Table 2.
Histological scoring of control and NASH guinea pigs.
| Group | Control (n = 6) | NASH (n = 6) |
|---|---|---|
| Steatosis 1 | 0 | 3 ** |
| Ballooning 1 | 0 | 2 (1–2) * |
| Inflammation 1 | 0 (0–1) | 3 ** |
| Fibrosis 1 | 0 | 3 ** |
| Relative fibrosis area 2 | 1.39 ± 0.24 | 7.48 ± 1.81 *** |
Steatosis, Ballooning, inflammation, and fibrosis: medians with range (if applicable). Relative fibrosis area: means with standard deviations. Histopathological scoring data (steatosis, ballooning, inflammation, and fibrosis) is previously published [6]. 1 Analysed using Mann–Whitney U test. 2 Analysed by unpaired t-test with Welch’s correction. * p < 0.05, ** p < 0.01 and *** p < 0.001.