Lower Extremity Musculoskeletal Injury in US Military Academy Cadet Basic Training: A Survival Analysis Evaluating Sex, History of Injury, and Body Mass Index

Abstract

Background:

Injury incidence for physically active populations with a high volume of physical load can exceed 79%. There is little existing research focused on timing of injury and how that timing differs based on certain risk factors.

Purpose/Hypothesis:

The purpose of this study was to report both the incidence and timing of lower extremity injuries during cadet basic training. We hypothesized that women, those with a history of injury, and those in underweight and obese body mass index (BMI) categories would sustain lower extremity musculoskeletal injury earlier in the training period than men, those without injury history, and those in the normal-weight BMI category.

Study Design:

Cohort study; Level of evidence, 2.

Methods:

Cadets from the class of 2022, arriving in 2018, served as the study population. Baseline information on sex and injury history was collected via questionnaire, and BMI was calculated from height and weight taken during week 1 at the United States Military Academy. Categories were underweight (BMI <20), middleweight (20-29.99), and obese (≥30). Injury surveillance was performed over the first 60 days of training via electronic medical record review and monitoring. Kaplan-Meier survival curves were used to estimate group differences in time to the first musculoskeletal injury. Cox proportional hazard regression was used to estimate hazard ratios (HRs).

Results:

A total of 595 cadets participated. The cohort was 76.8% male, with 29.9% reporting previous injury history and 93.3% having a BMI between 20 and 30. Overall, 16.3% of cadets (12.3% of male cadets and 29.7% of female cadets) experienced an injury during the follow-up period. Women experienced significantly greater incident injury than did men (P < .001). Separation of survival curves comparing the sexes and injury history occurred at weeks 3 and 4, respectively. Hazards for first musculoskeletal injury were significantly greater for women versus men (HR, 2.63; 95% CI, 1.76-3.94) and for those who reported a history of injury versus no injury history (HR, 1.76; 95% CI, 1.18-2.64). No differences were observed between BMI categories.

Conclusion:

Female cadets and those reporting previous musculoskeletal injury demonstrated a greater hazard of musculoskeletal injury during cadet basic training. This study did not observe an association between BMI and injury.

Musculoskeletal injuries are commonplace in populations focused on fitness and training. ^{13,17,18,22,43,45} Incident injury is particularly concerning for athletic groups with a greater volume of physical load (such as high exposure to running); it can exceed 79% and varies widely depending on the population. ^22,43,45 The military basic training environment is an example of a population focused on fitness and training. For example, cadet basic training at the United States Military Academy (USMA) represents the first 7 weeks of training for entering cadets. Physically, cadets are required to quickly advance their abilities and perform at the same level as soldiers in regular units across the army, including walking 12 miles (19.2 km) with >35 lb (15.88 kg) of gear; running on multiple days of the week; and passing a physical fitness test comprising pushups, situps, and a 2-mile (3.2-km) run in just 7 weeks. ⁴¹

The rapid increase in cumulative physical load significantly affects the musculoskeletal system, particularly in the lower extremity. Though often perceived as an effective strategy for enhancing physical performance, the disadvantage is that 75% of all musculoskeletal injuries in military training are due to “cumulative microtraumatic injuries caused by repeated low intensity forces.” ¹³ Overuse injuries including muscular strains, tendinitis, medial tibial stress syndrome, and stress fractures represent a significant financial burden, costing the US Army nearly $200 million each year ¹³ and negatively affecting training, combat operations, and military readiness. ²⁷ Given the effect of these injuries, it is important to take continued steps toward mitigation. An epidemiological study to identify the factors and mechanisms associated with injury is a key step toward sports injury mitigation. ⁴⁴

