Transgender and gender diverse individuals experience pervasive invalidation and discrimination in our society. Gender-minority stressors, including gender-related stigma and discrimination, increase vulnerability to health problems (as compared with cisgender peers) resulting in disparities in virtually every domain of life, from higher rates of victimisation and mental health problems, including suicidality, to inadequate access to public accommodations, housing, and necessary health care.1 Although the full effects of the COVID-19 pandemic will take years to elucidate, especially as we face waves of multiple SARS-CoV-2 variants (eg, delta [B.1.617.2]), it is apparent that the pandemic has resulted in exacerbated disparities for transgender and gender diverse people across several crucial determinants of health.2 Thankfully, necessity has bred ingenuity, including the widespread adoption of telehealth, a practice that can better meet the needs of transgender and gender diverse people beyond the scope of the current public health crisis. Building on previous correspondence,2 we review lessons learned from 2020 to see how health care for transgender and gender diverse individuals might be improved in the coming years.
For transgender and gender diverse individuals with intersecting marginalised identities (eg, transgender women of colour), structural or systemic inequity and discrimination became particularly pronounced during the COVID-19 pandemic: higher proportions of individuals in unstable housing and employment, and greater financial difficulties were reported.3 In a US poll of 7000 lesbian, gay, bisexual, transgender, and queer adults from April to May, 2020, the Human Rights Campaign found 19% of transgender and gender diverse people and 26% of minority ethnic transgender and gender diverse people of colour became unemployed due to the pandemic, compared with 12% of the general population.4 Economic hardship disproportionately affected minority ethnic transgender and gender diverse people, with 59% of transgender and gender diverse people and 67% of minority ethnic transgender and gender diverse people stating they were very concerned they could not pay their bills, compared with 15% of the general population. Recent policy efforts, such as the Fair Housing Act in the USA, are intended to reduce housing discrimination related to transgender and gender diverse individuals, yet the impact remains to be seen.
Although the COVID-19 pandemic compounded many existing disparities, the most notable was markedly reduced access to expert clinical care. As public health authorities called for appropriate measures to mitigate the spread of COVID-19, delays occurred in accessing gender-affirming health services. For example, the cessation of non-emergent surgeries in the USA and many other countries effectively closed the door on all gender-affirming procedures and further delayed access to medically necessary procedures for transgender and gender diverse people.5 Additionally, access to even the most basic health services became difficult. Finding a new health-care clinician for evaluation for gender-affirming hormone therapy became more challenging as health-care systems had limited enrolment and prioritised patients already established in their system. While the pandemic severely curtailed access for existing patients within health systems, it left many new patients without recourse.
As health-care systems adapted to the new realities of care and integrated telemedicine, transgender and gender diverse people newly seeking gender-affirming health care were faced with a patchwork of practice approaches. Given limited guidance across practice settings, health professionals adept at gender-affirming care either adapted their approach to hormone initiation, forgoing in-person physical examinations, or were adamant that a physical examination was essential before prescribing. Without clear guidance from transgender health societies and organisations, clinicians were not able to provide congruent policies and messaging across clinics, leaving new patients to search for clinicians who felt most comfortable initiating gender-affirming medical interventions while foregoing in-person assessment.
Mental health disparities experienced by transgender and gender diverse people were notably exacerbated during the pandemic, as COVID-19 precautions reduced access to social support.6 For transgender and gender diverse people, this reduced access meant losing a crucial source of resilience against the effects of gender-minority stress. A Washington Post review of calls to Trans Lifeline—a crisis telephone line staffed by transgender and gender diverse people—indicated that 24% of calls from March to July, 2020, specifically mentioned the absence of a transgender community during this time.7 Relatedly, transgender and gender diverse people had fewer opportunities to spend time socially acknowledged in their affirmed gender during the COVID-19 pandemic when in-person gatherings were forbidden. In response to reduced access to care and decreased social connectedness, mental health indicators among transgender and gender diverse people worsened, with increased rates of depression, anxiety, and suicidality.6
Coping with the treatment of and recovery from COVID-19 itself might be challenging for transgender and gender diverse individuals given decreased in-person support during this time and worsened mental health indicators. In addition to persistent physical symptoms (breathlessness, early fatigue, etc), COVID-19 often also involves a psychological toll including mental health impairments (cognitive impairment, post-traumatic stress disorder, and anxiety), which might compound existing stressors.8 Furthermore, after diagnosis with COVID-19, one must often undergo an isolation process at home or in a hospital room while contemplating questions about recovery and coping with the impact of limited in-person social support.
As the USA continues to recognise the destabilising effects of the COVID-19 pandemic, the health-care system is challenged to learn from these temporary fixes to best address longstanding as well as pandemic-related barriers to delivery and access of equitable health care for transgender and gender diverse people. As such, while ongoing efforts need to be focused on reducing structural, systemic, and interpersonal gender-minority stress, racism, and other forms of oppression, continuing insurance coverage of telemedicine and improving necessary infrastructure (eg, high-speed internet) would allow people in rural areas, older people, and people with restricted mobility and transport to have access to quality health care.9 Additionally, updating cross-state licensing regulations to allow expanded forms of interstate practice would demonstrate clear benefits in improving access to gender-affirming health care. There are already free-market solutions using existing efforts to reduce barriers to interstate licensing regulations and telemedicine: private health technology companies such as Plume and Solace have gained momentum as a mechanism of obtaining health information and gender-affirming hormone therapy virtually.
The COVID-19 pandemic continues to stress health-care systems and underscores systematic deficiencies that transgender and gender diverse individuals face in seeking care. With the rapid proliferation of telemedicine in this time of need as well as innovative virtual resources, patients and clinicians have experienced a system that can more equitably serve patients where they live. Rather than return to that status quo of patchwork systems with numerous coverage and access barriers to gender-affirming care, there is an opportunity to create a novel, improved standard to ensure everyone, especially transgender and gender diverse people, can benefit from increased access to quality and compassionate health care, inclusive of primary, mental, and specialty care.

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AWB declares the National Institute on Drug Abuse/National Institutes of Health (K23DA043418-04) supported her salary. CGS declares that the National Heart, Lung, and Blood Institute/National Institutes of Health (1K01HL151902-01A1), American Heart Association (20CDA35320148), and Boston University School of Medicine Department of Medicine Career Investment Award supported his salary. CGS is an unpaid board member of the US Professional Association for Transgender Health. CMB, MI, and CAS declare no competing interests. The views reflected herein are those of the individual authors and are not those of the respective institutional affiliations of the authors or the US Government.
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