone. However, I did not understand about the prevention methods” (A 45 -years-old FGD participant)

As narrated by the participants, some heard about the prevention methods, but they did not understand how to practice it. Even some participants mentioned the recommended prevention measures like hand washing with soap and water, maintaining, physical distancing, and staying at home, but none of them have detail information about how to practice them.

I have television and I heard the prevention methods of corona virus, but I am not aware and clear about its importance and how to practice it.” (A 35 -year-old women, health development army)

Socio-demographic and economic related barriers

Almost all participants explained that it is very difficult to practice all prevention measures of COVID-19, mainly it is difficult to stay at home, although it is essential to keep oneself from COVID-19 infection since almost all people need their daily consumption from their daily work. Therefore, it will cause hunger and another social chaos or distraction if it is obliged to stay at home. They explained as the stay-at-home policy could not be wrought for low-income countries such as Ethiopia.

“I myself could not stay at home because I could not get my daily foods because I am a daily worker.” A 28 -years-old FGD participant

“Ohhh…. How can we stay at home? For how many days? It is unthinkable, we all have work outside our homes.” A 32 -years-old FGD participant

Some of the participants relate the disease to demographic factors like age and residence. They perceived as the disease could not infect children and young’s and some perceived as the disease will affect the urban population. As a result of these mentioned barriers, people fail to practice the prevention methods.

“---I think the disease does not affect young people. Therefore, I will not be at risk of this disease. Thus I do not afraid and care about it too much” A 24 -years-old FGD participant

“As I heard, the disease transmission will be fast in cold environment than hot areas. We are living in a hot climatic areas, so the disease will not affect us that much.” (A 40 -year-old health extension worker)

“…‥I am 70 years old, and I have heart problems. My child is a college student and he told me as I am at risk of this disease if it comes to our village …” (A 70 -years-old FGD participant)

As the participants explained, most of them did not have adequate money and other resources for their daily lives. As they narrated, those individuals who have money will buy their essential goods for a month or more than that and they can stay at home. However, those who get their income from their daily work could not afford that and could not stay at home.

“I think staying at home is very difficult for most people in our country since most people could not get their daily consumption, rather the impact will be worse than the effect of the disease.” (A 46 -year-old Women, health development army)

As the participants described, there is no even access to get soap for practicing hand washing mainly for the rural people. They did not get also alcohol-based hand rub/ sanitizer/.

“I could not get adequate soap for my family to regularly wash our hands. It is costly for me and I could not afford to buy it. I do not know hand sanitizer, I only heard from you now.” (A 39 -years-old FGD participant)

Among the participants, the majority of them were from rural areas. As they said, their being in rural and remote areas makes them to not to access updated information’s about the disease since they are far from the health facilities and some life in hard-to-reach areas so that their frequent contact is very low to the health care providers.

“I live in very remote area. Unless I come to a health facility, no one can come to my village and tell me about the disease since there is not transport access to our village.” (A 46 years old FGD participant).

“I lived in a rural area so I faced many difficulties when I came to this now because of the long distance. Since there is no road transport access.” A 52 -years-old FGD participant

The participants also explained that the absence of an educated person in the household would have a significant role for not practicing the prevention methods. Since it is difficult to understand the disease characteristics.

Cultural and religious related barriers

The other important barrier mentioned by the participants was considering the disease as not that much serious and even some understand as it is the disease of those who eat wild animals which are not allowed to be eaten in the bible.

“…As I heard from other people, corona will infect those who eat wild animals but not us.” (A 38 -year-old health extension worker)

The most frequent reason reflected by the participants for not practicing COVID-19 prevention measures was that they trusted in their religion and did not affect those who had a strong religious practice. As they described, if we follow the right principles of religion and strongly believe on GOD, they will not be affected by the disease. All participants believe that the disease comes due to our sin and GOD wants to teach his power to the world.

“…I am sure that this disease is due to our sin and the GOD wishes to teach us by this disease and he just shows his supreme power to the world as no one can do anything without the will of GOD”. (A 50-year-old religious leader)

“…if you strongly believe in the power of GOD, this disease will not infect you.” (A 65 year’s FGD old participant)

“There were several predictions that this kind of epidemic will occur from our ancestors. Therefore, the disease is due to in human acts like homosexuality, racism.” (A 55 years-old religious leader)

“If I virus infects me, I will go to use holy water and I will pray. I will not prefer to go to the health facilities since there is no any medical treatment till know.” (A 45-year-old participant, FGD said).

As the participants said, almost all participants were trusted with the use of traditional treatments prepared from different herbal plants. As the participants believed that the disease could be healed by common traditional treatment modalities. When they were asked also what they will do if they have the disease, they said as they will use these traditional treatments prepared by the local traditional healers from different plant leaves and roots and to use holy water. Most of the participants have a strong belief on the use of herbal medications and spiritual treatment options for treating corona virus than modern medical care. This all-mentioned reason may consider as barriers for practicing COVID-19 prevention measures.

“I think the herbal medication which we used for common cold will be effective to treat corona since it has similar characteristics.” (A 40-year-old participant, FGD said)

“I think this disease is due to our sin, so praying and going to use holy water is the only option we have to do”. (A 68 year-old woman, health development army)

When the participants asked about their communities’ perception about the disease, there are different beliefs that made to not practice COVID-19 prevention measures. One thing that was mentioned was that their perception that the disease does not come from their locality. They believe that the government should close all boarders and should test all those who came from abroad, otherwise they think as our prevention could not have any effect on the disease.

“…people in my community believe that the disease does not come from our village and they strongly recommend the government to control those who come from abroad.” (A 57 -year-old FGD participant)

“In our community we have a strong social interaction and most of the time we live together and we meet for different social gatherings like mourn, wedding, Idir, Ikub, and even we drink coffee together. In addition, we do not want to eat alone, we eat together by sharing what we have in our hands, so this is very challenging to stop in a short period of time. (A 64 -years-old FGD participant)

“I think it is very challenging to practice prevention measures because our way of living is difficult to bring behaviour change. If someone tries to practice, some others are so careless. Therefore, one practice may not be enough and does not give a guarantee unless all other people surrounding you practice it.” (A 63 -year-old women, health development army)

“As I think, most of us try to practice, but sometimes we forget it and we do our normal part of life since we do not have such culture before.” (A 50 -year-old religious leader)

Some of the participants believe that the disease could not affect people living in very hot areas. As a result, some carelessness is observed in practicing COVID-19 prevention measures.

As you know, we live in hot area and the people in my village believe that the disease cannot come to hot areas, the disease cannot survive in hot areas…” (A 26 -years-old FGD participant)

Discussion

As evidence shows, the proper practice of the recommended prevention methods of COVID-19 is an effective and the only measure to control the spread of the pandemic [10, 14, 18]. However, the practice of such prevention measures is not consistent from place to place and peoples usually are reluctant to practice mainly in Ethiopia, although efforts are made by the government [11, 15, 23], so we tried to explore the perceived barriers for the practice of COIVID-19 prevention measures and community risk perception on the disease focusing on both rural and urban settings. Our study revealed that most community members perceived as they are at risk of acquiring COVID-19 infection, but lack of knowledge and awareness, socio-demographic, economic, cultural, and religious factors affect them to consistently practice prevention measures. The findings are similarly reported in other similar studies conducted in different regions of Ethiopia [17, 2427].

Regarding social distancing, our study revealed that most people are not that much aware of practicing social distancing. As most said, they did not understand the concept of social distancing, how much distance is allowed for protection in COVID-19. People’s way of living has a significant role in the implementation of COVID-19 prevention measures since most people in Ethiopia are living together in closed environments. Thus, the peoples have difficulty to maintain their social distancing. This finding is in line with a study conducted in other parts of the country in which lack of awareness is a significant contributor for improper practice of COVID-19 prevention measures [17, 25]. Lack of access to information is also a factor mentioned in our study as most people could not get updated information about the disease risk factors and prevention methods. This finding is consistent with a study conducted in Northwest Ethiopia which found the overall rate of information exposure about COVID-19 was less than 50 percent [24].

