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CCL22 knockdown attenuated LPS-induced cartilage degradation of ATDC5 cells via CCR4. a–b The protein levels and mRNA expressions of MMP3, MMP9, MMP13, ADAMTS-4 and collagen II in LPS-stimulated ATDC5 cells were detected by Western blotting and RT-qPCR, respectively. c GAG expression in LPS-stimulated ATDC5 cells was detected by a GAG assay kit. *P < 0.05, **P < 0.01, ***P < 0.001
