Table 3.
The summary of eight reported COVID-19 illness-associated loci
| SNP | Chr:BP | Locus | p value | A1 | 1KGP EAS Freq | 1KGP EUR Freq | A1 Freq | Mild Freq | Severe Freq |
|---|---|---|---|---|---|---|---|---|---|
| rs73064425 | 3:45901089 | LZTFL1 | / | T | 0.005 | 0.0795 | 0.005365 | 0.005882 | 0.005068 |
| rs9380142 | 6:29798794 | HLA-G | 0.846804 | G | 0.3492 | 0.3439 | 0.43133 | 0.4206 | 0.4375 |
| rs143334143 | 6:31121426 | CCHCR1 | 0.966751 | A | 0.0347 | 0.1123 | 0.059013 | 0.06176 | 0.05743 |
| rs3131294 | 6:32180146 | NOTCH4 | / | A | 0.0079 | 0.1133 | 0.006438 | 0.008824 | 0.005068 |
| rs10735079 | 12:113380008 | OAS1–OAS3 | 0.433044 | G | 0.252 | 0.3638 | 0.233906 | 0.2265 | 0.2382 |
| rs2109069 | 19:4719443 | DPP9 | 0.788196 | A | 0.1399 | 0.3211 | 0.143777 | 0.1382 | 0.147 |
| rs74956615 | 19:10427721 | TYK2 | / | / | / | / | / | / | / |
| rs2236757 | 21:34624917 | IFNAR2 | 0.4025 | G | 0.4345 | 0.7058 | 0.381974 | 0.3618 | 0.3936 |
A1 denotes the effect/alternate allele. 1KGP EAS Freq indicates the allele frequency in the EAS population from the 1KGP. Mild Freq indicates the allele frequency in patients from mild and moderate (grouped into mild) groups. Severe Freq indicates the allele frequency in patients from severe and critical (grouped into severe) groups.