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. 2021 Jun 22;46(12):2180–2187. doi: 10.1038/s41386-021-01072-9

Fig. 4. Mediation analysis.

Fig. 4

No significant direct effect of global mean FMM SUVR values on HAMD17 total scores (β = 0.08, p = 0.44) were noted. Effect of global mean FMM SUVR values on the HAMD17 total scores was mediated by subgenual ACC FC values within the anterior DMN (β = 0.27, p = 0.002). Ant Anterior, CERAD Korean version of the Consortium to Establish a Registry for Alzheimer’s Disease, Dep Depression group, DMN Default Mode Network, FC Functional Connectivity, Post Posterior.