Author response table 1. Twin Sensitivity Analysis: Association Between Telomere Length at Year 1 and Growth.
| Exposure | Outcome | N | 10th Percentile | 90th Percentile | Outcome, 90th Percentile v. 10th Percentile | |||
|---|---|---|---|---|---|---|---|---|
| Adjusted | ||||||||
| Predicted Outcome at 10th Percentile | Predicted Outcome at 90th Percentile | Coefficient (95% CI) | P-value | |||||
| Telomere length at Year 1 | LAZ Year 1 | 635 | 1.2 | 1.7 | -1.52 | -1.32 | 0.2 (0.02, 0.37) | 0.03* |
| WAZ Year 1 | 634 | 1.2 | 1.7 | -1.18 | -1.20 | -0.02 (-0.22, 0.19) | 0.89 | |
| WLZ Year 1 | 633 | 1.2 | 1.7 | -0.66 | -0.83 | -0.17 (-0.37, 0.03) | 0.10 | |
| HCZ Year 1 | 635 | 1.2 | 1.7 | -1.72 | -1.73 | -0.01 (-0.2, 0.18) | 0.92 | |
| LAZ Year 2 | 540 | 1.2 | 1.7 | -1.50 | -1.44 | 0.06 (-0.04, 0.16) | 0.21 | |
| WAZ Year 2 | 540 | 1.2 | 1.7 | -1.74 | -1.69 | 0.05 (-0.05, 0.16) | 0.35 | |
| WLZ Year 2 | 566 | 1.2 | 1.7 | -0.97 | -1.00 | -0.03 (-0.15, 0.08) | 0.58 | |
| HCZ Year 2 | 563 | 1.2 | 1.7 | -1.87 | -1.82 | 0.04 (-0.13, 0.21) | 0.65 | |
| Change in LAZ between Year 1 and Year 2 | 566 | 1.2 | 1.7 | -0.24 | -0.29 | -0.05 (-0.14, 0.05) | 0.35 | |
| Change in WAZ between Year 1 and Year 2 | 570 | 1.2 | 1.7 | -0.37 | -0.38 | -0.01 (-0.11, 0.09) | 0.87 | |
| Change in WLZ between Year 1 and Year 2 | 563 | 1.2 | 1.7 | -0.25 | -0.22 | 0.03 (-0.1, 0.17) | 0.66 | |
| Change in HCZ between Year 1 and Year 2 | 543 | 1.2 | 1.7 | -0.16 | -0.11 | 0.06 (-0.05, 0.17) | 0.32 | |
| Length velocity between Year 1 and Year 2 | 539 | 1.2 | 1.7 | 0.80 | 0.80 | 0 (-0.02, 0.03) | 0.76 | |
| Weight velocity between Year 1 and Year 2 | 539 | 1.2 | 1.7 | 0.15 | 0.15 | 0 (-0.01, 0.01) | 0.84 | |
| Head circumference velocity between Year 1 and Year 2 | 543 | 1.2 | 1.7 | 0.15 | 0.16 | 0.01 (0, 0.02) | 0.14 |
N, 10th Percentile, and 90th Percentile are from the adjusted analyses.
P-value < 0.05 after adjusting for multiple comparisons using the Benjamini-Hochberg procedure.