Evidence suggests that body mass index (BMI) is one important risk factor to consider given its correlation with musculoskeletal injury in the athletic population. ^43,46 Both higher and lower BMI have been correlated with injury in the US Army basic training population. ^15,18 Previous injury is also a well-known predictor of future injury in many sports and activities in both civilian and military populations. ^{10,17,20,26,36,39} Finally, sex is a significant correlate to injury in the military population, where women are injured at nearly twice the rate of their male counterparts, ^14,17,31 particularly less fit women. ¹⁹ Alongside these potential risk variables, it is also important to assess load toleration and the schedule of training. Researchers have asserted that it is not just the cumulative load but the time over which that load is experienced that is correlated with musculoskeletal injuries. ^6,7,37 The temporal aspect of the load application offers a valuable option for injury mitigation through better understanding of time varying load application. ^23,30

To best inform future training, load application, and intervention to maximize injury mitigation in military training and sports, we must delineate the timing of injury and how that timing differs based on certain risk factors. Therefore, the purpose of this study was to examine both the incidence and the timing of injuries during cadet basic training. The study examined overall and specific injury types in addition to overall and subgroup injury timing. Subgroups examined included sex, history of injury, and BMI category. Additionally, we compared survivability of injury between groups using time-to-event analyses. We hypothesized that women, those with a history of injury, and those in the underweight and obese BMI categories would be injured earlier in the training period than men, those without injury history, and those in the normal-weight BMI category.

Methods

Participants and Data Collection

Data on injury history, demographics, and injury surveillance were collected at USMA in 2018. The study represented a partnership between military and civilian institutions and was reviewed by the Regional Health Command–Atlantic Institutional Review Board and the University of North Carolina at Chapel Hill Institutional Review Board.

All individuals were recruited from the population of new cadets arriving at USMA to enter cadet basic training as part of the class of 2022. Recruitment occurred on day 2 of training, where the tests and procedures were explained. Information was delivered both orally and in written format. Because of the USMA’s age standards for entry, all participants were emancipated minors or adults between the ages of 17 and 22 years and met height and weight requirements. ⁴⁰ Inclusion criteria included being eligible to begin training, and cadets who consented to the study were excluded only if they stated they felt pain or did not feel as though they could complete the physical tests that were part of normal screening, including a jump landing and Army Physical Fitness Test (see Appendix Table A1). Participants understood that they were not receiving any reimbursement for participation in either of the studies. The injury surveillance period was the first 60 days of cadet basic training.

Injury Surveillance and Outcomes

Injury surveillance data originated from internal electronic medical records at USMA. Specifically, these data were collected from 2 databases: the Cadet Injury and Illness Tracking System (which is specific to USMA) and the Armed Forces Health Longitudinal Technology Application (which is US Department of Defense–wide). Because the USMA uses a closed medical system, meaning that the medical needs of the cadets are met within the military health system, all injury data are entered into 1 of these 2 systems. In the normal course of events, if a cadet feels pain and/or sustains what is perceived to be an injury, he or she presents to sick call, where a health care provider documents the details of the pain/injury, the diagnosis, and plan of care in the electronic medical record. Details of any visit to medical providers, including medical doctors, physician assistants, or physical therapists, are placed in the record.

Using International Classification of Diseases, 10th revision (ICD-10) codes, we conducted an extensive review of injuries that occurred during the first 60 days for cadets entering the USMA in 2018 within both electronic medical record systems. The majority of injury codes used were overuse in nature. Joint and soft tissue pain codes were also included. ^12,13,31 A complete list of the ICD-10 codes used in the search can be found in Appendix Table A2.

For the purpose of this study, we defined an injury as any condition of the musculoskeletal system involving the lower extremities or pelvis for which the individual sought medical care. Cadet basic training is normally 48 days in length, but we included 12 days after return from training in order to capture those injuries that were sustained during but not reported until after completion of training.

Demographic and Historical Injury Data

Data on history of injury came from questions on the baseline questionnaire answered immediately after providing consent. The questionnaire asked separate questions about injuries to lower extremity anatomic locations. If the cadet answered in the affirmative to having a lower extremity injury, he or she was categorized as having a positive injury history; if one answered in the negative to all injury questions, the cadet was considered to have a negative injury history. A missing response was assumed to represent the absence of an injury.

