Table 3.

Summary table of the stability of expression of potential HKGs based on total score in the brain and peripheral blood of mice and human peripheral blood according to the RefFinder program regardless of the presence or absence of pathology.

Gene Rank 2	Mice												Humans
	Whole Brain		Cortex		Cerebellum		Striatum		Substantia Nigra		Peripheral Blood		Peripheral Blood
	HKG	S-Score 1	HKG	S-Score	HKG	S-Score	HKG	S-Score	HKG	S-Score	HKG	S-Score	HKG	S-Score
1	Aars	4.21	Polr2f	4.27	Psmd6	5.08	Psmd7	3.21	Psmd7	3.32	Polr2f	4.24	PSMD6	4.56
2	Psmd7	4.65	Aars	4.31	Aars	5.09	Aars	5.46	Aars	6.11	Hprt	5.76	POLR2A	4.63
3	Psmd6	5.84	Bcat2	5.85	Polr2f	6.16	Sars	6.06	Bcat2	6.87	Sars	6.18	SARS1	5.80
4	Bcat2	9.23	Psmd7	7.15	Psmd7	7.34	Polr2a	6.77	Hprt	9.50	Psmd7	6.99	PSMA5	6.76
5	Polr2f	9.55	Psmd6	7.29	Polr2a	8.29	Hprt	7.92	Sars	10.05	Psmd6	7.37	HPRT1	7.46
6	Polr2a	9.69	Polr2a	11.44	Bcat2	10.17	Bcat2	10.52	Psmd6	10.07	Polr2a	9.71	PSMD7	8.54
7	Sars	11.40	Hprt	12.39	Hprt	10.87	Psmd6	12.44	Polr2a	10.83	Bcat2	10.87	AARS1	13.00
8	Hprt	13.68	Sars	15.24	Sars	12.69	Polr2f	15.20	Polr2f	11.21	Aars	16.00

¹ S-Score—the summarized comprehensive score for each HKG in each tissue was calculated as the sum of the scores from Table 1 and Table 2. ² Gene rank is based on sorting HKGs by their summarized comprehensive score from the minimum value, where the corresponding gene is assigned gene rank = 1, to the maximum value, where the corresponding gene is assigned gene rank = 8. The 1st place in the ranking (gene rank = 1) belongs to the most stable housekeeping gene.