Table 1.

IC₅₀ of 5-FU in CRC cell lines. The concentrations of Cur are 15 μM for HT-29 cell lines and 7.5 μM for SW480 cell lines. 5-FU: 5-Fluorouracil, Cur: curcumin.

Cell Lines	IC50 of 5-FU (mg/L)	IC50 of 5-FU under Cur (mg/L)	p Value
HT-29/shNC	131.81 ± 11.91	50.98 ± 4.21	0.023
HT-29/shNNMT	54.79 ± 4.39	29.95 ± 2.83	0.048
SW480/NC	15.52 ± 1.09	11.64 ± 1.06	0.110
SW480/NNMT	46.32 ± 1.66	18.2 ± 1.58	0.007