BMI was calculated from the height and weight measured during the day 2 physical fitness test and categorized into 3 groups: underweight (<20); middleweight (20-29.99); and obese (≥30). The American Dietetic Association ³⁵ defines underweight as having a BMI of less than 20. Similarly, 20 has been suggested as a cutoff for underweight for geriatric patients in European countries ²⁴ and Japan. ²⁵  Finally, sex was a variable collected as part of general demographic information. Sex was defined as a dichotomous variable with either male or female as the potential group. This was in accordance with the demographic selection options at USMA.

Statistical Analysis

Baseline descriptive statistics, including days until injury, were calculated for each type of injury as well as for each subgroup (ie, male/female). We created survival curves using the Kaplan-Meier method. The interpretation of the survival curve is that it plots the probability of being event-free on any given day of basic training having survived injury-free up to the day. ⁴⁷ The population was a fixed-size closed cohort, as all cadets start training on the same date and all consented on the same day. No individuals could enter the study at a later date, and administrative right censoring was performed at the completion of the surveillance period (60 days). The log-rank test was used to quantify the difference between the survival curves.

Additionally, the Cox proportional hazards model was used to estimate hazard ratios (HRs). Like the survival function, a hazard can be interpreted as the conditional rate of the injury occurrence on any given day of training, given that the individual has not experienced injury before that point in time. The HR is estimated from the proportional hazards model, which is written as h_x (t) = h ₀(t) × e ^βx , where h ₀ is the baseline hazard over time for a referent subgroup (eg, men), h_x is the hazard in the comparison group (eg, women), x represents women (1) or men (0), and β is the natural log of the HR. We used 95% confidence intervals (CIs) to determine the significance of the variables, and the proportionality of hazards was evaluated by assessing the significance of time interactions in the model (α = .05). Statisitical Analyses were performed using SAS Version 9.3 (SAS Institute).

Results

Central Tendency Measures of Time to Event

A total of 595 cadets consented to and provided data for the study (48.4% of the class). A breakdown of preinjury baseline characteristics is presented in Table 1. Similar to the overall incoming cadet population in 2018, which was 76.1% male, ⁴² the cohort was also largely male (n = 457; 76.81%). Overall, 178 cadets (29.92%) reported a history of injury before starting at USMA. BMI ranged from 18.2 to 40.7, with 19 cadets (3.19%) having a BMI ≥30 and 21 (3.53%) having a BMI of <20. No women had a BMI of ≥30 versus 19 men. Six women had a BMI of <20 versus 15 men.

Table 1.

Baseline Characteristics: Entering Cadets at the United States Military Academy, 2018 ^a

Characteristic	n (%)
Sex
Male	457 (76.81)
Female	138 (23.19)
BMI
<20 (underweight)	21 (3.53)
20-29.99	555 (93.28)
≥30 (obese)	19 (3.19)
History of injury
Yes	178 (29.92)
No	417 (70.08)

^a BMI, body mass index.

During the first 60 days at USMA, 97 of the 595 cadets (16.3%) experienced a training-related musculoskeletal injury. Of these injuries, 9 (9.3%) were stress fractures, which represented a 1.5% cumulative incidence of stress fracture in the cohort during the 60 days of cadet basic training. Among female cadets, 29.7% sustained at least 1 injury compared with 12.3% of male cadets (P < .001). For stress fractures, female cadets had an incidence of injury of 2.9% compared with 1.1% of male cadets (P = .128). Female incidence of soft tissue injury was also greater at 26.8% relative to men at 10.9% (P < .001). Mean and median times to musculoskeletal injury for each subgroup based on sex, history of previous injury, and BMI are shown in Table 2.

Table 2.

Injury Characteristics: Entering Cadets at the United States Military Academy, 2018 ^a

	All Injuries			Stress Fractures			Soft Tissue Injuries
	n	Mean ± SD	Median (IQR)	n	Mean ± SD	Median (IQR)	n	Mean ± SD	Median (IQR)
Overall	97	19.14 ± 14.19	15.00 (5.00-25.00)	9	16.56 ± 12.36	13.00 (9.00-17.00)	87	19.63 ± 14.33	17.00 (7.00-27.00)
Sex
Male	56	18.00 ± 14.56	13.00 (2.75-23.25)	5	19.80 ± 16.27	9.00 (0.00-36.00)	50	18.18 ± 14.47	13.50 (3.50-23.50)
Female	41	20.71 ± 13.68	18.00 (10.75-25.50)	4	12.50 ± 3.87	13.50 (8.50-18.50)	37	21.60 ± 14.09	19.00 (12.00-26.00)
History of injury
Yes	41	23.12 ± 15.60	19.00 (8.50-29.50)	1	7.00 ± N/A	7.00 (N/A b )	40	23.53 ± 15.58	19.00 (9.50-28.50)
No	56	16.23 ± 12.41	13.00 (5.25-20.75)	8	17.75 ± 12.65	13.50 (5.00-22.00)	47	16.32 ± 12.40	13.00 (5.00-21.00)
BMI
<20 (underweight)	5	18.20 ± 7.98	21.00 (11.50-30.50)	0	N/A b	N/A b	5	18.20 ± 7.98	21.00 (20.00-22.00)
20-29.99	90	19.44 ± 14.51	15.00 (5.00-25.00)	9	16.56 ± 12.36	13.00 (9.00-17.00)	80	20.01 ± 14.69	16.00 (5.75-26.25)
≥30 (obese)	2	8.00 ± 8.49	8.00 (2.00-14.00)	0	N/A b	N/A b	2	8.00 ± 8.49	8.00 (2.00-14.00)

^a BMI, body mass index; IQR, interquartile range; N/A, not applicable.

^b N/A denotes categories with 0 or 1 injuries, where calculations could not be completed.

Survival Analysis Comparisons

Injury-free survival time during the follow-up period was compared using Kaplan-Meier curves (Figures 1 –3) that compared subgroup survival and HRs (Table 3). The proportional hazard assumptions were met for all comparisons, as indicated by a nonsignificant time interaction; however, it must be noted that for BMI, the Kaplan-Meier survival curves did cross, indicating the possibility of violation of proportionality of hazard (P _Time×BMI = 0.242).

Figure 1.

Kaplan-Meier curves by sex for incident musculoskeletal injury during basic training for entering cadets at the United States Military Academy, 2018. See Appendix Table A1 for details on events. APFT, Army Physical Fitness Test; CBT, cadet basic training; Comp, competition.

Figure 2.

Kaplan-Meier curves by history of injury for incident musculoskeletal injury during basic training for entering cadets at the United States Military Academy, 2018. See Appendix Table A1 for details on events. APFT, Army Physical Fitness Test; CBT, cadet basic training; Comp, competition.

Figure 3.

Kaplan-Meier curves by body mass index (BMI) for incident musculoskeletal injury during basic training for entering cadets at the United States Military Academy, 2018. See Appendix Table A1 for details on events. APFT, Army Physical Fitness Test; CBT, cadet basic training; Comp, competition.

Table 3.

Hazard Ratios for Musculoskeletal Injury During Cadet Basic Training at the United States Military Academy, 2018 ^a

Potential Risk or Protective Factor	Univariate HR (95% CI)	Multivariate HR (95% CI)
Sex (female vs male)	2.63 (1.76-3.94)	2.52 (1.68-3.78)
History of injury (yes vs no)	1.76 (1.18-2.64)	1.63 (1.09-2.44)
BMI
<20 vs 20-29.99	1.52 (0.62-3.73)	N/A
≥30 vs 20-29.99	0.65 (0.16-2.63)	N/A
20 vs ≥30	2.34 (0.45-12.06)	N/A

^a BMI, body mass index; HR, hazard ratio; N/A, not applicable, not included in the multivariate model because of sparse numbers in 2 of the 3 BMI categories.

There were significant differences in survival time between men and women for lower extremity injury during the follow-up period (log-rank test, P < .001). There was notable separation between the 2 groups that emerged around week 3 of training (Figure 1). Univariate HRs (Table 3) also indicated female cadets face a greater hazard of injury during training than do male cadets (HR, 2.63; 95% CI, 1.76-3.94). Multivariate analysis including injury history as a variable produced similar results (HR, 2.52; 95% CI, 1.68-3.78) (Table 3).

