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. 2021 Jun 16;43(4):1683–1696. doi: 10.1007/s11357-021-00388-0

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Metabolomics of glycolysis and associated pathways. The glycolytic pathway is shown at center, with all metabolites that were measured highlighted in gray. Those metabolites that exhibited significant differences between groups (Fig. 2) are shown as bar graphs, using the same color scheme as Figs. 1 and 2. Graphs show means ± SEM of relative metabolite abundance (arbitrary units), with significant differences between groups indicated by asterisks