Table 2.
Gene Rank 2 | Mice | Humans | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Whole Brain | Cortex | Cerebellum | Striatum | Substantia Nigra | Blood | Peripheral Blood | ||||||||
HKG | Score 1 | HKG | Score | HKG | Score | HKG | Score | HKG | Score | HKG | Score | HKG | Score | |
1 | Psmd6 | 1.86 | Bcat2 | 1.32 | Aars | 1.78 | Sars | 1.50 | Hprt | 1.50 | Hprt | 1.78 | POLR2A | 1.41 |
2 | Aars | 2.00 | Polr2f | 2.06 | Polr2f | 1.86 | Psmd7 | 2.21 | Psmd7 | 2.00 | Polr2f | 1.86 | PSMD6 | 2.45 |
3 | Polr2f | 2.11 | Aars | 2.63 | Psmd6 | 2.45 | Aars | 3.25 | Bcat2 | 3.00 | Psmd6 | 2.45 | PSMA5 | 2.82 |
4 | Psmd7 | 3.08 | Psmd6 | 3.46 | Polr2a | 2.63 | Polr2a | 3.46 | Psmd6 | 3.83 | Psmd7 | 2.83 | PSMD7 | 3.98 |
5 | Sars | 4.16 | Polr2a | 5.00 | Bcat2 | 5.38 | Bcat2 | 4.60 | Aars | 4.43 | Sars | 4.61 | SARS | 4.23 |
6 | Bcat2 | 6.24 | Psmd7 | 5.09 | Psmd7 | 5.48 | Hprt | 4.61 | Polr2f | 5.12 | Bcat2 | 5.73 | HPRT1 | 4.30 |
7 | Polr2a | 7.24 | Sars | 7.24 | Sars | 6.96 | Psmd6 | 5.96 | Sars | 5.44 | Polr2a | 7.00 | AARS1 | 6.00 |
8 | Hprt | 7.44 | Hprt | 7.44 | Hprt | 7.74 | Polr2f | 7.20 | Polr2a | 8.00 | Aars | 8.00 |
1 Score—a comprehensive score calculated using the RefFinder program. 2 Gene rank (a place in the rating of stability of expression) is based on sorting HKGs by their comprehensive scores from minimum to maximum. The first place in the ranking (gene rank = 1) is assigned to the gene with the minimum comprehensive score, and this gene is considered the most stably expressed HKG in the tissue under study. The last place in the ranking (gene rank = 8) is assigned to the gene with the maximum comprehensive score, and this HKG is considered the least stably expressed HKG.