The other important recommended and effective prevention measure is stay at home; however, our findings showed that it is a very difficult preventive measure to practice since most people live in hand-to—to—mouth way of life so that they need to get their daily consumption through daily work otherwise they will face hunger. As a result of this, most people cannot stay at home. As Ethiopia is one of the low-income countries in the world with very young population and most of the people are living in the traditional way of life which is risky for contagious diseases like COVID-19. As a result of these, most people live together in a clustered environment, approximately 4–8 people in a single room. The finding is in line with other studies conducted in Ethiopia [11, 15, 28].

In our study, cultural and religious factors were mentioned as barriers for the practice of COVID-19 prevention measures. There are several strong religious and cultural practices in Ethiopia which interact with people in different social activities like mourning, wedding, Idir, Ikub, and coffee ceremonies. Therefore, it is a challenging task for the government to change people’s behaviour to practice prevention measures. Culturally, there are a number of practices which need public gathering in Ethiopia. Therefore, the presence of such strong cultural norms, myths, and beliefs affect peoples to practice COVID-19 prevention measures properly [26].

Most people also do not have access to hand washing facilities. Some are unable to get soap due to financial limitations while some others do not have access to water supply.

Our study also revealed that several religious barriers are mentioned as reasons for not practicing COVID-19 prevention measures. These barriers mentioned were strong religious believers which people spend most of their time at morning and evening at churches and mosques which make them to expose to each other. Peoples are reluctant to stop to go to public gathering areas like churches and mosques. There is a strong belief in the community that this disease could only be tackled through keeping religious activities since most of the society believe that the disease is caused due to people’s sin as GOD’s punishment. The findings are similar to other study findings in Ethiopia in which strong religious practices make people not to trust on prevention methods, rather prefer to pray together and strongly engaging in other religious activities to combat the pandemic [26, 28, 29]. This perception may also become challenges in the acceptance of COVID-19 vaccine if supplies become available in the area unless community sensitization to dispel myths and misconceptions. Still, the acceptance of the vaccine is low in Ethiopia (31.4%) [30].

Our study implies that, although community members perceived as they will be at risk of acquiring the disease, their practice of recommended prevention methods is nil, which is also a national problem encountered in the country [11, 15]. Similarly as a study in Gondar city found, the overall prevalence of good adherence towards COVID-19 prevention measures was 51.04% [28].

Strength of the study

Based on the researcher knowledge, this study is the first qualitative study in the area which explored the risk perceptions of the community and the perceived barriers to the practice of COVID-19 prevention measures from community key informants and other community member’s perspective using in-depth interviews and focus group discussions.

Limitations of the study

Since the majority of the participants were from a rural areas, the residential status may be a determinant of the perceived barriers.

Conclusion

Lack of knowledge and awareness about the disease, socio-demographic barriers, presence of strong cultural and religious practices, perceiving that the disease does not affect the young, misinformation about the disease, and lack of trust on the prevention measures were the major perceived barriers for the practice of COVID-19 prevention measures explored in this study. Our findings show the need for creating community awareness and education programs about the prevention measures of COVID-19, and it is essential to increase diagnostic facilities with strong community-based surveillance to control the transmission of the pandemic. Additionally, strict measures should be taken nationally to those who are reluctant to practice the methods to save the lives of the majority.

Supporting information

S1 File. Study information sheet for participants of in-depth interview and focus group discussion.

(PDF)

S2 File. In-depth interview guide.

(PDF)

S3 File. Focus group discussion guide.

(PDF)

S4 File. Themes and categories (subthemes) developed from the narration of in-depth interviews and focus group discussion.

(PDF)

Acknowledgments

Authors would like to acknowledge data collectors, supervisors, and participants for focus group discussions and in-depth interviews.

Data Availability

All relevant data are within the paper and its Supporting Information files.

Funding Statement

The author(s) received no specific funding for this work.

References

  • 1.Huang C., et al., Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. The lancet, 2020. 395(10223): p. 497–506. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 2.Chan J.F., et al., A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: a study of a family cluster. Lancet, 2020. 395(10223): p. 514–523. doi: 10.1016/S0140-6736(20)30154-9 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Lu R., et al., Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding. Lancet, 2020. 395(10224): p. 565–574. doi: 10.1016/S0140-6736(20)30251-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.Abrahim S.A., et al., Time to recovery and its predictors among adults hospitalized with COVID-19: A prospective cohort study in Ethiopia. PLoS One, 2020. 15(12): p. e0244269. doi: 10.1371/journal.pone.0244269 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 5.Hailay A., et al., The burden, admission, and outcomes of COVID-19 among asthmatic patients in Africa: protocol for a systematic review and meta-analysis. Asthma Res Pract, 2020. 6: p. 8. doi: 10.1186/s40733-020-00061-x [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 6.Ethiopia gears up for Covid vaccine drive as fist doses arrive Africa—World [Internet]. Ahram Online; [cited March 23, 2021]. Available from: https://english.ahram.org.eg/NewsContent/2/0/405482/World/0/Ethiopia-gears-up-for-Covid-vaccine-drive-as-fist. aspx. Accessed June 08, 2021.
  • 7.Coronavirus (COVID-19) Vaccinations. (Accessed June 8, 2021) 10.1038/s41562-021-01122-8. [DOI]
  • 8.Shigute Z., et al., COVID-19 and balance in access to health care in Ethiopia. Clin Epidemiol Glob Health, 2021. 9: p. 1. doi: 10.1016/j.cegh.2020.05.013 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 9.Wu D., et al., The SARS-CoV-2 outbreak: What we know. Int J Infect Dis, 2020. 94: p. 44–48. doi: 10.1016/j.ijid.2020.03.004 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 10.Malm A. Corona, Climate, Chronic Emergency: War Communism in the Twenty-First Century: Verso; 2020.
  • 11.Zikargae M.H., COVID-19 in Ethiopia: Assessment of How the Ethiopian Government has Executed Administrative Actions and Managed Risk Communications and Community Engagement. Risk Manag Healthc Policy, 2020. 13: p. 2803–2810. doi: 10.2147/RMHP.S278234 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 12.Tomar A. and Gupta N., Prediction for the spread of COVID-19 in India and effectiveness of preventive measures. Sci Total Environ, 2020. 728: p. 138762. doi: 10.1016/j.scitotenv.2020.138762 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 13.Worldometer report (accessed June 8, 2021) https://www.worldometers.info/coronavirus/.
  • 14.Dahab M., et al., COVID-19 control in low-income settings and displaced populations: what can realistically be done? Confl Health, 2020. 14: p. 54. doi: 10.1186/s13031-020-00296-8 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 15.Ayenew B. Challenges and opportunities to tackle COVID-19 spread in Ethiopia. Journal of PeerScientist. 2020;2(2):e1000014. [Google Scholar]
  • 16.Gan W.H., Lim J.W., and Koh D., Preventing Intra-hospital Infection and Transmission of Coronavirus Disease 2019 in Health-care Workers. Saf Health Work, 2020. 11(2): p. 241–243. doi: 10.1016/j.shaw.2020.03.001 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 17.Mechessa D.F., et al., Community’s Knowledge of COVID-19 and Its Associated Factors in Mizan-Aman Town, Southwest Ethiopia, 2020. Int J Gen Med, 2020. 13: p. 507–513. doi: 10.2147/IJGM.S263665 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 18.Kraemer M.U., et al., The effect of human mobility and control measures on the COVID-19 epidemic in China. Science, 2020. 368(6490): p. 493–497. doi: 10.1126/science.abb4218 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 19.Gebremariam B.M., et al., Epidemiological characteristics and treatment outcomes of hospitalized patients with COVID-19 in Ethiopia. Pan Afr Med J, 2020. 37(Suppl 1): p. 7. doi: 10.11604/pamj.supp.2020.37.7.24436 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 20.Asemahagn M.A., Factors determining the knowledge and prevention practice of healthcare workers towards COVID-19 in Amhara region, Ethiopia: a cross-sectional survey. Trop Med Health, 2020. 48: p. 72. doi: 10.1186/s41182-020-00254-3 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 21.Ayele, Zemelak. "Local government in Ethiopia: still an apparatus of control?". Law, Democracy & Development. "It also authorised each ethnic group to establish self-government starting from woreda (district) level.15 (2011). ISSN 2077-4907. ".
  • 22.AllisonTong Peter Sainsbury and Craig Jonathan. Consolidated criteria for repor ting qualitative research (COREQ): a 32-item checklist for inter views and focus groups. Inter nationa l Jour nal for Quality in Health Care; Volume 19, Number 6: pp. 349–357:: http://intqhc.oxfordjournals.org/content/19/6/349. [DOI] [PubMed] [Google Scholar]
  • 23.Asnakew Z., Asrese K., and Andualem M., Community Risk Perception and Compliance with Preventive Measures for COVID-19 Pandemic in Ethiopia. Risk Manag Healthc Policy, 2020. 13: p. 2887–2897. doi: 10.2147/RMHP.S279907 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 24.Tamiru A.T., et al., Community Level of COVID-19 Information Exposure and Influencing Factors in Northwest Ethiopia. Risk Manag Healthc Policy, 2020. 13: p. 2635–2644. doi: 10.2147/RMHP.S280346 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 25.Muluneh Kassa A., Gebre Bogale G., and Mekonen A.M., Level of Perceived Attitude and Practice and Associated Factors Towards the Prevention of the COVID-19 Epidemic Among Residents of Dessie and Kombolcha Town Administrations: A Population-Based Survey. Res Rep Trop Med, 2020. 11: p. 129–139. doi: 10.2147/RRTM.S283043 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 26.Kebede Y., et al., Myths, beliefs, and perceptions about COVID-19 in Ethiopia: A need to address information gaps and enable combating efforts. PLoS One, 2020. 15(11): p. e0243024. doi: 10.1371/journal.pone.0243024 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 27.Haftom M., et al., Knowledge, Attitudes, and Practices Towards COVID-19 Pandemic Among Quarantined Adults in Tigrai Region, Ethiopia. Infect Drug Resist, 2020. 13: p. 3727–3737. doi: 10.2147/IDR.S275744 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 28.Azene Z.N., et al., Adherence towards COVID-19 mitigation measures and its associated factors among Gondar City residents: A community-based cross-sectional study in Northwest Ethiopia. PLoS One, 2020. 15(12): p. e0244265. doi: 10.1371/journal.pone.0244265 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 29.Asmelash D., et al., Knowledge, Attitudes and Practices Toward Prevention and Early Detection of COVID-19 and Associated Factors Among Religious Clerics and Traditional Healers in Gondar Town, Northwest Ethiopia: A Community-Based Study. Risk Manag Healthc Policy, 2020. 13: p. 2239–2250. doi: 10.2147/RMHP.S277846 [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 30.Belsti Y, Gela YY, Akalu Y, Dagnew B, Getnet M, Abdu Seid M, et al. Willingness of Ethiopian Population to Receive COVID-19 Vaccine. J Multidiscip Healthc. 2021;14:1233–1243 10.2147/JMDH.S312637 [DOI] [PMC free article] [PubMed] [Google Scholar]

