Role of fasting duration and weekday in incretin and glucose regulation

The authors and journal apologise for errors in the above paper, which appeared in volume 9 part 4, pages 279–288. The errors relate to three values given in Table 2 on page 283. The value for Unadjusted upper 95% CI of 120 min plasma glucose should be 3.0, not 3.9, the value for Adjusted Estimate of Fasting plasma glucagon should be 0.0 not 0.3, and the value for Unadjusted Estimate of 30 min plasma GLP-1 should be −0.5 not −1.5. These errors do not affect the results or conclusions.

Table 2.

Back transformed (from log scale) estimates in percent difference for associations between overnight fasting duration and glucose, insulin, glucagon, GIP and GLP-1.

	Unadjusted			Adjusted for age, sex, BMI, smoking status and weekday
	n	Estimate (%), 95% CI	P	n	Estimate (%), 95% CI	P
Plasma glucose
Fasting	1717	0.0 (−0.4, 0.3)	0.844	1706	−0.2 (−0.5, 0.1)	0.267
30 min	1702	0.4 (−0.2, 0.9)	0.159	1691	0.2 (−0.3, 0.7)	0.488
120 min	1710	2.0 (1.1, 3.0)	<0.001	1699	1.7 (0.8, 2.5)	<0.001
rAUC0−30	1702	0.2 (0.0, 0.5)	0.068	1691	0.2 (0.0, 0.5)	0.109
rAUC0−120	1698	0.9 (0.5, 1.3)	<0.001	1687	0.8 (0.4, 1.2)	<0.001
Plasma insulin
Fasting	1716	1.6 (−0.3, 3.4)	0.094	1705	0.7 (−0.9, 2.2)	0.400
30 min	1699	1.3 (−0.6, 3.3)	0.172	1688	0.7 (−1.2, 2.5)	0.481
120 min	1708	4.8 (2.3, 7.2)	<0.001	1697	3.6 (1.4, 5.8)	0.001
rAUC0−30	1698	0.0 (−1.5, 1.4)	0.957	1687	0.2 (−1.2, 1.6)	0.805
rAUC0−120	1694	1.2 (−0.2, 2.7)	0.084	1683	1.3 (−0.1, 2.7)	0.066
Plasma glucagon
Fasting	1466	0.5 (−1.4, 2.5)	0.601	1455	0.0 (−1.8, 1.9)	0.967
30 min	1453	2.0 (0.0, 4.0)	0.048	1442	1.0 (−0.8, 2.9)	0.278
120 min	1457	−0.4 (−3.0, 2.3)	0.783	1446	−0.8 (−3.4, 1.9)	0.553
rAUC0−30	1450	0.2 (−0.5, 1.0)	0.579	1439	0.0 (−0.7, 0.8)	0.903
rAUC0−120	1442	0.2 (−0.9, 1.4)	0.720	1431	0.0 (−1.1, 1.2)	0.972
Plasma GIP
Fasting	1402	−2.6 (−4.3, −0.9)	0.003	1391	−2.4 (−4.1, −0.7)	0.006
30 min	1390	0.5 (−0.9, 1.9)	0.511	1380	0.5 (−0.9, 1.9)	0.468
120 min	1394	0.4 (−1.0, 1.8)	0.552	1383	0.7 (−0.7, 2.0)	0.328
rAUC0−30	1386	2.7 (1.2, 4.3)	<0.001	1376	2.6 (1.1, 4.1)	0.001
rAUC0−120	1377	3.0 (1.4, 4.7)	<0.001	1367	3.0 (1.3, 4.7)	0.001
Plasma GLP-1
Fasting	1464	−2.3 (−4.6, 0.0)	0.046	1453	−2.9 (−5.1, −0.6)	0.013
30 min	1453	−0.5 (−2.5, 1.5)	0.601	1442	−0.9 (−2.8, 1.0)	0.358
120 min	1457	−0.8 (−2.4, 0.9)	0.380	1446	−0.7 (−2.3, 0.9)	0.388
rAUC0−30	1448	1.4 (−0.5, 3.2)	0.149	1437	1.6 (−0.3, 3.4)	0.093
rAUC0−120	1440	1.9 (−0.2, 4.0)	0.073	1429	2.3 (0.3, 4.4)	0.026

Estimates are per 1 h increase in fasting duration. Linear regression models.

GIP, glucose-dependent insulinotropic polypeptide; GLP-1, glucagon-like peptide 1; rAUC_0–30, relative early response; rAUC_0–120, relative total response.

The correct Table 2 is given in full below: