Figure 5.
P18 and P40 hippocampal volumes (in mm3) including DG and CA regions. A, IUGR decreased P18 hippocampal volumes in both males and females compared with sex-matched sham controls. p = 0.024, IUGR compared with sham controls. B, IUGR also decreased P40 hippocampal volumes in both males and females compared with sex-matched shams. p = 0.0007, IUGR mice compared with sham controls. Sex differences in hippocampal volumes are shown to the right of A and B. Two-way ANOVA with Tukey’s HSD post hoc test was used to examine the effects of treatment (sham or IUGR), sex, or both sex and treatment on hippocampal volumes.