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. 2021 Aug 31;7(3):132. doi: 10.3390/gels7030132

Table 3.

Numeric scales to evaluate tissue inflammatory response in groups (Pereira-Lucena et al., 2014) [9].

Score Cells Layers at the Margins of the Granulomas Inflammatory Reaction in the Host Tissue Inflammatory Response on the Mesh Surface Tissue Maturation
1 1–4 layers Non-dense, mature fibrous tissue Fibroblast without macrophages or foreign body cells Dense, mature interstitial tissue, similar to a normal connective or adipose tissue
2 5–9 layers Immature fibrous tissue with fibroblasts and little collagen Isolated foci or macrophages or foreign body cells Interstitial tissue with blood vessels, fibroblasts, and a few macrophages
3 10–30 layers Dense granular tissue with fibroblasts and many inflammatory cells One layer of macrophages foreign body cells Interstitial tissue with giant inflammatory cells but with permeating connective tissue
4 >30 layers Mass of inflammatory cells, with disorganized connective tissue Multiple layers of macrophages and foreign body cells Mass of inflammatory cells without permeating connective tissue