Significant differences in time to injury were also observed for those reporting a history of injury relative to those reporting no history of injury (log-rank test, P < .006). Separation in survival curves between these groups appeared to expand during week 4 (Figure 2). Those with a prior history of injury had a greater hazard of incident injury than did those with no injury history in univariate analysis (HR, 1.76; 95% CI, 1.18-2.64) and in the multivariate analysis adjusting for sex (HR, 1.63; 95% CI, 1.09-2.44) (Table 3).

Comparison across the 3 categories of BMI were problematic because of distinct homogeneity of the sample. Underweight and obese categories were very underrepresented in the cadet population (Table 1). Based on visual inspection, it appeared that underweight individuals experienced a decline in survival (ie, higher rate of injury) after the Warrior Competition, though no statistically significant differences were found (Figure 3).

Discussion

Survival curve and HR comparisons indicated less survival time to musculoskeletal injury and greater hazard of injury for women and those with a history of injury. The differences were specifically noted after the first 2 weeks of training. The disparities offer an opportunity to improve injury mitigation by appropriately focusing both screening and intervention in the military and sports. The results matched our hypotheses for survival time by sex and injury history but not for BMI. However, this likely reflected the very low numbers of underweight and obese cadets in this population. Our observations may indicate a distinct difference in load tolerances among cadets and inform mitigation based on individual characteristics.

Cumulative Incidence for Injury Outcomes of Interest

The overall incidence of injury was equivocal to previous studies on USMA cadets but slightly less than the incidence of injury in army basic training overall. ^13,15,20 Stress fracture incidence, specifically, was slightly lower than in previous cohorts of USMA cadets ²⁰ and moderately lower than that found in other army basic training environments. ^13,15

Differences in Survival by Sex

Our observation of a greater hazard of musculoskeletal injury for women throughout training is consistent with several studies that have highlighted a greater risk of musculoskeletal injury for women during military training. ^20,32,38 There are a number of potential reasons for the noted disparities between the sexes. For example, when compared with their male counterparts, women demonstrate decreased absolute strength and power of the upper and lower extremities. ^2,8 Women are also generally smaller with less muscle mass. Given that training loads are equal for both sexes, female cadets may require comparatively more effort during training. Appropriate physical training is known to build strength and increase tissue capacity. However, the greater proportional effort by female cadets could push them beyond supraphysiologic overloading ⁵ and toward structural failure.

Supraphysiologic overloading also appears to have a temporal component in this population. ^4,6,29 Our data further suggested that the temporal component differs between the sexes and begins to diverge early, at the more exhaustive events (eg, the Warrior Competition, 12-mile ruck). We speculate that the acute effort needed to complete these events (ie, load placed upon the tissues), particularly for female cadets, was far greater than the average (ie, chronic) load placed on tissues over the previous weeks. Spikes in an acute to chronic workload ratio have been shown to increase injury risk. ^4,6,9 Thus, these data support the developing case in the military literature that injury rate may also be a function of physical condition at the start of training. ^1,16

Differences in Survival by History of Injury

Our observations that those with a history of injury demonstrated a greater hazard of musculoskeletal injury is consistent with injury history’s being correlated with greater risk of injury in a variety of populations. ^{10,17,27,36,39} Specific to the cadet population at USMA, Kucera et al ²⁰ demonstrated a strong correlation between injury history and injury incidence in cadet basic training. We propose 2 reasons that this specific relationship could exist, both relating to the concept of tissue overload. First, the risk of injury may lie with lack of proper rehabilitation and less optimal tissue capacity. ²⁸ Second, reduced tissue capacity for both load and recovery could lead to less survival time until injury due to the inability to remodel in sufficient time to tolerate the subsequent load without injury.

