Table 1.
Baseline characteristics of the total population and according to presence of CAD.
| All (n = 287) | No CAD (n = 69) | Non-Significant CAD (n = 88) | Significant CAD (n = 130) | p-Value 1 | p-Value 2 | p-Value 3 | |
|---|---|---|---|---|---|---|---|
| Age (years) * | 62.4 (40.1–87.2) | 60.8 (43.8–80.6) | 61.7 (40.1–79.6) | 63.7 (40.9–87.2) | 0.079 | 0.085 | 0.037 |
| Sex; female, n (%) | 102 (35.5) | 44 (63.8) | 32 (36.4) | 26 (20.0) | <0.001 | <0.001 | <0.001 |
| BMI (kg/m2) | 26.6 (24.7, 29.6) | 26.8 (24.3, 30.4) | 26.3 (24.7, 29.0) | 26.6 (25.0, 30.0) | 0.271 | 0.954 | 0.524 |
| Diabetes, n (%) | 56 (19.5) | 15 (21.7) | 12 (13.6) | 29 (22.3) | 0.248 | 0.593 | 0.927 |
| Hypertension, n (%) | 169 (58.9) | 34 (49.3) | 50 (56.8) | 85 (65.4) | 0.081 | 0.063 | 0.041 |
| Resting heart rate (bpm) | 68 (61, 77) | 70 (62, 75) | 70 (62, 80) | 67 (59, 75) | 0.076 | 0.630 | 0.189 |
| Hypercholesterolemia, n (%) | 231 (80.5) | 42 (60.9) | 71 (80.7) | 118 (90.8) | <0.001 | <0.001 | <0.001 |
| Smoker, n (%) 4 | 52 (18.1) | 39 (56.5) | 54 (61.4) | 83 (63.9) | 0.602 | 0.348 | 0.391 |
| HbA1c % | 5.7 (5.4, 6.2) | 5.7 (5.4, 6.2) | 5.6 (5.4, 5.9) | 5.7 (5.4, 6.3) | 0.232 | 0.720 | 0.753 |
| Creatinine (μmol/L) | 79 (69, 89) | 73.5 (66, 80.5) | 78 (68, 88) | 82 (73, 93) | <0.001 | <0.001 | <0.001 |
| Total cholesterol (mmol/L) | 4.6 (3.9, 5.6) | 5.3 (4.5, 6.2) | 4.7 (3.9, 5.8) | 4.3 (3.7, 5) | <0.001 | <0.001 | <0.001 |
| LDL (mmol/L) | 2.6 (2.1, 3.5) | 3.0 (2.4, 4.0) | 2.6 (2.0, 3.6) | 2.4 (2.0, 3.0) | 0.001 | 0.002 | <0.001 |
| Medication, n (%) | |||||||
| Platelet inhibitor 5 | 209 (72.8) | 29 (42.0) | 63 (71.6) | 117 (90.0) | <0.001 | <0.001 | <0.001 |
| ACEI/ARB | 103 (35.9) | 17 (24.6) | 35 (39.8) | 51 (39.2) | 0.083 | 0.026 | 0.054 |
| Betablocker | 119 (41.5) | 14 (20.3) | 34 (38.6) | 71 (54.6) | <0.001 | <0.001 | <0.001 |
| Calcium blocker | 47 (16.3) | 5 (7.3) | 14 (15.9) | 28 (21.5) | 0.035 | 0.019 | 0.013 |
| Statins | 203 (70.7) | 34 (49.3) | 60 (68.2) | 109 (83.9) | <0.001 | <0.001 | <0.001 |
Variables are given as medians (25th, 75th percentile) unless stated otherwise. * Mean (min, max). 1 refers to the difference between the groups of CAD. 2 Refers to differences between no CAD and any CAD (non-significant CAD and significant CAD together). 3 refers to differences between no CAD and significant CAD. 4 Includes smokers and previous smokers. 5 Refer to the use of acetylsalisylic acid, dipyramidol or clopidogrel, or combinations of these. BMI = body mass index, bpm = beats per minute, LDL = low-density lipoprotein, ACEI = angiotensin-converting-enzyme inhibitor, ARB = angiotensin II receptor blocker.