Decision Letter 0

Amy Michelle DeBaets

13 Apr 2021

PONE-D-21-07870

Perceived Barriers for the Practice of Covid-19 Prevention Measures in Northwest Ethiopia: A Qualitative Study

PLOS ONE

Dear Dr. Tesfaw,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

In your revised version of your article, please review and respond to each comment from the reviewers. We look forward to receiving your revised version.

Please submit your revised manuscript by May 28 2021 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols.

We look forward to receiving your revised manuscript.

Kind regards,

Amy Michelle DeBaets, PhD

Academic Editor

PLOS ONE

Journal Requirements:

When submitting your revision, we need you to address these additional requirements.

1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at

https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and

https://journals.plos.org/plosone/s/file?id=ba62/PLOSOne_formatting_sample_title_authors_affiliations.pdf

2. We suggest you thoroughly copyedit your manuscript for language usage, spelling, and grammar. If you do not know anyone who can help you do this, you may wish to consider employing a professional scientific editing service.  

Whilst you may use any professional scientific editing service of your choice, PLOS has partnered with both American Journal Experts (AJE) and Editage to provide discounted services to PLOS authors. Both organizations have experience helping authors meet PLOS guidelines and can provide language editing, translation, manuscript formatting, and figure formatting to ensure your manuscript meets our submission guidelines. To take advantage of our partnership with AJE, visit the AJE website (http://learn.aje.com/plos/) for a 15% discount off AJE services. To take advantage of our partnership with Editage, visit the Editage website (www.editage.com) and enter referral code PLOSEDIT for a 15% discount off Editage services.  If the PLOS editorial team finds any language issues in text that either AJE or Editage has edited, the service provider will re-edit the text for free.

Upon resubmission, please provide the following:

  • The name of the colleague or the details of the professional service that edited your manuscript

  • A copy of your manuscript showing your changes by either highlighting them or using track changes (uploaded as a *supporting information* file)

  • A clean copy of the edited manuscript (uploaded as the new *manuscript* file)

3. Please specify in your ethics statement:

a) whether the ethics committee approved the verbal/oral consent procedure,

b) why written consent could not be obtained, and

c) how verbal/oral consent was recorded.

4. When reporting the results of qualitative research, we suggest consulting the COREQ guidelines: http://intqhc.oxfordjournals.org/content/19/6/349. In this case, please consider including more information on the number of interviewers, their training and characteristics; and please provide the interview guide used.

5. Please include a copy of Table 2 which you refer to in the Results section of your text.

6. Your ethics statement should only appear in the Methods section of your manuscript. If your ethics statement is written in any section besides the Methods, please delete it from any other section.

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Partly

Reviewer #2: Yes

**********

2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: N/A

Reviewer #2: Yes

**********

3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: No

Reviewer #2: Yes

**********

4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: No

Reviewer #2: Yes

**********

5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: The quotes presented in this paper are very valuable, however, given that they are from nearly a year ago it would be useful to place them into context with the state of the pandemic now. Have the cases become unmanageable, likely as a result of the identified barriers, or was the government about to step up and provide a widespread educational campaign/provide mask, etc.? The paper, in particular the methods section, is hard to follow. The journal is likely able to help with grammar, but there are also several typos and the methods section is repetitive without making the recruitment strategy clear.

For example:

1. For the “source and study population” section, it is noted that “all people residing in South Gondar zone…were the source populations…” But I imagine individuals recruited for the in-depth interviews were patients in the clinic for the day? Either way the specific way they were targeted/recruited needs to be specified.

2. Similarly, how were the members for the focus group recruited? While the sample size for qualitative studies is generally low, those in this study cover a large geographic region, large spread in age, and professions. For this reason, it would be useful to provide some kind of indication of who is saying what quote and potentially a table of frequencies per theme/category…maybe also separate this by community member vs. key informants.

3. Please provide the interview guide

4. Why was the interview guide created in English? Are there subtleties in the native language that would provide different meaning?

Reviewer #2: Abstract: the last sentence of results is incomplete as same as the first one of conclusion.

Abstract/.conclusion: don’t repeat results as conclusion

Introduction: a short looking at current literature/previous studies improves the introduction.

Methods: don’t use future verbs

Methods: sampling method needs more exploration, it is to somewhat unclear in the current form.

Methods: as the majority of participants were from rural regions, it should be notes as a limitation considering that the residential status may be a determinant of perceived barriers.

Results: inserting a table including the main themes and sub-themes in the beginning of results is suggested.

Discussion: the first 2 paragraphs of discussion should e removed into introduction section. Start your discussion with brief presentation of main results.

