Figure 6.

The activity of lysosomal glycohydrolases and expression levels of proteases in rFFFs (A) and rBM-MSCs (B) from ALS1 and WT rats. Levels of glycohydrolases were measured by using specific fluorogenic substrates (see Section 2.14 for details). Levels of proteases were determined by Western blotting (see also Figure S4B,C in Supplementary File). Shown are the densitometry analyses of all experiments. Results are expressed as the mean ± SD of three independent experiments, each in triplicates. ns, not significant, * p < 0.05, ** p < 0.01, *** p < 0.001, **** p < 0.0001.