Table 3. Association between telomere length at Year 2 and growth.
Exposure | Outcome | N | 10th percentile | 90th percentile | Outcome, 90th percentile vs. 10th percentile | |||
---|---|---|---|---|---|---|---|---|
Adjusted* | ||||||||
Predicted outcome at 10th percentile | Predicted outcome at 90th percentile | Coefficient (95% CI) | p-value | |||||
Telomere length at Year 2 (T/S ratio) | LAZ Year 2 | 592 | 1.1 | 1.7 | −1.68 | −1.6 | 0.08 (−0.03, 0.19) | 0.17 |
WAZ Year 2 | 611 | 1.1 | 1.7 | −1.84 | −1.8 | 0.06 (−0.05, 0.16) | 0.3 | |
WLZ Year 2 | 615 | 1.1 | 1.7 | −0.98 | −1.1 | −0.08 (−0.2, 0.04) | 0.18 | |
HCZ Year 2 | 612 | 1.1 | 1.7 | −1.94 | −1.9 | 0 (−0.18, 0.17) | 0.98 | |
N, 10th percentile, and 90th percentile are from the adjusted analyses.
T/S ratio = unit for relative telomere length; LAZ = length-for-age Z score; WAZ = weight-for-age Z score; WLZ = weight-for-length Z score; HCZ = head circumference-for-age Z score.
Adjusted for pre-specified covariates: Child age, child sex, birth order, prior child length and weight measurements from Year 1, season of measurement, caregiver-reported diarrhoea, mother’s age, mother’s height, mother’s education level, mother’s Center for Epidemiologic Studies Depression Scale Revised (CESD-R) score, mother’s Perceived Stress Scale score, mother’s lifetime exposure to physical, sexual, and emotional intimate partner violence, household food insecurity, number of children <18 years in the household, number of individuals living in the compound, distance in minutes to the primary water source, household floor materials, household wall materials, household electricity, and household assets (wardrobe, table, chair, clock, khat, chouki, radio, television, refrigerator, bicycle, motorcycle, sewing machine, mobile phone, cattle, goats, and chickens), and treatment arm (control or N + WSH) (Supplementary file 1a).