Discussion: discussion section should be improved by providing some policy recommendation/applications of results to deal with the problem and improve the status.

**********

6. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: Yes: Mohammad Amin Bahrami

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2021 Sep 24;16(9):e0257897. doi: 10.1371/journal.pone.0257897.r002

Author response to Decision Letter 0


18 May 2021

Dear, Editor,

Greetings!

Thank you very much for all the comments provided regarding our manuscript entitled “Perceived Barriers for the Practice of Covid-19 Prevention Measures in Northwest Ethiopia: A Qualitative Study” which are fully accepted and included in the revised version. I have accordingly made necessary revisions on the paper following the comments provided from the reviewers and editor. I also attached the themes and categories (Sub-themes) as supporting information file 4 and in-depth interview and Focus group discussion guides as supporting information file 2&3 for the reviewers based on their request. in addition I attached the study information sheet and consent form as supporting information file-1. For your kind consideration, please find a point by point response to the comments in the next page of this letter and a submitted new revised version of the manuscript.

All new changes have been highlighted in dark blue in the main document in order to facilitate review.

I hope that you will find the edits as per your expectation and I look forwards to hear from you

soon.

Yours Sincerely,

Aragaw Tesfaw (MPH, Epidemiology)

Lecturer, Department of Public health

College of health sciences, Debre Tabor University

Email: aragetesfa05@gmail.com

Phone: 251921743820

I. Point by point responses to editor comments

1. Please ensure that your manuscript meets PLOS ONE's style requirements, including those for file naming. The PLOS ONE style templates can be found at

https://journals.plos.org/plosone/s/file?id=wjVg/PLOSOne_formatting_sample_main_body.pdf and

https://journals.plos.org/plosone/s/file?id=ba62/PLOSOne_formatting_sample_title_authors_affiliations.pdf

- Author Responses: corrected /edited based on the given editor comment and we prepared the manuscript based on the PLOS ONE author guide line.

2. We suggest you thoroughly copyedit your manuscript for language usage, spelling, and grammar. If you do not know anyone who can help you do this, you may wish to consider employing a professional scientific editing service.

- Author Reponses: We invited English language editor for grammar edition and she corrected grammatical issues accordingly based on the recommendation. in addition we used on line grammar editing services.

Upon resubmission, please provide the following:

• The name of the colleague or the details of the professional service that edited your manuscript

Author Reponses: the name of the colleague who edit the grammar was Emaway Belay, she is health education, promotion and Behavioral science expert and she has master of public health

• A copy of your manuscript showing your changes by either highlighting them or using track changes (uploaded as a *supporting information* file)

Author Reponses: All new changes have been highlighted in dark blue in the main document and other requested information’s are uploaded as supporting information files

• A clean copy of the edited manuscript (uploaded as the new *manuscript* file)

Author Reponses: The edited manuscript is uploaded as Manuscript file

3. Please specify in your ethics statement:

a) Whether the ethics committee approved the verbal/oral consent procedure,

Author Reponses: Yes! The ethical committee was approved the oral consent procedure

b) Why written consent could not be obtained, and

Author Reponses: the study is just a qualitative research which did not have any interventions /clinical trial and did not have follow ups. In addition some of the participants were illiterate so oral consent was appropriate to take in our study after giving a detail explanation on the aim of the study to the participants (see the detail of study information in supporting information file 1).

c) How verbal/oral consent was recorded.

Author Reponses: What we’re doing is just we read the study information sheet which deals about the study objectives, the rights and confidentiality of the information obtained from participants, they were agreed to participate in the study then we included them to the study and we record their sayings (see the detail of study information in supporting information file 1) .

4. When reporting the results of qualitative research, we suggest consulting the COREQ guidelines: http://intqhc.oxfordjournals.org/content/19/6/349. In this case, please consider including more information on the number of interviewers, their training and characteristics; and please provide the interview guide used.

Author Reponses:

- We used COREQ guidelines in this qualitative study and we attached the interview guide as supporting information file 2&3

- There were two interviewers and two note takers who conducted the FGD and in-depth interviews. The interviewers are public health professionals who have master in public health specialties and had experience in qualitative research.

5. Please include a copy of Table 2 which you refer to in the Results section of your text.

Author Reponses: we are now put a copy of Table 2 based on the comment (see supporting information file _4)

6. Your ethics statement should only appear in the Methods section of your manuscript. If your ethics statement is written in any section besides the Methods, please delete it from any other section.

Author Reponses: edited/corrected based on the comment

II. Point by point responses to the comments for reviewers

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Partly

Reviewer #2: Yes

________________________________________

2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: N/A

Reviewer #2: Yes

________________________________________

3. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: No

Reviewer #2: Yes

________________________________________

4. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: No

Reviewer #2: Yes

________________________________________

Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

5. Reviewer #1: The quotes presented in this paper are very valuable, however, given that they are from nearly a year ago it would be useful to place them into context with the state of the pandemic now. Have the cases become unmanageable, likely as a result of the identified barriers, or was the government about to step up and provide a widespread educational campaign/provide mask, etc.? The paper, in particular the methods section, is hard to follow. The journal is likely able to help with grammar, but there are also several typos and the methods section is repetitive without making the recruitment strategy clear.

For example:

1. For the “source and study population” section, it is noted that “all people residing in South Gondar zone…were the source populations…” But I imagine individuals recruited for the in-depth interviews were patients in the clinic for the day? Either way the specific way they were targeted/recruited needs to be specified.

Author Reponses: individuals recruited for the in-depth interviews were not patients (it was editorial error) in the clinic for the day rather they were purposely selected community key informants (women health development armies, Health extension workers and religious leaders) for In-depth interviews while the FGD participants were selected purposely from community members with the help of local Kebele leaders.

2. Similarly, how were the members for the focus group recruited? While the sample size for qualitative studies is generally low, those in this study cover a large geographic region, large spread in age, and professions. For this reason, it would be useful to provide some kind of indication of who is saying what quote and potentially a table of frequencies per theme/category…maybe also separate this by community member vs. key informants.

Author Reponses:

The FGD participants were selected from the community members with the help of local leaders in the study sites. The study is conducted in one administrative zone (South Gondar zone) and it is not a regional study. The Themes, categories and the main findings /selected quotes were putted in the supporting information file based on the comment.

(See supporting information file -4)

3. Please provide the interview guide

Author Reponses: edited/corrected as commented, we provide the interview guide as supporting information file 2&3

4. Why was the interview guide created in English? Are there subtleties in the native language that would provide different meaning?

Author Reponses:

The guide (IDI & FGD) was first developed in English language and then translated to the local language (Amharic) to facilitate communication with participants. Interviewers and facilitators were fluent in written and spoken Amharic and English language.

6. Reviewer #2: Abstract: the last sentence of results is incomplete as same as the first one of conclusion.

Abstract/.conclusion: don’t repeat results as conclusion

Author Reponses: edited/corrected based on the comments

Introduction: a short looking at current literature/previous studies improves the introduction.

Author Reponses: edited/corrected as commented

Methods: don’t use future verbs

Author Reponses: edited/corrected as commented

Methods: sampling method needs more exploration, it is to somewhat unclear in the current form.

Author Reponses: edited/corrected as commented

Methods: as the majority of participants were from rural regions, it should be notes as a limitation considering that the residential status may be a determinant of perceived barriers.

Author Reponses: edited/corrected as commented

Results: inserting a table including the main themes and sub-themes in the beginning of results is suggested.

Author Reponses: edited/corrected as commented (see supporting information file-4)

Discussion: the first 2 paragraphs of discussion should remove into introduction section. Start your discussion with brief presentation of main results.

Author Reponses: edited/corrected based on the comment

Discussion: discussion section should be improved by providing some policy recommendation/applications of results to deal with the problem and improve the status.

