Abstract
The COVID-19 pandemic has induced large-scale behavioral changes, presenting a unique opportunity to study how air pollution is affected by societal shifts. At 455 PM monitoring sites across the United States, we conduct a causal inference analysis to determine the impacts of COVID-19 lockdowns on PM. Our approach allows for rigorous confounding adjustment with highly spatio-temporally resolved effect estimates. We find that, with the exception of the Southwest, most of the US experienced increases in PM compared to concentrations expected under business-as-usual. To investigate possible drivers of this phenomenon, we use a regression model to characterize the relationship of various factors with the observed impacts. Our findings have immense environmental policy relevance, suggesting that mobility reductions alone may be insufficient to substantially and uniformly reduce PM.
Keywords: COVID-19, Air pollution, Air quality, Stay-at-home, Environmental policy, Causal inference
1. Introduction
Acute widespread social, behavioral, and economic changes have occurred across the United States (US) in the wake of the COVID-19 pandemic. Most notably, mobility levels decreased substantially (Badr, Du, Marshall, Dong, Squire, Gardner, 2020, Jacobsen, Jacobsen, 2020, Lasry, Kidder, Hast, Poovey, Sunshine, Winglee, Zviedrite, Ahmed, Ethier, Clodfelter, Howard-Williams, Hulkower, Jeong, Landsman, McCord, Moreland, Shelburne, Billioux, Hand, Kanter, Smith, Sokol, Duchin, Fagalde, Pogosjans, Brown, Huang, Moss, Pan, Shemsu, Yette, Bock, Curtis-Robles, Lockett, Morrow, Sallenave, Santora, Willis, 2020) nationwide during the initial “lockdown period” in March and April 2020 as a result of changes in human behavior and other nonpharmaceutical interventions, such as government-imposed stay-at-home orders, in response to the rapid spread of the virus. The unprecedented actions taken to curb the spread of COVID-19 have created a unique “quasi-experiment” that can be leveraged to study the effect of large-scale behavioral change on air quality.
Exposure to fine particle matter, PM, has been shown to have significant adverse health effects, including respiratory and cardiovascular morbidity and mortality (Dominici, Peng, Bell, Pham, McDermott, Zeger, Samet, 2006, Pope, 2000, Xing, Xu, Shi, Lian, 2016). To create effective policy to limit PM exposure, it is crucial to understand the impact of reductions in certain emission-generating human behaviors on ambient concentrations. Studies of other, smaller scale quasi-experiments have provided some of the strongest evidence for the health impacts of air pollution and effective reduction strategies, e.g., the ban of bituminous coal in Dublin (Clancy et al., 2002), restrictions on transportation and industrial activities during the 1996 Atlanta (Friedman, 2001) and 2008 Beijing Olympic Games (Hou, An, Wang, Guo, 2010, Li, Wang, Kan, Xu, Chen, 2010).
A review of literature on the impacts of COVID-19 lockdowns on urban air pollution by Gkatzelis et al. (2021) identifies more than 200 published papers on the topic; however, the overwhelming majority of these studies were not conducted in the US. Among those that are US-focused, most have studied lockdown effects on air quality using data from a single or a few monitors (Chen et al., 2020) or using nationwide and/or statewide averages of monitored values (Shakoor et al., 2020). However, due to the vast differences across space in source-specific contributions to PM, the crudeness of these aggregated analyses limits their policy relevance. Several studies also utilize chemical transport models in their analyses (Barré, Petetin, Colette, Guevara, Peuch, Rouil, Engelen, Inness, Flemming, García-Pando, Bowdalo, Meleux, Geels, Christensen, Gauss, Benedictow, Tsyro, Friese, Struzewska, Kaminski, Douros, Timmermans, Robertson, Adani, Jorba, Joly, Kouznetsov, 2021, Menut, Bessagnet, Siour, Mailler, Pennel, Cholakian, 2020, Putaud, Pozzoli, Pisoni, Santos, Lagler, Lanzani, Santo, Colette, 2021), though these approaches make a number of assumptions that may not hold in practice. In our study, we estimate the effects of the lockdown on observed PM concentrations at each of 455 individual monitors in the Environmental Protection Agency (EPA) monitoring network located throughout the contiguous US. The high spatial resolution of our effect estimates, along with their basis in empirical data, provides more specific policy insights and enables deeper investigation into the factors influencing lockdown-related changes in PM.
