Table 2.
Antimicrobial susceptibility profiles of different bacterial hosts carrying blaCTX-M and blaTEM-positive plasmids, E. coli-J53 transconjugants and the E. coli-J53 recipient.
| Strains 1 | MICs (μg/mL) 2 | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| TET | TES | AMC | CEP | AZT | MPN | AMP | CTX | KAN | CIP | |
| 1557 | 128 | 8/160 | 128/64 | 16 | >64 | 0.15 | >256 | >256 | 1024 | 64 |
| T-1557 | 1 | 1/10 | 128/64 | 8 | 16 | 0.15 | >256 | >256 | 0.25 | 0.25 |
| 1584 | 512 | 8/320 | 128/64 | 16 | 32 | 0.15 | >256 | >256 | 64 | 128 |
| T-1584 | 1 | 1/10 | 128/64 | 8 | 8 | 0.15 | >256 | >256 | 0.25 | 0.25 |
| 1587 | 256 | 8/160 | 128/64 | 16 | >64 | 0.15 | >256 | >256 | 256 | 128 |
| T-1587 | 1 | 1/10 | 128/64 | 8 | 16 | 0.15 | >256 | >256 | 0.25 | 0.25 |
| 1591 | 256 | 8/320 | 64/32 | 16 | >64 | 0.15 | >256 | >256 | 256 | 64 |
| T-1591 | 1 | 1/10 | 64/32 | 8 | 16 | 0.15 | >256 | >256 | 0.25 | 0.25 |
| J53 | 1 | 1/10 | 1/0.5 | 0.25 | 1 | 0.03 | 2 | 0.25 | 0.25 | 0.25 |
1 T-1557, T-1584, T-1587 and T-1591 represent the transconjugations of E. coli 1557, E. coli 1584, E. coli 1587 and E. coli 1591. 2 MIC, minimum inhibitory concentration. Antimicrobial agents are abbreviated as follows: Tetracycline (TET), Trimethoprim-sulfamethoxazole (TES), Amoxicillin-clavulanate (AMC), Cefepime (CEP), Aztreonam (AZT), Meropenem (MPN), Ampicillin (AMP), Cefotaxime (CTX), Kanamycin (KAN), Ciprofloxacin (CIP). Data are summarised from three different experiments.