Author Reponses: edited/corrected based on the comment

7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: Yes: Mohammad Amin Bahrami

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

Attachment

Submitted filename: Response to Reviewers.docx

Decision Letter 1

Amy Michelle DeBaets

2 Jun 2021

PONE-D-21-07870R1

Community Risk perception and Barriers for the Practice of COVID-19 Prevention Measures in Northwest Ethiopia :  A Qualitative Study

PLOS ONE

Dear Dr. Tesfaw,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

==============================

Please address all additional comments from reviewer 1 in your revised submission.

==============================

Please submit your revised manuscript by Jul 17 2021 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols.

We look forward to receiving your revised manuscript.

Kind regards,

Amy Michelle DeBaets, PhD

Academic Editor

PLOS ONE

Journal Requirements:

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #1: (No Response)

Reviewer #2: All comments have been addressed

**********

2. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Partly

Reviewer #2: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: N/A

Reviewer #2: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception (please refer to the Data Availability Statement in the manuscript PDF file). The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: No

Reviewer #2: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS ONE does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: No

Reviewer #2: Yes

**********

6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: Thanks for taking the time to update the language and methods that now much more clearly explain the qualitative approach. A number of additional grammatical suggestions are provided below for the abstract, introduction, and methods as well as additional questions/comments. The results section and discussion can still use updating to the language to clarify meaning. I make a few suggestions below for the results section specifically. At the moment the discussion mostly serves to resummarize the results rather than place the findings in context of the ongoing pandemic. For example, can you more specifically state how these findings relate to other studies in Ethiopia, Africa, or other lower income countries? Coming from a public health group could you state a little more about how these findings could be used? Have other areas in the country/continent done a better job in implementing educational campaigns? Can you draw from other campaigns that have done a good job in communicating information to rural areas that may serve COVID-19? Could these findings drive approaches to the vaccine campaign once supplies become available? For example, how might religious beliefs impact the community from taking the vaccine?

Specific comments

Abstract

Methods: Community key informants and health extension workers were selected purposely for in-depth interviews and focus group discussion to [should this be “on” instead of “to”] maintaining WHO recommendations for social distancing and use of appropriate personal protective equipment [delete the 's.]

Specifically state the sample size number in the abstract.

FGD has not been defined in the abstract, this acronym is also not needed and could just state focus group discussions throughout the paper.

Results: Three main themes and five categories were emerged from… and 2 religious leaders were participated...[delete was] conducted among purposely selected community members. The age of the participants [delete was] ranged from 24 to 70 years…

For the last two sentences I would rearrange them so that it states- The major identified barriers for practicing COVID-19 prevention measures were the presence of strong cultural and religious practices, perceiving that the disease does not affect the young, misinformation about the disease, and “the” lack of trust on the prevention measures.

Conclusions: Socio-cultural, religious, and economics related barriers were identified from the participant’s narratives for the practice of COVID-19 prevention measures in south Gondar Zone. Our findings suggest the need to strengthen [delete “ing”] community

Background

The world is closely watching the outbreak of “the” respiratory illness…

The world is now suffering from this global pandemic which [has killed instead of “ kills”] millions

I would suggest the following change for this thought given the widespread availability of vaccines in parts of the world-There are not any proven pharmacological treatments [delete “and vaccines” … “until now”] although a number of trials are [consider adding “currently underway by scientist across” and delete “tested worldwide by several scientists in”] the globe. [Consider adding… “While several effective vaccinations are now available and countries such as the USA and Israel have now vaccinated >50% of adults…something about availability in Ethiopia/Africa continent”]. However, there [delete “are” and add “continue to be” scientifically accepted and recommended prevention measures against COVID-19 infection such as social distancing, frequent hand washing, use of face mask, and proper use of alcohol-based hand rubs or sanitizers (6-8).

With neither treatment nor vaccines [consider adding “readily available”], and [consider deleting “without preexisting immunity” because no one had preexisting immunity to this disease].

For “the effect might be devastating” perhaps you mean, “the virus continues to threaten the country” because of the multiple health challenges the continent [do you mean the country?...if you mean continent you need to specifically state Africa]…[at the end of this paragraph you could add something about the recent spike in India as a reminder of the continued risk of this pandemic even when some parts of the world are returning to pre COVID levels of engagement]

To contain the pandemic, the country established a National Ministerial Committee and the government declared [should be a state of emergency and not the state of emergency] on April 8, 2020. [For the following sentence consider this rewording and numbering the elements…On March 16, 2020 the committee released guidelines that included: 1) 14 days quarantine of passengers (travelers?) in isolated centers; 2) Ethiopian Airlines to stop flying to 30 countries;… 9) temporarily ceasing (do you mean closing? ceasing means taking away from the owners) night clubs and bars; regulating market to avoid unethical exploitation of the situation

In this study, healthcare workers and key informants in the community including local leaders [were not instead of will be] interviewed

The following sentence is unclear/can you update what you are trying to say here-This is helpful from the view of the following perspectives. Healthcare workers the frontline in battling the spread infection as a whole (12) . Secondly, community leaders are also the right of the country in prevention the COVID-19 infection (13).

[Can remove the following sentence because it repeats points noted in the prior section, if desired to keep could say something like.. “The basic protective measures against COVID-19 including distancing, personal protective equipment, and handwashing as noted above are poorly practiced in the community of …] Along with the above scientific explanations, controlling the spread of infection is essential to preventing outbreaks of COVID-19 (14).

Consider this rewording-Basic protective measures against the new coronavirus including stay at home, frequently washing hands with soap and water using alcohol-based hand rub or wash…Thus, the implementation of these practices to reduce the spread of COVID-19 would be challenging in Ethiopia…

RECOMMENDED [RECOMMENDED has not been previously defined or presented this way] prevention measures among community key informants and other community member’s [delete “perspective”] in South Gondar Zone, North west [Northwest?] Ethiopia.

Methods

Study area and period

Can you define Woredas?

This study was conducted on purposely selecting [do you mean selected?, but “purposely selecting could be removed either way”]

Currently, the zone is hardly working…[this statement is too subjective, can it be made more objective by stating how many beds the isolation center/ quarantine center/treatment center is able to accommodate. Similarly, later in the paragraph the 150 cases doesn’t seem like much, but could have more weight if clear that the area would not be able to handle a surge of cases].

Participants of the study and sampling procedures

…from the community [delete “were”] participated [in instead of for] Focus Group Discussions.

Data collection tools and procedures

[Can remove this sentence as it is stated above]-The interview process was continued until the data reach saturation, which defined as the point when answers no longer provide new or additional information on the research question and when recurrent patterns became apparent in the participants descriptions.

Some additional “were/was” before “participated/enhanced” that need to be removed

Results

Table 1-Need to keep the use of capital letters consistent

For quotes can you specifically state which IDI participant provided the quote, so which career were they coming from

The non-quoted paragraphs of “Sociodemographic and economic related barriers” section were confusing, please reword.

“Cultural religious related barriers”

What does this mean? “…did not affect those who had a strong religious practice”

As the participants said, almost all participants [delete “were”] trusted on the use of traditional treatments [delete “which will be”] prepared from different herbal plants. [Delete “As the” participants described, the disease [as the instead of “is like”] common cold and [believed it could] be healed by common traditional treatment modalities of the common cold. When [delete “they were”, “also”, “they said as they will use these traditional treatments prepared by the local traditional healers from different plant leaves and roots and to use holy water.” [the last part is redundant]

Reviewer #2: thanks to authors, all of my comments have been addressed. the manuscript can e accepted in current version.

**********

7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

If you choose “no”, your identity will remain anonymous but your review may still be made public.

Do you want your identity to be public for this peer review? For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: Yes: Assoc. Prof. Dr. Mohammad Amin Bahrami

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2021 Sep 24;16(9):e0257897. doi: 10.1371/journal.pone.0257897.r004

Author response to Decision Letter 1


12 Jun 2021

June 8, 2021

Dear, Editor,

Greetings!

Thank you very much for all the comments provided regarding our manuscript entitled “Community Risk perception and Barriers for the Practice of COVID-19 Prevention Measures in Northwest Ethiopia: A Qualitative Study” which are fully accepted and included in the revised version. I have accordingly made necessary revisions on the paper following the comments and suggestions provided from the reviewer 1. For your kind consideration, please find a point by point response to the comments in the next page of this letter and a submitted new revised version of the manuscript.

All new changes have been highlighted in dark blue in the main document in order to facilitate review.

I hope that you will find the edits as per your expectation and I look forwards to hear from you

soon.

Yours Sincerely,

Aragaw Tesfaw (MPH, Epidemiology)

Lecturer, Department of Public health

College of health sciences, Debre Tabor University

Email: aragetesfa05@gmail.com

Phone: +251921743820

Point by point responses to editor comments

Journal Requirements:

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Author Reponses: We revised and checked the references accordingly based on the comment

Review Comments to the Author

Reviewer #1: Thanks for taking the time to update the language and methods that now much more clearly explain the qualitative approach. A number of additional grammatical suggestions are provided below for the abstract, introduction, and methods as well as additional questions/comments. The results section and discussion can still use updating to the language to clarify meaning. I make a few suggestions below for the results section specifically. At the moment the discussion mostly serves to re-summarize the results rather than place the findings in context of the ongoing pandemic. For example, can you more specifically state how these findings relate to other studies in Ethiopia, Africa, or other lower income countries? Coming from a public health group could you state a little more about how these findings could be used? Have other areas in the country/continent done a better job in implementing educational campaigns? Can you draw from other campaigns that have done a good job in communicating information to rural areas that may serve COVID-19? Could these findings drive approaches to the vaccine campaign once supplies become available? For example, how might religious beliefs impact the community from taking the vaccine?

Author Reponses: we would like to say thank you for the constructive comments forwarded from the authors which are fully acceptable and revised accordingly based on the suggestions and comments. We tried to edit the grammatical errors and language in each section of the document and we now made necessary revisions. We tried to improve also the discussion section by comparing other studies conducted in Africa and Ethiopia as suggested by the reviewer. We tried to mentioned areas in Ethiopia and Africa which done a better job in implementing educational campaigns regarding the prevention of COVID-19. Regarding the findings of our study, we also mentioned in the discussion section about its how our findings will be used. We tried to mention also other campaigns that have done a good job in communicating information to rural areas that may serve COVID-19. As the reviewer mentioned, our study findings can drive approaches to the vaccine campaign once supplies become available. As we mentioned in the main document, religious beliefs will have an impact the community from taking the vaccine, since we are currently facing the challenge even though there are limited vaccines in the country for high risk groups. Still people are reluctant to take the vaccine due to different perceptions. some studies on vaccine acceptance found that the willing ness to accept the vaccine in Ethiopia is low.

Specific comments

Abstract

Methods: Community key informants and health extension workers were selected purposely for in-depth interviews and focus group discussion to [should this be “on” instead of “to”] maintaining WHO recommendations for social distancing and use of appropriate personal protective equipment [delete the 's.]

Author Reponses: corrected based on the comments

Specifically state the sample size number in the abstract.

Author Reponses: edited/corrected based on the comments

FGD has not been defined in the abstract, this acronym is also not needed and could just state focus group discussions throughout the paper.

Author Reponses: edited/ corrected based on the comments

Results: Three main themes and five categories were emerged from… and 2 religious leaders were participated...[delete was] conducted among purposely selected community members. The age of the participants [delete was] ranged from 24 to 70 years…

Author Reponses: edited/corrected based on the comments

For the last two sentences I would rearrange them so that it states- The major identified barriers for practicing COVID-19 prevention measures were the presence of strong cultural and religious practices, perceiving that the disease does not affect the young, misinformation about the disease, and “the” lack of trust on the prevention measures.

Author Reponses: edited/corrected based on the comments

Conclusions: Socio-cultural, religious, and economics related barriers were identified from the participant’s narratives for the practice of COVID-19 prevention measures in south Gondar Zone. Our findings suggest the need to strengthen [delete “ing”] community

Background

The world is closely watching the outbreak of “the” respiratory illness…

The world is now suffering from this global pandemic which [has killed instead of “ kills”] millions

Author Reponses: edited/corrected based on the comments

I would suggest the following change for this thought given the widespread availability of vaccines in parts of the world-There are not any proven pharmacological treatments [delete “and vaccines” … “until now”] although a number of trials are [consider adding “currently underway by scientist across” and delete “tested worldwide by several scientists in”] the globe. [Consider adding… “While several effective vaccinations are now available and countries such as the USA and Israel have now vaccinated >50% of adults…something about availability in Ethiopia/Africa continent”]. However, there [delete “are” and add “continue to be” scientifically accepted and recommended prevention measures against COVID-19 infection such as social distancing, frequent hand washing, use of face mask, and proper use of alcohol-based hand rubs or sanitizers (6-8).

Author Reponses: edited/corrected based on the comments

With neither treatment nor vaccines [consider adding “readily available”], and [consider deleting “without preexisting immunity” because no one had preexisting immunity to this disease].

Author Reponses: edited/corrected based on the comments

For “the effect might be devastating” perhaps you mean, “the virus continues to threaten the country” because of the multiple health challenges the continent [do you mean the country?...if you mean continent you need to specifically state Africa]…[at the end of this paragraph you could add something about the recent spike in India as a reminder of the continued risk of this pandemic even when some parts of the world are returning to pre COVID levels of engagement]

To contain the pandemic, the country established a National Ministerial Committee and the government declared [should be a state of emergency and not the state of emergency] on April 8, 2020. [For the following sentence consider this rewording and numbering the elements…On March 16, 2020 the committee released guidelines that included: 1) 14 days quarantine of passengers (travelers?) in isolated centers; 2) Ethiopian Airlines to stop flying to 30 countries;… 9) temporarily ceasing (do you mean closing? ceasing means taking away from the owners) night clubs and bars; regulating market to avoid unethical exploitation of the situation

In this study, healthcare workers and key informants in the community including local leaders [were not instead of will be] interviewed

The following sentence is unclear/can you update what you are trying to say here-This is helpful from the view of the following perspectives. Healthcare workers the frontline in battling the spread infection as a whole (12) . Secondly, community leaders are also the right of the country in prevention the COVID-19 infection (13).

Author Reponses: edited/corrected based on the comment in the main document

[Can remove the following sentence because it repeats points noted in the prior section, if desired to keep could say something like.. “The basic protective measures against COVID-19 including distancing, personal protective equipment, and handwashing as noted above are poorly practiced in the community of …] Along with the above scientific explanations, controlling the spread of infection is essential to preventing outbreaks of COVID-19 (14).

Author Reponses: edited/corrected

Consider this rewording-Basic protective measures against the new coronavirus including stay at home, frequently washing hands with soap and water using alcohol-based hand rub or wash…Thus, the implementation of these practices to reduce the spread of COVID-19 would be challenging in Ethiopia…

RECOMMENDED [RECOMMENDED has not been previously defined or presented this way] prevention measures among community key informants and other community member’s [delete “perspective”] in South Gondar Zone, North west [Northwest?] Ethiopia.

Author Reponses: edited/corrected in the main document

Methods

Study area and period

Can you define Woredas?

Author Reponses: Woredas are the lower administrative areas next to zone called also districts according to the Ethiopian government structure. A number of woreda’s form a zone in combination. Kebele →Woreda→ Zone → Region →Federal

This study was conducted on purposely selecting [do you mean selected?, but “purposely selecting could be removed either way”]

Author Reponses: edited/corrected based on the comment

Currently, the zone is hardly working…[this statement is too subjective, can it be made more objective by stating how many beds the isolation center/ quarantine center/treatment center is able to accommodate. Similarly, later in the paragraph the 150 cases doesn’t seem like much, but could have more weight if clear that the area would not be able to handle a surge of cases].

Author Reponses: edited/corrected based on the comment

Participants of the study and sampling procedures

…from the community [delete “were”] participated [in instead of for] Focus Group Discussions.