While a monitor-level analysis of lockdown effects in the US has been published (Archer et al., 2020), our study aims to produce more robust effect estimates by employing causal inference methods. Even in the context of quasi-experimental conditions, isolating the effects of COVID-19 interventions on air pollution in general cannot be achieved through simple before-and-after comparisons, nor comparison to concentrations in the previous year(s), strategies that are used in much of the existing literature and oft-cited in news media. Numerous time-varying factors that influence air pollution levels, both observable and unobservable, are unaccounted for with such approaches, e.g., meteorology, year-to-year trends, and seasonality. For example, PM levels have decreased 44% in the US since 2000 (U.S. Environmental Protection Agency, 2020c). In their review, Gkatzelis et al. (2021) note that much of the available literature on lockdowns and air quality does not account for year-to-year variability and other time-varying factors that have a significant effect on air pollution. In the only existing monitor-level analysis in the US, Archer et al. (2020) compare observed PM concentrations to 5-year monthly average reference concentrations. As a result, more rigorous approaches are needed to account for pollution trends and time-varying confounders as a means of truly characterizing the causal effects of pandemic-related behavioral changes.
The aims of our study are best represented as a two-stage approach: first, we estimate the lockdown-attributable daily changes in PM concentrations at 455 monitoring sites using a causal inference approach that can adjust for both observed and unobserved time-varying contributors to PM. Formally, at each monitor, we estimate the PM concentrations that would have been expected each day in the absence of the COVID-19 pandemic and subsequent interventions (the “counterfactual”) and compare these to the corresponding observed levels at the monitor during the lockdown. Second, we use these effect estimates to identify environmental, geographical, mobility, and socioeconomic factors that are associated with changes in PM during the lockdown. We also quantify the impact of these short-term PM changes on respiratory and cardiovascular disease hospitalizations using the EPA’s Core Particulate Matter Health Impact Functions.
2. Materials and methods
All data preparation and analyses are conducted in R statistical software version 4.0.2.
For consistency, we define the “lockdown period” for each ground monitor site as beginning on the declared state of emergency for the corresponding contiguous US state (or District of Columbia) and ending on the earlier of either April 30, 2020 or on the day businesses began to reopen in that state (Raifman et al., 2020). The state-level lockdown period dates used throughout this study are given in Appendix Table A.1. Daily average PM concentrations between 2010 and 2019 from 1,580 monitor sites in the continental US are obtained from the EPA Air Quality System (AQS) (U.S. Environmental Protection Agency, 2020a). For 2020, daily average PM concentrations are obtained from the EPA AirNow system (U.S. Environmental Protection Agency, 2020a), where monitor data are made available prior to their integration into AQS, which occurs approximately twice per year. Daily meteorological factors (total precipitation, maximum temperature, maximum relative humidity, wind speed, and wind direction), day of the week, and season are obtained from Google Earth Engine (Gorelick et al., 2017), aggregated to the county level (for meteorology), and merged by county and day with the monitor-level PM data. Because some monitors have prohibitive amounts of missing PM measurements, we set inclusion criteria to select the monitors with sufficient data to establish the time trends needed for our analyses. Starting with 1,580 monitor sites with PM measurements between 2010–2020, we remove monitors (1) with no PM measurements during the defined lockdown period for their respective state, roughly mid-March to late-April of 2020 (918 monitors); (2) with less than 30 days of data during the lockdown period (23 monitors); (3) with no data prior to 2016 (117 monitors); or (4) with data entirely missing for five or more total years 2010–2019 (67 monitors). After applying these exclusion criteria, 455 monitors remain to be used in our analyses.
In our analysis, we rely solely on observed PM concentrations from ground monitors. Our goal is to estimate the daily PM concentrations that would have been expected at each monitoring site during the lockdown period under a business-as-usual scenario (i.e., without the lockdowns or the non-mandated personal behavioral changes that took place due to COVID-19 during the same period). Hereafter we refer to these as the “counterfactual PM concentrations”. As a result of long-term, seasonal and daily trends in PM, complex meteorological variability, and other potential unobserved confounding factors, PM concentrations from a single previous year cannot be directly utilized to infer the counterfactual PM concentrations, nor can a simple average of PM concentrations over multiple years of historical data. We therefore use a causal inference approach often referred to as the “synthetic control method” (SCM) to estimate counterfactual PM concentrations (Abadie, Diamond, Hainmueller, 2010, Athey, Bayati, Doudchenko, Imbens, Khosravi, Xu, 2017).
