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. 2021 Oct 12;10(10):67. doi: 10.1038/s41389-021-00356-5

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — A TRPC1 knockdown inhibited the invasive and migratory capabilities of SW620 cells. Typical results are shown in the upper panel along with the statistical analysis in the lower panel (n = 5). B Overexpression of TRPC1 facilitated the invasive and migratory capabilities of SW620 cells (n = 5). C Images of lung metastasis in nude mice inoculated with vector or TRPC1 overexpressed SW620 cells (n = 4). D Representative H&E stained lung metastases tissues of nude mice. Images were observed under 100× magnification. **P < 0.01.