Author Reponses: edited/corrected based on the comment

Data collection tools and procedures

[Can remove this sentence as it is stated above]-The interview process was continued until the data reach saturation, which defined as the point when answers no longer provide new or additional information on the research question and when recurrent patterns became apparent in the participants descriptions.

Some additional “were/was” before “participated/enhanced” that need to be removed

Author Reponses: edited/corrected based on the comment

Results

Table 1-Need to keep the use of capital letters consistent

For quotes can you specifically state which IDI participant provided the quote, so which career were they coming from

Author Reponses: edited/corrected based on the comment

The non-quoted paragraphs of “Sociodemographic and economic related barriers” section were confusing, please reword.

Author Reponses: edited/corrected based on the comment

“Cultural religious related barriers”

What does this mean? “…did not affect those who had a strong religious practice”

Author Reponses: Cultural and religious barriers were the major perceived barriers mentioned from the participants of the study since there are strong religious and cultural practice in the area. Most people trusts religious rules than the modern health care practice. their trusts on the prevention methods is low.

As the participants said, almost all participants [delete “were”] trusted on the use of traditional treatments [delete “which will be”] prepared from different herbal plants. [Delete “As the” participants described, the disease [as the instead of “is like”] common cold and [believed it could] be healed by common traditional treatment modalities of the common cold. When [delete “they were”, “also”, “they said as they will use these traditional treatments prepared by the local traditional healers from different plant leaves and roots and to use holy water.” [the last part is redundant]

Author Reponses: we removed /corrected based on the comment

Reviewer #2: thanks to authors, all of my comments have been addressed. The manuscript can accepted in current version.

Author response: thank you very much for reviewing and giving constructive comments

________________________________________

Attachment

Submitted filename: Response to Reviewers.docx

Decision Letter 2

Johnson Chun-Sing Cheung

17 Aug 2021

PONE-D-21-07870R2

Community Risk perception and Barriers for the Practice of COVID-19 Prevention Measures in Northwest Ethiopia :  A Qualitative Study

PLOS ONE

Dear Dr. Tesfaw,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Oct 01 2021 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the academic editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

If you would like to make changes to your financial disclosure, please include your updated statement in your cover letter. Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

If applicable, we recommend that you deposit your laboratory protocols in protocols.io to enhance the reproducibility of your results. Protocols.io assigns your protocol its own identifier (DOI) so that it can be cited independently in the future. For instructions see: http://journals.plos.org/plosone/s/submission-guidelines#loc-laboratory-protocols. Additionally, PLOS ONE offers an option for publishing peer-reviewed Lab Protocol articles, which describe protocols hosted on protocols.io. Read more information on sharing protocols at https://plos.org/protocols?utm_medium=editorial-email&utm_source=authorletters&utm_campaign=protocols.

We look forward to receiving your revised manuscript.

Kind regards,

Johnson Chun-Sing Cheung, D.S.W.

Academic Editor

PLOS ONE

Journal Requirements:

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments (if provided):

As there are still a few minor points raised by the reviewer, please address to them carefully and submit your revision to us before we can proceed to publication. In order to speed up the process, only a brief rebuttal letter is required.

Review Comments to the Author:

Reviewer #1: Thank you once more for taking the time to address my prior comments. A number of grammatical errors remain especially in the discussion which makes the paper at times hard to read. Reading items aloud can sometimes help with these issues. Some suggestions below:

In the abstract, methods: “A total of 23 people were participated in the study” were should be removed.

Similarly in the results of the abstract: Were should be removed in the following sentences… “Three main themes and five categories were emerged”… “and 2 religious leaders were participated”…

Abstract, results: … “(7 participants in each round) was”… was should be were

Abstract, conclusions: … removed the “s” from economics

Background: Update the following sentence “There are no any proven pharmacological treatments developed for the disease until now, although a number of trials are currently underway by scientists across the globe. However, COVID-19 vaccines are developed within the shortest period in the history of vaccine production and now become now available and countries such as” to…There are no pharmacological treatments developed for the disease, although a number of trials are currently underway by scientists across the globe. However, COVID-19 vaccines are now available and countries such as…” (The other text is not needed and can be misleading without additional context about the time of vaccine development).

Background: Please update the following sentence… “…preCOvid levels of engagement, the risk of the pandemic is continued and becomes a global challenge (12). According to the June 8, 2021 Worldometer report, currently India and South Africa…” to …pre-COVID levels of engagement, the risk of the pandemic has continued and is a global challenge (12). According to the June 8, 2021 Worldometer report, India and South Africa…

Background: When listing out the guidelines make sure you are using a “;” after the guideline and not a “:” as you are before 3) and 4). Similarly, you are missing some numbers. There should be a “8” before medical professional training, which will require you to renumber afterwards. And “support the regions preparedness…” will be number 12. Consider the following rewording for the rest of that section. In this study, healthcare workers and key informants in the community including local leaders were interviewed either individually or as part of focus groups to share their perceived barriers to COVID-19 prevention measures. This is helpful from the view of the following perspectives. Healthcare workers are the frontline in battling the spread of infection as a whole (16)…[for the last sentence what does “right of the country” mean? Consider alternative wording for clarity].

In the next paragraph be sure to capitalize “South Gondar Zone” for consistency

Methods: For the data analysis procedure section, did you name the open code software?

Methods, ethical approval and consent to participant: Update… “This is because the study is just a qualitative research which did not have any intervention /clinical trial and did not have follow-ups. In addition, some of the participants were illiterate…” to This level of consent was sufficient because the study was not an intervention/clinical trial and did not have follow-ups. In addition, some of the participants were illiterate…

Results: In addition to some grammar errors and reworking of some sentences that could be shortened for clarity, some work could be done to better organize the quotes. For example, temperature was noted both under Socio-demographic and economic related barriers and Cultural and religious related barriers

Discussion: Consider the following updates… As evidence shows, the recommended prevention methods of COVID-19 are effective measures to control the spread of the pandemic (10, 14, 23). However, the practice of such prevention measures is not consistent regionally as documented in Ethiopia despite efforts are made by the government (11, 15, 24). Therefore, we examined the perceived barriers for the practice of prevention measures and community risk perception of COIVID-19 focusing on both rural and urban settings.

Discussion: For reference 25 you note “less than half percent: which would mean 0.5%...I believe you mean to say less than 50 percent. As the abstract notes “The overall rate of information exposure about COVID-19 was 44.9%.”

Discussion: Consider the following rewrite for paragraph 2- The other important recommended and effective prevention measure is stay at home; however, our findings showed that it is a very difficult preventive measure to practice since most people live a hand--to--mouth way of life. Therefore, they need to get their daily consumption through daily work otherwise many will face hunger. As a result, most people cannot stay at home. Further, because Ethiopia is one of the lowest-income countries in the world and has a very young population, many people live together in a clustered environment, approximately 4-8 people in a single household [note, I don’t think it uncommon for 4 people to live in a single household so maybe you mean to additional note in a single room? Or note the size of the household]. This living situation provides a ripe environment for a contagious diseases like COVID-19. [There is also a sentence about negligence in your text but I’m not sure how the negligence part fits with the above text].

Again, there are several other sections within the discussion that could be updated for clarity such the increased interactions because of religious and cultural practices. The latter is an important point, again one could think back to India’s surge in relation to their religious celebrations or the number of mass outbreaks in the United States as a result of church attendance and singing without masks, but the sentences need to be rewritten to make the point more salient.

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLoS One. 2021 Sep 24;16(9):e0257897. doi: 10.1371/journal.pone.0257897.r006

Author response to Decision Letter 2


7 Sep 2021

September 06, 2021

Dear, Editor,

Greetings!

Thank you very much for all the comments provided regarding our manuscript entitled “Community Risk perception and Barriers for the Practice of COVID-19 Prevention Measures in Northwest Ethiopia: A Qualitative Study” which are fully accepted and included in the revised version. I have accordingly made necessary revisions on the paper following the comments and suggestions provided from the reviewer. For your kind consideration, please find a point by point response to the comments in the next page of this letter and a submitted new revised version of the manuscript.