SCM was created to analyze the effects of a policy or intervention on an outcome in the context of case studies. It leverages time series containing pre- and post-intervention outcome data from (1) a single unit that received an intervention (the “treated” unit) and (2) a set of control units that did not receive the intervention. Conceptually, using the pre-intervention data from both treated and control units, it creates a weighted average of the time series from the control units that best captures the pre-intervention trends in the time series for the treated unit. Then that same weighted average of the control units’ outcomes is used to estimate the outcome that would have been expected in the treated unit during the post-treatment period, in the absence of the intervention (the counterfactual outcome). This weighted average created by SCM is called a “synthetic control”. Formally, the optimal weights are identified by obtaining a latent factor representation of the multivariate time series data. SCM is flexible enough to account for both time-varying and time-invariant confounders of the intervention effect under mild assumptions. In addition, it accounts for any remaining pre-treatment missing data by imputation. Xu (2017) conducted a number of simulations demonstrating the superior performance of SCM over other commonly used estimators in quasi-experimental settings, such as the difference-in-differences estimator that is used in a number of studies of lockdown effects on air pollution (He, Pan, Tanaka, 2020, Liu, Wang, Zheng, 2021).
Adapting the SCM framework to our application, for a given monitor, we consider each year 2010–2020 to be a “unit”, and the time series of PM concentrations for each year (limited to months January-April) are the outcomes. 2020 is considered the treated unit and all other years are controls. Thus, SCM will create a weighted average of daily 2010–2019 PM concentrations at that monitor, and use that weighted average to estimate the counterfactual daily PM concentrations during the lockdown period. The weights are selected to result in a synthetic 2020 time series that provides the closest approximation of the 2020 pre-lockdown observed time series of PM concentrations.
To create a proper synthetic control, we must ensure that the time series from each year are aligned so that the day represented at a given position in the time series is comparable across years. Because PM exhibits weekday and weekend trends that must be accounted for when creating the synthetic control, we align the time series based on day-of-week rather than day-of-year. In particular, we let the time series for each year start on the first Monday of the year, so that aligning entries in the time series represent the same day-of-week and only a few days difference in day-of-year. The values of the synthetic times series during the lockdown represent our best guess at what PM concentrations would have been under a “business-as-usual” scenario, simultaneously accounting for daily, seasonal, and long-term PM trends.
We implement SCM separately on the data from each of the 455 monitors using the gsynth package in R (Xu, 2017) with a matrix completion estimator (Athey et al., 2020). In addition to the default latent factor representation used by SCM, we include in the model fixed effects for year and time series position and adjust for both weather (maximum temperature, maximum relative humidity, precipitation, wind speed, and wind direction) and seasonality (month of year) as time-varying covariates. At each monitor, we take the simple difference of the observed PM concentrations during the lockdown and the SCM-estimated counterfactual PM concentrations to obtain the lockdown-attributable changes in PM for each day. Cumulative estimates of lockdown-attributable changes in PM reported hereafter are averages of these daily effect estimates across all days in the lockdown period for the specified monitor. For consistency with the causal inference literature, we refer to these estimates as “average treatment effects on the treated” (ATTs).
Diagnostic plots are manually inspected for each monitor to assess SCM model fit. In addition, we conduct a formal evaluation of the accuracy of the SCM method relative to another commonly used approach for lockdown air quality effect estimation (Gkatzelis et al., 2021). First, we refit our SCM models for each monitor, removing all 2020 data and designating 2019 as a fabricated treated unit, and use SCM to predict PM concentrations in the 2019 post-treatment period (mid-March through the end of April to seasonally align with the 2020 lockdown period). As no major nationwide behavioral shifts occurred at this time in 2019, small differences between predicted and observed PM concentrations indicate strong model performance. For comparison, for each monitor, we also created predictions of PM for the fabricated treated unit by taking a simple average of concentrations during the same period over the preceding 3 years (2016–2018), which is a commonly-used approach for performing these types of analyses. We compare both sets of predictions with the empirical PM concentrations observed in 2019, and we compute the root mean square error (RMSE) at each monitor.
In the second stage of modeling, we use a linear regression model to identify features associated with the estimated lockdown-attributable changes in PM. The effect of meteorological variables adjusted for in the first stage of modeling is first subtracted from the treatment effect estimates, to remove any influence of unusual meteorology on changes in PM during lockdown. Each monitor is then linked to a large set of features of the county it resides in. The units of analysis in this model are monitors, and the outcome in the regression model is the monitor-level estimated lockdown-attributable change in PM. Features included as predictors in the model are: residential emissions, industrial processes emissions, industrial boiler emissions, dust emissions, agriculture emissions, mobile emissions, mobility change relative to baseline, socioeconomic and demographic variables (proportion of population age 65+, racial composition, poverty rate, population density), urbanization level (classified into large central metro, large fringe metro, medium metro, and other), and US census-defined regions (Midwest, Northwest, South, and West). All features are obtained at the county-level and each monitor is assigned the features of the county in which it lies. Descriptions of each variable and data sources are provided in Appendix Table A.2.
