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. 2021 Sep 28:taab154. doi: 10.1093/jtm/taab154

Comparable neutralization of SARS-CoV-2 Delta AY.1 and Delta with individuals sera vaccinated with BBV152

Pragya D Yadav 1,, Rima R Sahay 2, Gajanan Sapkal 3, Dimpal Nyayanit 4, Anita M Shete 5, Gururaj Deshpande 6, Deepak Y Patil 7, Nivedita Gupta 8, Sanjay Kumar 9, Priya Abraham 10, Samiran Panda 11, Balram Bhargava 12
PMCID: PMC8500129  PMID: 34581415

Abstract

Sera of COVID-19 naive vaccinees, COVID-19 recovered cases with vaccination and breakthrough cases demonstrated 1.3, 2.5 and 1.9-fold reduction in neutralization titers against Delta and 1.5, 3.5, 2.8-fold against Delta AY.1 compared to B.1 respectively. However, high neutralization titers would still effectively protect against Delta, Delta AY.1 and B.1.617.3 variants.

Keywords: BBV152, Neutralization, Delta AY.1, Delta, Variant of concern, SARS-CoV-2


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