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. 2021 Sep 24;26(19):5785. doi: 10.3390/molecules26195785

Figure 5.

Figure 5

Total cell number and cell viability of KG-1a, KG-1, and EoL-1 cells after treatment with Dox and combination of fixed concentration of Dox and various non-toxic concentration of Cur for 48 h. Total cell number (A) and cell viability (B) of KG-1a cells were treated with DMSO (VC), Dox (15 ng/mL), Dox + Cur (4 µg/mL), Dox + Cur (4.5 µg/mL), and Dox + Cur (5 µg/mL) for 48 h. Total cell number (C) and cell viability (D) of KG-1 cells were treated with DMSO (VC), Dox (22 ng/mL), Dox and Cur (3 µg/mL), Dox and Cur (3.5 µg/mL), and Dox and Cur (4 µg/mL) for 48 h. Total cell number (E) and cell viability (F) of EoL-1 cells were treated with DMSO (VC), Dox (2.8 ng/mL), Dox and Cur (2.5 µg/mL), Dox and Cur (3 µg/mL), and Dox and Cur (3.5 µg/mL) for 48 h. The data are shown as mean ± SD from 3 independent experiments. The significance of mean differences was assessed using one-way ANOVA. * p < 0.05, ** p < 0.01, and *** p < 0.001 compared with VC. # p < 0.05 and ## p < 0.01 compared with single-Dox treatment.