Mobility change was measured relative to a February 2020 baseline and defined by quantifying the number of Bing tiles Facebook users are seen in during a day (Herdaǧdelen et al., 2020). Socioeconomic and demographic variables were taken from the 2018 5-year American Community Survey (U.S. Census Bureau, 2019). Data on sources of emissions were obtained from the EPA 2017 National Emissions Inventory reports (U.S. Environmental Protection Agency, U.S. Environmental Protection Agency). Urban-rural classifications are obtained from 2013 National Center for Health Statistics Urban-Rural Classification Scheme for Counties (Ingram and Franco, 2012) and large central metro is used as the reference variable in the model. Areas classified as smaller than “medium metro” are grouped into a variable called “other”. The Midwest Region is the reference variable in the model for region indicators. Coefficient estimates and 95% confidence intervals are reported.
We use exposure-response functions from the EPA’s Core Health Impact Functions for Particulate Matter and Hospital Admissions (U.S. Environmental Protection Agency, 2020b) to characterize associations between short-term PM exposure and (1) respiratory disease hospitalization risk and (2) cardiovascular disease hospitalization risk (Bell, 2012, Kloog, Coull, Zanobetti, Koutrakis, Schwartz, 2012). To estimate the health impacts of lockdown-attributable PM changes across the entire continental US, we first interpolate the estimated monitor-level PM changes to obtain an estimate for each county (including those without an included monitor). Inverse distance weighting is used to interpolate the estimated effects at the monitor sites to each county’s centroid, and the resulting interpolated values are treated as each county’s lockdown-attributable change in PM. We insert each county’s PM changes into the pre-existing short-term exposure-response functions for each hospitalization type for individuals 65+ (a log-linear model with parameter estimates taken from Kloog et al. (2012) and Bell (2012)) to obtain an estimate of its change in hospitalization incidence rate. Baseline incidence rates are calculated using a weighted average of hospitalization incidence rates for people age 65+ (3.352 respiratory hospitalizations/100 people per year; 5.385 cardiovascular hospitalizations/100 people per year). The change in incidence rate is then used to obtain the county’s absolute change in hospitalizations for each of the two health outcomes in people age 65+. These values are summed across each US census region and scaled to account for the number of days in the state’s lockdown period, i.e., the number of days of the specified change in PM exposure. We also estimate the changes in hospitalization incidence that would have occurred if these PM changes had been sustained for an entire year.
3. Results and discussion
For each ground monitor, we use SCM to estimate the “counterfactual PM concentrations” during the corresponding defined lockdown period, i.e., the daily concentrations that would have been expected during the 2020 lockdown period in the absence of the lockdown or any non-mandated personal behavioral changes that took place due to COVID-19 during same period. The counterfactual concentrations are then used to obtain the estimated lockdown-attributable changes in PM concentrations (ATTs) at each monitor. Fig. 1 maps the ATTs at each monitoring site as well as showing a smoothed map of these estimates, interpolated using inverse distance weighting. Negative ATT values, depicted in green, indicate that the location experienced a lockdown-attributable decrease in PM concentrations, while positive (orange/red) values represent lockdown-attributable increases.
We find that, during the COVID-19 lockdowns, PM increased across most of the US compared to what would have been expected under a business-as-usual scenario. We henceforth refer to smaller lockdown-attributable increases or larger lockdown-attributable decreases as “smaller increases”, and larger lockdown-attributable increases or smaller lockdown-attributable decreases as “larger increases”. The maps suggest that any lockdown-attributable decreases in PM are generally limited to areas of the Western and Southwestern United States. However, substantial lockdown-attributable increases were observed in much of the South, Midwest, and Pacific Northwest. Stratifying by US Census-defined regions, we find average region-wide increases of 1.19 µg/m, 1.11 µg/m, 1.94 µg/m, and 0.80 µg/m for the Northeast, South, Midwest, and West, respectively. Over the entire country, we observe an average increase of 1.36 µg/m attributable to pandemic interventions.
Monitor-level model fit plots indicate that the synthetic controls created by SCM are effectively capturing 2020 pre-lockdown PM trends (Appendix Figure A.3). The results of our assessment of SCM predictive accuracy for 2019 are displayed in Appendix Figure A.1. The blue histogram shows the distribution of the monitor-level RMSEs for SCM predictions (gsynth) and the red histogram shows the monitor-level RMSEs for the historic 3-year averaging method. The lower RMSEs for SCM indicate improved predictive performance and better ability to capture trends in PM relative to simple historic averaging.
