Table 3.
Characteristics of primary Sjögren’s syndrome patients based on adropin level.
| Parameter | Lower Adropin (<3.73 ng/mL) (N = 26) |
Higher Adropin (>3.73 ng/mL) (N = 26) |
p * |
|---|---|---|---|
| Age (years) | 51.0 ± 9.83 | 57.6 ± 12.3 | 0.284 |
| Body mass index (kg/m2) | 24.8 ± 4.1 | 24.83 ± 2.5 | 0.978 |
| SBP (mmHg) | 123.6 ± 18.46 | 128.8 ± 14.9 | 0.270 |
| DBP (mmHg) | 79.6 ± 8.8 | 80.8 ± 5.9 | 0.086 |
| Total cholesterol (mmoL/L) | 5.56 ± 1.08 | 5.76 ± 1.21 | 0.535 |
| HDL (mmoL/L) | 1.46 ± 0.36 | 1.56 ± 0.38 | 0.362 |
| LDL (mmoL/L) | 3.35 ± 0.89 | 3.76 ± 0.99 | 0.119 |
| TG (μmol/L) | 1.15 ± 0.43 | 1.20 ± 0.40 | 0.694 |
| hsCRP (mg/L) | 1.35 (0.9–2.7) | 1.15 (0.80–5.6) | 0.869 |
| Anti SSB/La (AU/mL) | 36.0 (7.0–79.0) | 9.5 (2.0–88.0) | 0.734 |
| AntiSSA/Ro52 (AU/mL) | 73.0 (12.0–125.0) | 109.0 (17.0–172.0) | 0.272 |
| Anti SSA/Ro60 (AU/mL) | 101.0 (60.0–116.0) | 107.5 (52.0–118.0) | 0.963 |
| Disease duration (years) † | 6 (4.0–12.0) | 6 (3.0–10.0) | 0.607 |
| ESSDAI | 2.0 (1.0–3.0) | 2.5 (1.0–3.0) | 0.641 |
| SSDDI | 3.0 (2.0–4.0) | 2.0 (1.0–2.0) | <0.001 |
| FRS (%) | 4.25 (1.2–6.2) | 2.3 (1.4–5.2) | 0.374 |
Abbreviations: SBP: systolic blood pressure; DBP: diastolic blood pressure; HDL: high density lipoprotein; LDL: low density lipoprotein; TG: Triglycerides; hsCRP: high sensitivity C-reactive protein; ESSDAI: EULAR Primary Sjögren’s Syndrome Disease Activity Index; SSDDI: Sjögren’s Syndrome Disease Damage Index; FRS: Framingham Risk Score for Coronary Heart Disease; Data are presented as whole number (percentage), mean ± standard deviation or median (IQR), * t-test for independent samples or Mann-Whitney U test, † time period from the initial diagnosis.