There is also evidence to suggest a disruption of sensorimotor abilities after injury, ²⁸ which describes the second reason those with a history of injury may experience less time to injury---that lingering kinematic and/or neuromuscular deficits result in altered movement and loading profiles. Evidence for altered loading profiles is found elsewhere in the literature, particularly in those who have undergone anterior cruciate ligament reconstruction where altered kinematic changes can follow injury. ^11,21 Changes in one’s kinematic or kinetic profile may alter the tissue-specific loads experienced during training. This change appears to decrease the load tolerance of the tissue for some, again leading the person to exceed the zone of supraphysiologic overload and resulting in a decreased time until injury.

Differences in Survival by BMI

Though the survival curves appear to show a drop after the Warrior Competition, our analysis showed no statistical difference between categories of BMI. It is important to note, however, that the obese and underweight categories were underrepresented in the cadet population and our BMI analyses were affected by lack of precision, as evidenced by the wide CIs for the BMI HRs. Previous research is conflicting regarding BMI and injury. Psaila and Ranson ³⁴ reported that BMI was not associated with injury risk, while Jones et al ¹⁵ found that men with greater BMI had greater risk of musculoskeletal injury during training. Knapik et al ¹⁸ described a univariate correlation between injury risk and recruits with both high and low BMI, though only low BMI was observed to be valuable as an independent risk factor in their Cox regression model. The apparent drop in the survival curve after the Warrior Competition for the underweight category also occurs in week 3, which is common in basic training ^3,33 and thus may be a function of the cumulative load at that point and not the Warrior Competition itself.

Limitations

As with any study, there were inherent weaknesses that bear highlighting. First, our sample included 48.4% of the class. Though this was a robust number, certain categories, including the underweight and obese BMI categories, were underrepresented because they are similarly underrepresented in the population because of admissions standards. ⁴⁰ With regard to injury, 29.9% of the sample reported injury before attending USMA, and 16.3% of the sample experienced injury during the follow-up period. Second, the timing of major physical events does not highlight proximity to other training events that may have altered the true or perceived tissue load experienced by the individual cadet. For example, cadets from one company may have gone directly from a range or night training to a major physical event, while cadets from another company may have been more rested. Though cadets all do the same training, limitations on space and equipment require their training to be conducted at different times. Third, the day of injury used is the day the injury was reported to medical personnel, which may or may not be the day the injury was actually sustained. Fourth, we only examined injuries to the lower extremities in this study, potentially limiting our ability to understand the full effect of musculoskeletal injury during this period. Finally, we were not able to control for other potentially important variables, including race and the level of athletics in which the cadets participated (recreational vs intercollegiate).

Strengths

This study was innovative because it used survival methods to analyze time until injury, which provides information to those planning training schedules. The survival curves in Figures 1 to 3 include major training schedule events during cadet basic training, which highlight the significant physical events required of the cadets and those events’ temporal relationship to survival to musculoskeletal injury. This manner of delineating the survival time until injury has the capability of enhancing the current methodology in developing cadet basic training. Using these types of injury analyses is clinically applicable, as they can better inform load application and highlight where overloading may occur, all of which optimize load application and can help mitigate injury risk. ³⁷

Conclusion

Survival analyses demonstrated that being male and having no history of injury were correlated with less hazard of musculoskeletal injury during cadet basic training at the USMA versus being female and having a history of injury. The disparity between these groups appears to be particularly evident after week 2. Research on fitness state before cadet basic training could be beneficial in understanding the acute to chronic workload change during the first segment of training. Finally, the use of more exact load monitoring could more precisely delineate survival until training-related injury by using total load versus days until injury.

APPENDIX

Table A1.

Definitions of Cadet Basic Training Events

• Army Physical Fitness Test: this test consists of 2 min of pushups followed by 2 min of situps followed by a 2-mile run

• Ruck: short for ruck marching, these are events in which a cadet wears a tactical uniform, gear, and a ruck sack, which is much like a large backpack. Normal weight for gear is at least 35 lb (15.88 kg).

• Warrior Competition: a multiple task event that simulates combat-related tasks (ie, carrying another cadet on a stretcher) and requires small group problem solving along with the physical tasks

• Cadet basic training complete: this is the day that cadets are accepted into the larger corps of cadets and begin the transition to their academic studies.

