Figure 3.

Results of the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) cell viability assay on HSC-2 human oral cancer (grey), T24 human bladder cancer (blue), and A549 human lung cancer cells (green) with compounds 6-methylaminonicotinamide (6-MANA), parent compound GYZ-319, and prodrugs 12e and 14e. Compounds were incubated for 24, 48, and 72 h at 1, 10, and 100 µM concentrations. As no effects were observed at 1 and 10 µM, only results at 100 µM are depicted. Results are presented as mean values with standard deviation from three independent experiments performed in triplicate.