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SynCav1 inhibits excessive mitochondria fission observed in 12 m PSAPP mice hippocampus. (A) Represent image from 9 m. (B) and 12 m (C). (D) Quantification of immunoblots at 12 m. Data are presented as mean ± S.E.M., n = 3 per group for 9 m, n = 6–10 animals per group for 12 m. Data were analyzed using one-way analysis of variance (ANOVA) followed by Fisher’s LSD multiple comparisons test. Significance was assumed when p < 0.05. * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.