• First long weekend: this is typically Labor Day weekend (weekend of the first Monday in September), in which cadets have no academic requirements Saturday through Monday.

Table A2.

ICD-10 Codes ^a

Injury	ICD-10 Code	Injury	ICD-10 Code
Acute ankle and foot injuries		Acute knee and lower leg injuries
Talar dome fracture	S92.1	Gastrocnemius strain	S86.1
Calcaneal fracture	S99.0	Fibular fracture	S82.4
Cuboid subluxation/dislocation	S93.31	Tibial fracture	S82.2
Toe sprain	S93.51	Lower leg compartment syndrome (traumatic)	T79.A
Great toe fracture	S92.4	MCL sprain	S83.41
Phalangeal fracture (digits 2-5)	S92.5	LCL sprain	S83.42
Phalangeal dislocation	S93.1	ACL sprain	S83.51
Sprain of interphalangeal joint	S93.51	PCL sprain	S83.52
Ankle sprain (medial or lateral)	S93.4	Meniscal tear	S83.2
High ankle sprain (syndesmotic ankle sprain)	S93.43	Patellar fracture	S82.0
Distal fibular fracture	S82.6	Patellar subluxation/dislocation	S83.0
Distal tibial fracture	S82.3	Patellar tendon rupture	M66.85
Achilles tendon rupture	S86.02	Dislocation of knee	S83.1
Peroneal tendon subluxation/dislocation	S86.39	Sprain of other specified sites of knee and leg	S83.8
Ankle dislocation	S93.0	Sprain of unspecified site of knee and leg	S83.9
Tarsal (bone) dislocation, joint unspecified	S93.31	Pain in thigh	M79.65
Midtarsal (joint) dislocation	S93.31	Pain in lower leg	M79.67
Tarsometatarsal (joint) dislocation	S93.32
Metatarsophalangeal (joint) dislocation	S93.12	Chronic knee and lower leg injuries
Interphalangeal (joint) dislocation, foot	S93.11	Medial tibial stress syndrome	M76.89, T79.6
Sprain of foot	S93.5	Chronic compartment syndrome	M79.A
Sprain of tarsometatarsal (joint) (ligament)	S93.62	Tibial stress fracture	M84.361, M84.362
Sprain of metatarsophalangeal (joint)	S93.52	Fibular stress fracture	M84.363, M84.364
Sprain of interphalangeal (joint), toe	S93.51	Bursitis - infrapatellar, suprapatellar	M70.4
Sprain of foot (unspecified) (other)	S93.60	Chondromalacia (patella)	M22.4
Pain in foot and toes	M.79.67	Patellofemoral pain	M22.2
		Iliotibial band friction syndrome	M76.3
Chronic ankle and foot injuries		Pes anserine tendinitis	M76.89
Talar dome stress fracture	S92.19	Patellar tendinitis	M76.5
Tarsal tunnel syndrome	G57.5	Knee osteoarthritis	M17.1
Plantar fasciitis	M72.2	Pain in knee	M25.56
Metatarsal stress fracture	M84.374, M84.375
Sesamoiditis	M25.80	Acute hip, thigh, and pelvic injuries
Metatarsalgia	M77.40	Quadriceps strain	S76.1
Morton’s neuroma	G57.60	Hamstring strain	S76.3
Achilles tendinitis	M76.6, M79.61	Femoral fracture (distal)	S72.4
Anterior tibialis tendinitis	M76.81	Femoral fracture (proximal)	S72.0
Posterior tibialis tendinitis	M76.82	Femoral head dislocation/subluxation	S73.0
Peroneal tendinitis	M76.7	Hip joint sprain	S73.1
		Adductor strain	S76.2
		Chronic hip, thigh, and pelvic injuries
		Femoral stress fracture	M84.35
		Trochanteric bursitis	M70.6
		Osteitis pubis	M85.3

^a ACL, anterior cruciate ligament; ICD, International Classification of Diseases; LCL, lateral collateral ligament; MCL, medial collateral ligament; PCL, posterior cruciate ligament.