Skip to main content
. 2021 Aug 30;10(9):2252. doi: 10.3390/cells10092252

Table 2.

Table of the stability of expression of potential HKGs in the brain and peripheral blood of experimental group of mice and peripheral blood of experimental group of mice and PD patients according to the RefFinder program.

Gene Rank 2 Mice Humans
Whole Brain Cortex Cerebellum Striatum Substantia Nigra Blood Peripheral Blood
HKG Score 1 HKG Score HKG Score HKG Score HKG Score HKG Score HKG Score
1 Psmd6 1.86 Bcat2 1.32 Aars 1.78 Sars 1.50 Hprt 1.50 Hprt 1.78 POLR2A 1.41
2 Aars 2.00 Polr2f 2.06 Polr2f 1.86 Psmd7 2.21 Psmd7 2.00 Polr2f 1.86 PSMD6 2.45
3 Polr2f 2.11 Aars 2.63 Psmd6 2.45 Aars 3.25 Bcat2 3.00 Psmd6 2.45 PSMA5 2.82
4 Psmd7 3.08 Psmd6 3.46 Polr2a 2.63 Polr2a 3.46 Psmd6 3.83 Psmd7 2.83 PSMD7 3.98
5 Sars 4.16 Polr2a 5.00 Bcat2 5.38 Bcat2 4.60 Aars 4.43 Sars 4.61 SARS 4.23
6 Bcat2 6.24 Psmd7 5.09 Psmd7 5.48 Hprt 4.61 Polr2f 5.12 Bcat2 5.73 HPRT1 4.30
7 Polr2a 7.24 Sars 7.24 Sars 6.96 Psmd6 5.96 Sars 5.44 Polr2a 7.00 AARS1 6.00
8 Hprt 7.44 Hprt 7.44 Hprt 7.74 Polr2f 7.20 Polr2a 8.00 Aars 8.00

1 Score—a comprehensive score calculated using the RefFinder program. 2 Gene rank (a place in the rating of stability of expression) is based on sorting HKGs by their comprehensive scores from minimum to maximum. The first place in the ranking (gene rank = 1) is assigned to the gene with the minimum comprehensive score, and this gene is considered the most stably expressed HKG in the tissue under study. The last place in the ranking (gene rank = 8) is assigned to the gene with the maximum comprehensive score, and this HKG is considered the least stably expressed HKG.