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. 2021 Oct 6;598(7879):214–219. doi: 10.1038/s41586-021-03220-z

Fig. 1. Comprehensive transcriptional profiling of cell types across the mouse cerebellum.

Fig. 1

a, Experimental design with lobe-based sampling and profiling. AN, ansiform lobule; COP, copula pyramidis; CUL, culmen; F, flocculus; PF, paraflocculus; PRM, paramedian lobule; SIM, simple lobule. b, UMAP visualization of 611,034 nuclei (after profile quality control and annotation; Methods), coloured by cell type identity. ODC, oligodendrocyte; OPC, oligodendrocyte precursor cell. c, Dendrogram indicating hierarchical relationships between cell subtypes (left) with a paired dot plot (right) of scaled expression (exp.) of selected marker genes for cell type identity. Background text colours correspond to cell types in b. d, Allen Brain Atlas expression staining for selected gene markers of canonical cell populations, indicating cerebellar layer localization. GCL, granule cell layer; ML, molecular layer; PCL, Purkinje cell layer.