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Abbreviations.
| hERG liability | hERG: TOX_hERG > 6 |
| acute toxicity in rats | ra: TOX_RAT < 300 |
| carcinogenicity in chronic rat studies | Xr: Rat_TD50 < 4 |
| carcinogenicity in chronic mouse studies | Xm: Mouse_TD50 < 25 |
| hepatotoxicity | Hp: (TOX_AlkPhos = Toxic OR TOX_GGT = Toxic OR TOX_LDH = Toxic) AND (TOX_SGOT = Toxic OR TOX_SGPT = Toxic) |
| SGOT and SGPT elevation | SG: TOX_SGOT = Toxic AND TOX_SGPT = Toxic |
| Mu | TOX_MUT_Risk > 2 |