The formation of PM is known to be a very complex process– along with being directly emitted, much of it is formed secondarily in the atmosphere from other pollutants. To better understand factors that may have contributed to the heterogeneity in lockdown-attributable PM changes detected by our study (Fig. 1), we investigate associations between the monitor-level effect estimates and the environmental, geographical, regional, meteorological, mobility, and socioeconomic conditions in the area surrounding the monitor. Using the estimated lockdown-attributable PM changes as the outcome, we fit a linear regression model. Using this model, we find that historic industrial boiler emissions and county population density have significant positive associations with lockdown-attributable increases in PM, while a significant negative association was observed for relative mobility decrease, proportion of population age 65+, and the West region (relative to the reference region Midwest). In addition, relative to the most urban counties (reference group), all less urban county classifications show significant positive associations with lockdown-attributable increases in PM. A summary of model estimates is provided in Fig. 2 .
Although areas with larger decreases in mobility tended to experience smaller increases in PM, our results suggest that any positive air quality impacts of these large-scale mobility decreases were, on average, insufficient to offset other non-meteorological factors promoting PM formation. Supporting this finding is Table 1 , which shows the amount of PM emissions for each US Census region stratified by source (U.S. Environmental Protection Agency, 2014). Regions with historically higher emissions from stationary sources (i.e. fuel combustion sources such as power plants, solvents, agriculture, and other industrial processes) correspond to areas in which we found higher propensity for lockdown-attributable increases in PM during the lockdown. Additionally, mobile sources have a comparatively much smaller impact on PM emissions (Table 1).
Table 1.
Type | Northeast | South | Midwest | West | US Total |
---|---|---|---|---|---|
Stationary | 260,853 (82.7%) | 1,181,440 (60.9%) | 1,262,981 (81.1%) | 568,122 (42.4%) | 3,273,396 (63.5%) |
Mobile | 41,432 (13.1%) | 129,699 (6.9%) | 97,710 (6.3%) | 64,945 (4.9%) | 333,786 (6.5%) |
Other | 13,091 (4.2%) | 629,734 (32.4%) | 196,898 (12.6%) | 705,595 (52.7%) | 1,545,318 (30.0%) |
We also investigate these lockdown-attributable PM changes relative to a “baseline” PM level prior to the pandemic. For each monitor site, we calculate the baseline as the average PM concentration observed in the month of April for 2017–2019. In a linear model, we find a nonsignificant, negative association (-0.076, 95% CI [-0.165, 0.014]) between baseline PM and the estimated lockdown-attributable changes in PM.
Additionally, we assess the sensitivity of our findings to a 1–2 day spike in PM of unknown origin that we observed during the lockdown period for many monitors in the Midwest. To do so, we identify and remove these outlier days, defined as days on which PM levels spiked to 35 or higher, from our ATT estimates for all monitors. However, the removal of these outliers did not significantly affect the results (see Appendix Figure A.2).
We calculate the expected impacts of the estimated lockdown-attributable changes in PM on respiratory and cardiovascular disease hospitalizations in the age 65+ population for each county in the US, using the EPA’s Core Health Impact Functions for Particulate Matter (U.S. Environmental Protection Agency, 2020b). We sum these changes across counties within each US region to obtain the results displayed in Table 2 . The values in Table 2 are thus estimates of the net change in hospitalizations over the given US Census region which would be expected due to our previously estimated lockdown-attributable PM changes. For example, we estimate that there was a net increase of 83 respiratory disease hospitalizations over the entire Midwest region during the lockdown period, and a net decease of 14 respiratory disease hospitalizations over the West region during the same time period. As a reference, estimated baseline hospitalizations are given in Appendix Table A.3. However, we acknowledge that the usage of these dose-response functions cannot not fully characterize the complexity involved in estimating the health effects of PM and that such usage requires a number of simplifying assumptions. Although they are not estimated from empirical health data and involve strong assumptions, health impact estimates from dose-response functions are commonly considered in the environmental policy/cost-benefit analysis context, which motivates their inclusion here. These estimates are small relative to the overall PM burden in the US (Murray et al., 2020), as expected given the short time-scale and the varying directions of the PM changes.
Table 2.
Region | Respiratory (LD) | CVD (LD) | Respiratory (Yearly) | CVD (Yearly) |
---|---|---|---|---|
Northeast | 35 | 64 | 256 | 469 |
South | 57 | 105 | 416 | 764 |
Midwest | 83 | 153 | 609 | 1117 |
West | -14 | -26 | -104 | -191 |
US Total | 161 | 296 | 1177 | 2160 |
There are a number of limitations of our study. First, due to sporadic data collection at certain monitor sites, there is a considerable amount of missing PM data, particularly in prior years that are used to establish expected PM in the absence of the lockdown. However, much of the missingness is by-design due to EPA monitoring procedures, and we have set fairly stringent monitor inclusion criteria for our analyses to ensure that observed data are sufficient to capture important trends. In addition, our models are flexible enough to account for some missing data and we have visually inspected our results to ensure suitable model fit pre-lockdown (Appendix Figure A.3) as well as conducted a formal evaluation demonstrating the predictive accuracy of our model as described in the Methods (Appendix Figure A.1). Furthermore, the heterogeneity of lockdown procedures, stringency, and adherence to advisories creates difficulty in a clear definition of the lockdown period. However, the time period we have defined was the period of the most acute lockdowns and we have further mitigated this issue by using consistent criteria for each state.
