Table 5.
Key Knowledge Gaps |
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1. Optimal monitoring frequency and duration to measure AF burden |
2. Threshold of AF burden that results in an increased risk of stroke, heart failure, dementia, and other AF-related outcomes |
3. Prevalence of subclinical AF and effects of AF burden in broad community-based cohorts |
4. Risk factors and determinants of AF burden in broad community-based cohorts |
5. Lack of temporal relationship between AF burden and stroke in AF patients |
6. How AF burden will need to be redefined in the era of widespread, long-term continuous cardiac monitoring |
7. Threshold of AF burden that indicates need for anticoagulation in patients with higher risk of stroke (eg, CHA2DS2-VASc score ≥2) |
AF indicates atrial fibrillation.