All new changes have been highlighted in dark blue in the main document in order to facilitate review.

I hope that you will find the edits as per your expectation and I look forwards to hear from you

soon.

Yours Sincerely,

Aragaw Tesfaw (MPH/Epidemiology)

Assistant Professor, Department of Public health

College of health sciences, Debre Tabor University

Email: aragetesfa05@gmail.com

Phone: +251921743820

I. Point by point responses to reviewer comments

Reviewer #1: Thank you once more for taking the time to address my prior comments. A number of grammatical errors remain especially in the discussion which makes the paper at times hard to read. Reading items aloud can sometimes help with these issues. Some suggestions below:

In the abstract, methods: “A total of 23 people were participated in the study” were should be removed.

Author response: thank you very much for reviewing and giving constructive comments. We removed as commented by the reviewer

Similarly in the results of the abstract: Were should be removed in the following sentences… “Three main themes and five categories were emerged”… “and 2 religious leaders were participated”…

Abstract, results: … “(7 participants in each round) was”… was should be were

abstract, conclusions: … removed the “s” from economics

Author response: corrected based on the comment in the main document

Background: Update the following sentence “There are no any proven pharmacological treatments developed for the disease until now, although a number of trials are currently underway by scientists across the globe. However, COVID-19 vaccines are developed within the shortest period in the history of vaccine production and now become now available and countries such as” to…There are no pharmacological treatments developed for the disease, although a number of trials are currently underway by scientists across the globe. However, COVID-19 vaccines are now available and countries such as…” (The other text is not needed and can be misleading without additional context about the time of vaccine development).

Author response: corrected based on the comment

Background: Please update the following sentence… “…pre-COvid levels of engagement, the risk of the pandemic is continued and becomes a global challenge (12). According to the June 8, 2021 Worldometer report, currently India and South Africa…” to …pre-COVID levels of engagement, the risk of the pandemic has continued and is a global challenge (12). According to the June 8, 2021 Worldometer report, India and South Africa…

Author response: Updated based on the comment in the main document

Background: When listing out the guidelines make sure you are using a “;” after the guideline and not a “:” as you are before 3) and 4). Similarly, you are missing some numbers. There should be a “8” before medical professional training, which will require you to renumber afterwards. And “support the regions preparedness…” will be number 12. Consider the following rewording for the rest of that section. In this study, healthcare workers and key informants in the community including local leaders were interviewed either individually or as part of focus groups to share their perceived barriers to COVID-19 prevention measures. This is helpful from the view of the following perspectives. Healthcare workers are the frontline in battling the spread of infection as a whole (16)… [for the last sentence what does “right of the country” mean? Consider alternative wording for clarity].

Author response: corrected based on the comment in the main document

In the next paragraph be sure to capitalize “South Gondar Zone” for consistency

Author response: corrected/edited based on the comment

Methods: For the data analysis procedure section, did you name the open code software?

Author response: open code software version 4.02 /corrected based on the comment in the main document

Methods, ethical approval and consent to participant: Update… “This is because the study is just a qualitative research which did not have any intervention /clinical trial and did not have follow-ups. In addition, some of the participants were illiterate…” to This level of consent was sufficient because the study was not an intervention/clinical trial and did not have follow-ups. In addition, some of the participants were illiterate…

Results: In addition to some grammar errors and reworking of some sentences that could be shortened for clarity, some work could be done to better organize the quotes. For example, temperature was noted both under Socio-demographic and economic related barriers and Cultural and religious related barriers.

Author response: corrected based on the comment in the main document

Discussion: Consider the following updates… As evidence shows, the recommended prevention methods of COVID-19 are effective measures to control the spread of the pandemic (10, 14, 23). However, the practice of such prevention measures is not consistent regionally as documented in Ethiopia despite efforts are made by the government (11, 15, 24). Therefore, we examined the perceived barriers for the practice of prevention measures and community risk perception of COIVID-19 focusing on both rural and urban settings.

Author response: corrected based on the comment in the main document

Discussion: For reference 25 you note “less than half percent: which would mean 0.5%...I believe you mean to say less than 50 percent. As the abstract notes “The overall rate of information exposure about COVID-19 was 44.9%.”

Author response: thank you! we corrected based on the comment in the main document

Discussion: Consider the following rewrite for paragraph 2- The other important recommended and effective prevention measure is stay at home; however, our findings showed that it is a very difficult preventive measure to practice since most people live a hand--to--mouth way of life. Therefore, they need to get their daily consumption through daily work otherwise many will face hunger. As a result, most people cannot stay at home. Further, because Ethiopia is one of the lowest-income countries in the world and has a very young population, many people live together in a clustered environment, approximately 4-8 people in a single household [note, I don’t think it uncommon for 4 people to live in a single household so maybe you mean to additional note in a single room? Or note the size of the household]. This living situation provides a ripe environment for a contagious diseases like COVID-19. [There is also a sentence about negligence in your text but I’m not sure how the negligence part fits with the above text].

Again, there are several other sections within the discussion that could be updated for clarity such the increased interactions because of religious and cultural practices. The latter is an important point, again one could think back to India’s surge in relation to their religious celebrations or the number of mass outbreaks in the United States as a result of church attendance and singing without masks, but the sentences need to be rewritten to make the point more salient.

Author response: thank you very much for reviewing and giving constructive comments, we tried to modified the document based on the comments

________________________________________

Attachment

Submitted filename: Response to Reviewers.docx

Decision Letter 3

Johnson Chun-Sing Cheung

14 Sep 2021

Community Risk perception and Barriers for the Practice of COVID-19 Prevention Measures in Northwest Ethiopia :  A Qualitative Study

PONE-D-21-07870R3

Dear Dr. Tesfaw,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

Within one week, you’ll receive an e-mail detailing the required amendments. When these have been addressed, you’ll receive a formal acceptance letter and your manuscript will be scheduled for publication.

An invoice for payment will follow shortly after the formal acceptance. To ensure an efficient process, please log into Editorial Manager at http://www.editorialmanager.com/pone/, click the 'Update My Information' link at the top of the page, and double check that your user information is up-to-date. If you have any billing related questions, please contact our Author Billing department directly at authorbilling@plos.org.

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they’ll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact onepress@plos.org.

Kind regards,

Johnson Chun-Sing Cheung, D.S.W.

Academic Editor

PLOS ONE

Acceptance letter

Johnson Chun-Sing Cheung

17 Sep 2021

PONE-D-21-07870R3

Community Risk perception and Barriers for the Practice of COVID-19 Prevention Measures in Northwest Ethiopia:  A Qualitative Study

Dear Dr. Tesfaw:

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now with our production department.

If your institution or institutions have a press office, please let them know about your upcoming paper now to help maximize its impact. If they'll be preparing press materials, please inform our press team within the next 48 hours. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information please contact onepress@plos.org.

If we can help with anything else, please email us at plosone@plos.org.

Thank you for submitting your work to PLOS ONE and supporting open access.

Kind regards,

PLOS ONE Editorial Office Staff

on behalf of

Dr. Johnson Chun-Sing Cheung

Academic Editor

PLOS ONE

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 File. Study information sheet for participants of in-depth interview and focus group discussion.

    (PDF)

    S2 File. In-depth interview guide.

    (PDF)

    S3 File. Focus group discussion guide.

    (PDF)

    S4 File. Themes and categories (subthemes) developed from the narration of in-depth interviews and focus group discussion.

    (PDF)

    Attachment

    Submitted filename: Response to Reviewers.docx

    Attachment

    Submitted filename: Response to Reviewers.docx

    Attachment

    Submitted filename: Response to Reviewers.docx

    Data Availability Statement

    All relevant data are within the paper and its Supporting Information files.


    Articles from PLoS ONE are provided here courtesy of PLOS

    RESOURCES