Additionally, we note that total PM is only one aspect of air pollution that is relevant to human health. While we report lockdown-attributable increases in total PM concentrations in many areas of the US, lockdown-attributable decreases in other pollutants such as NO and in certain PM components, as found in other studies (Berman, Ebisu, 2020, Chen, Chien, Li, Lin, 2020), demonstrate that reductions in mobile-source emissions were effective in decreasing certain other hazardous pollutants. The scope of this study also does not examine the changes in overall emissions during lockdown compared to business-as-usual; rather, we investigate the relationship between an area’s historical emissions and their estimated changes in PM during lockdown. Future work will include investigation of changes in emissions due to lockdowns and the downstream effects on air pollution.
Our study has found that the impacts of the 2020 COVID-19 lockdowns on PM levels vary dramatically across the US, with strong regional trends. In the Midwestern and Southern regions, we unexpectedly observe consistent increases in PM compared to expected levels absent the lockdowns, while some areas in the Southwest experienced substantial decreases. One possible reason for this result is that PM in the US is mostly attributed to industrial processes, electricity generation, and dust (Chen et al., 2020), which may have been minimally affected by the COVID-19 lockdowns. This is consistent with the results of several other studies in the US (Archer, Cervone, Golbazi, Fahel, Hultquist, 2020, Bekbulat, Apte, Millet, Robinson, Wells, Presto, Marshall, 2021, Berman, Ebisu, 2020, Chen, Chien, Li, Lin, 2020) which find either no change or increases in PM over the lockdown period. The reasons behind these trends are undoubtedly intricate given the complex nature of PM formation and a full investigation of these reasons is beyond the scope of this paper.
The results of this important quasi-experiment provide evidence that policies to limit individual-level emissions-generating behaviors like mobility may not, alone, reduce total PM levels, particularly in certain regions and when accompanied by other social and economic changes. Reduction of emissions from stationary sources may be necessary to meaningfully and uniformly reduce PM and improve human health.
Author contributions: KLC led all data preparation, conducted all statistical analyses, and prepared a first draft of the manuscript. LRFH provided expertise in air pollution and atmospheric chemistry and assisted with manuscript preparation. RCN assisted with idea generation and study design, aided in data acquisition and preparation, provided statistical input, and assisted with manuscript preparation.
Data and materials availability: Requests for materials should be addressed to Rachel Nethery at rnethery@hsph.harvard.edu.
Declaration of Competing Interest
Authors declare that they have no competing interests.
Acknowledgements
Funding: This work was supported by the National Institutes of Health [grant numbers T32ES007142, 1K01ES032458-01, R01AG060232].
Footnotes
Supplementary material associated with this article can be found, in the online version, at 10.1016/j.envadv.2021.100122.
Appendix A. Supplementary materials
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References
- Abadie A., Diamond A., Hainmueller J. Synthetic control methods for comparative case studies: estimating the effect of California’s tobacco control program. J. Am. Stat. Assoc. 2010;105(490):493–505. [Google Scholar]
- Archer C.L., Cervone G., Golbazi M., Fahel N.A., Hultquist C. Changes in air quality and human mobility in the USA during the COVID-19 pandemic. Bull. Atmos. Sci. Technol. 2020;1(3–4):491–514. doi: 10.1007/s42865-020-00019-0. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Athey, S., Bayati, M., Doudchenko, N., Imbens, G., Khosravi, K., 2020. Matrix completion methods for causal panel data models. 1710.10251.
