Figure 4.

Absolute polyfunctional CMV-specific T-cell counts. Absolute polyfunctional CMV-specific CD4⁺ (top) and CD8⁺ (bottom) T-cell counts (defined by the phenotype IFN-γ plus ≥1 functional marker) at approximately day 90 after HCT in letermovir recipients and preemptive therapy recipients. Cytokine responses were generated after stimulation with CMV IE-1, pp65, and SEB (positive control) antigens. Violin plots show frequency distribution of data and width of sections represent the proportion of a specific value (ie, wider sections represent a greater proportion). Dotted lines represent the interquartile range and solid lines represent the median. Comparisons were made by Wilcoxon rank-sum tests.