- Badr H.S., Du H., Marshall M., Dong E., Squire M.M., Gardner L.M. Association between mobility patterns and COVID-19 transmission in the USA: a mathematical modelling study. Lancet Infect. Dis. 2020 doi: 10.1016/s1473-3099(20)30553-3. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Barré J., Petetin H., Colette A., Guevara M., Peuch V.-H., Rouil L., Engelen R., Inness A., Flemming J., García-Pando C.P., Bowdalo D., Meleux F., Geels C., Christensen J.H., Gauss M., Benedictow A., Tsyro S., Friese E., Struzewska J., Kaminski J.W., Douros J., Timmermans R., Robertson L., Adani M., Jorba O., Joly M., Kouznetsov R. Estimating lockdown-induced european NO2 changes using satellite and surface observations and air quality models. Atmos. Chem. Phys. 2021;21(9):7373–7394. doi: 10.5194/acp-21-7373-2021. [DOI] [Google Scholar]
- Bekbulat B., Apte J.S., Millet D.B., Robinson A.L., Wells K.C., Presto A.A., Marshall J.D. Changes in criteria air pollution levels in the US before, during, and after covid-19 stay-at-home orders: evidence from regulatory monitors. Sci. Total Environ. 2021;769:144693. doi: 10.1016/j.scitotenv.2020.144693. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Bell M.L. Assessment of the health impacts of particulate matter characteristics. Res Rep Health Eff Inst. 2012;(161):5–38. [PubMed] [Google Scholar]
- Berman J.D., Ebisu K. Changes in U.S. air pollution during the COVID-19 pandemic. Sci. Total Environ. 2020;739:139864. doi: 10.1016/j.scitotenv.2020.139864. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Chen L.-W.A., Chien L.-C., Li Y., Lin G. Nonuniform impacts of COVID-19 lockdown on air quality over the United States. Sci. Total Environ. 2020;745:141105. doi: 10.1016/j.scitotenv.2020.141105. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Clancy L., Goodman P., Sinclair H., Dockery D.W. Effect of air-pollution control on death rates in Dublin, Ireland: an intervention study. Lancet. 2002;360(9341):1210–1214. doi: 10.1016/s0140-6736(02)11281-5. [DOI] [PubMed] [Google Scholar]
- Dominici F., Peng R.D., Bell M.L., Pham L., McDermott A., Zeger S.L., Samet J.M. Fine particulate air pollution and hospital admission for cardiovascular and respiratory diseases. JAMA. 2006;295(10):1127. doi: 10.1001/jama.295.10.1127. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Friedman M.S. Impact of changes in transportation and commuting behaviors during the 1996 Summer Olympic Games in Atlanta on air quality and childhood asthma. JAMA. 2001;285(7):897. doi: 10.1001/jama.285.7.897. [DOI] [PubMed] [Google Scholar]
- Gkatzelis G.I., Gilman J.B., Brown S.S., Eskes H., Gomes A.R., Lange A.C., McDonald B.C., Peischl J., Petzold A., Thompson C.R., Kiendler-Scharr A. The global impacts of COVID-19 lockdowns on urban air pollution. Elem. Sci. Anth. 2021;9(1) doi: 10.1525/elementa.2021.00176. [DOI] [Google Scholar]
- Gorelick N., Hancher M., Dixon M., Ilyushchenko S., Thau D., Moore R. Google earth engine: planetary-scale geospatial analysis for everyone. Remote Sens. Environ. 2017 doi: 10.1016/j.rse.2017.06.031. [DOI] [Google Scholar]
- He G., Pan Y., Tanaka T. The short-term impacts of COVID-19 lockdown on urban air pollution in China. Nat. Sustain. 2020;3(12):1005–1011. doi: 10.1038/s41893-020-0581-y. [DOI] [Google Scholar]
- Herdaǧdelen, A., Dow, A., State, B., Mohassel, P., Pompe, A., 2020. Protecting privacy in facebook mobility data during the COVID-19 response. https://research.fb.com/blog/2020/06/protecting-privacy-in-facebook-mobility-data-during-the-covid-19-response/.
- Hou Q., An X., Wang Y., Guo J. An evaluation of resident exposure to respirable particulate matter and health economic loss in Beijing during Beijing 2008 Olympic Games. Sci. Total Environ. 2010;408(19):4026–4032. doi: 10.1016/j.scitotenv.2009.12.030. [DOI] [PubMed] [Google Scholar]
- Ingram D.D., Franco S.J. NCHS urban-rural classification scheme for counties. Vital Health Stat 2. 2012;(154):1–65. [PubMed] [Google Scholar]
- Jacobsen G.D., Jacobsen K.H. Statewide COVID-19 stay-at-home orders and population mobility in the United States. World Med. Health Policy. 2020 doi: 10.1002/wmh3.350. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Kloog I., Coull B.A., Zanobetti A., Koutrakis P., Schwartz J.D. Acute and chronic effects of particles on hospital admissions in New-England. PLoS ONE. 2012;7(4):e34664. doi: 10.1371/journal.pone.0034664. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lasry A., Kidder D., Hast M., Poovey J., Sunshine G., Winglee K., Zviedrite N., Ahmed F., Ethier K.A., Clodfelter C., Howard-Williams M., Hulkower R., Jeong G., Landsman L., McCord R., Moreland A., Shelburne J., Billioux A., Hand J., Kanter J., Smith A., Sokol T., Duchin J.S., Fagalde M.S., Pogosjans S., Brown R., Huang S., Moss N., Pan E., Shemsu M., Yette E., Bock C., Curtis-Robles R., Lockett C., Morrow S., Sallenave C., Santora L., Willis M. Timing of community mitigation and changes in reported COVID-19 and community mobility– Four U.S. metropolitan areas. MMWR Morb. Mortal. Wkly. Rep. 2020;69(15):451–457. doi: 10.15585/mmwr.mm6915e2. [DOI] [PMC free article] [PubMed] [Google Scholar]; February 26–April 1, 2020
- Li Y., Wang W., Kan H., Xu X., Chen B. Air quality and outpatient visits for asthma in adults during the 2008 Summer Olympic Games in Beijing. Sci. Total Environ. 2010;408(5):1226–1227. doi: 10.1016/j.scitotenv.2009.11.035. [DOI] [PubMed] [Google Scholar]
- Liu F., Wang M., Zheng M. Effects of COVID-19 lockdown on global air quality and health. Sci. Total Environ. 2021;755:142533. doi: 10.1016/j.scitotenv.2020.142533. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Menut L., Bessagnet B., Siour G., Mailler S., Pennel R., Cholakian A. Impact of lockdown measures to combat COVID-19 on air quality over Western Europe. Sci. Total Environ. 2020;741:140426. doi: 10.1016/j.scitotenv.2020.140426. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Murray C.J.L., Aravkin A.Y., Zheng P., Abbafati C., Abbas K.M., Abbasi-Kangevari M., Abd-Allah F., Abdelalim A., Abdollahi M., Abdollahpour I., Abegaz K.H., Abolhassani H., Aboyans V. Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the global burden of disease study 2019. Lancet. 2020;396(10258):1223–1249. doi: 10.1016/s0140-6736(20)30752-2. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pope C.A. Epidemiology of fine particulate air pollution and human health: biologic mechanisms and who’s at risk? Environ. Health Perspect. 2000;108(suppl 4):713–723. doi: 10.1289/ehp.108-1637679. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Putaud J.-P., Pozzoli L., Pisoni E., Santos S.M.D., Lagler F., Lanzani G., Santo U.D., Colette A. Impacts of the COVID-19 lockdown on air pollution at regional and urban background sites in Northern Italy. Atmos. Chem. Phys. 2021;21(10):7597–7609. doi: 10.5194/acp-21-7597-2021. [DOI] [Google Scholar]
- Raifman, J., Nocka, K., Jones, D., Bor, J., Lipson, S., Jay, J., Chan, P., 2020. COVID-19 US state policy database. Available at: www.tinyurl.com/statepolicies.
- Shakoor A., Chen X., Farooq T.H., Shahzad U., Ashraf F., Rehman A., e Sahar N., Yan W. Fluctuations in environmental pollutants and air quality during the lockdown in the USA and China: two sides of COVID-19 pandemic. Air Qual. Atmos. Health. 2020:1–8. doi: 10.1007/s11869-020-00888-6. [DOI] [PMC free article] [PubMed] [Google Scholar]
- U.S. Census Bureau, 2019. 2014–2018 American Community Survey 5-Year Estimates. Prepared by Social Explorer.
- U.S. Environmental Protection Agency, 2014. National emissions inventory. https://www.epa.gov/air-emissions-inventories/2014-national-emissions-inventory-nei-data.
- U.S. Environmental Protection Agency, 2017. National emissions Inventory. https://www.epa.gov/air-emissions-inventories/2017-national-emissions-inventory-nei-data.
- U.S. Environmental Protection Agency, 2020a. Air quality system data mart. http://www.epa.gov/ttn/airs/aqsdatamart.
- U.S. Environmental Protection Agency, 2020b. Environmental benefits mapping and analysis program - community edition.
- U.S. Environmental Protection Agency, 2020c. Our Nation’s Air 2020. https://gispub.epa.gov/air/trendsreport/2020.
- Xing Y.-F., Xu Y.-H., Shi M.-H., Lian Y.-X. The impact of PM2.5 on the human respiratory system. J. Thorac. Dis. 2016;8(1) doi: 10.3978/j.issn.2072-1439.2016.01.19. [DOI] [PMC free article] [PubMed] [Google Scholar]; http://jtd.amegroups.com/article/view/6353
- Xu Y. Generalized synthetic control method: causal inference with interactive fixed effects models. Polit. Anal. 2017;25(1):57–76. doi: 10.1017/pan.2016.2. [DOI] [Google Scholar]
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